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Medications for Pain

About Pain

An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage.

Drugs used to treat Pain

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
tramadol 6.0 646 reviews
Rx C 4 X

Generic name: tramadol systemic

Brand names:  Ultram, ConZip, Qdolo

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

gabapentin Off-label 6.2 350 reviews
Rx C N X

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Norco 6.8 185 reviews
Rx C 2 X

Generic name: acetaminophen / hydrocodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ibuprofen 7.8 46 reviews
Rx/OTC C N X

Generic name: ibuprofen systemic

Brand names:  Advil, Motrin, Advil Liqui-Gels, Motrin IB, A-G Profen, Actiprofen, Addaprin, Advil Children's, Advil Infant's Concentrated Drops, Advil Migraine, Caldolor, Children's Motrin, Genpril, IBU-200, Midol IB, Motrin Childrens, Motrin Junior Strength, Nuprin, Proprinal …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

oxycodone 8.5 447 reviews
Rx N 2 X

Generic name: oxycodone systemic

Brand names:  OxyContin, Roxicodone, Dazidox, ETH-Oxydose, Oxaydo, Oxydose, Oxyfast, Xtampza ER …show all

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

acetaminophen 6.6 46 reviews
Rx/OTC C N X

Generic name: acetaminophen systemic

Brand names:  Tylenol, Paracetamol, Tylenol Arthritis Pain, Arthritis Pain Relief, Mapap, Tylenol 8 Hour, 7T Gummy ES Chewable Tablets, Abenol, Acephen, Actamin, Actimol Children's, Actimol Infant, Altenol, Aminofen, Anacin Aspirin Free, Apra, Atasol, Aurophen, Cetafen, Children's Silapap, Children's Tylenol, Dolono, Equaline Pain Relief, Febrol Solution, Feverall, Genapap, Genebs, Infant's Tylenol, Jr. Tylenol, M-Pap, Mapap Arthritis Pain, Nortemp Children's, Ofirmev, Pharbetol, Silapap Childrens, Tactinal, Tempra Quicklets, Topcare 8 Hour Pain Relief, Topcare Arthritis Pain Relief, Tycolene, Tylophen, Vitapap …show all

Drug class: miscellaneous analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

hydrocodone 5.7 177 reviews
Rx C 2 X

Generic name: hydrocodone systemic

Brand names:  Zohydro ER, Hysingla ER

Drug class: narcotic analgesics, antitussives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Dilaudid 8.2 241 reviews
Rx C 2 X

Generic name: hydromorphone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

acetaminophen / hydrocodone 6.8 650 reviews
Rx C 2 X

Generic name: acetaminophen / hydrocodone systemic

Brand names:  Norco, Lortab, Anexsia, Hycet, Co-Gesic, Lorcet, Lorcet Plus, Theracodophen Low 90, Verdrocet, Xodol, Zyfrel …show all

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

methadone 8.7 162 reviews
Rx C 2 X

Generic name: methadone systemic

Brand names:  Methadone Diskets, Methadose

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Tylenol 6.8 12 reviews
Rx/OTC C N X

Generic name: acetaminophen systemic

Drug class: miscellaneous analgesics

For consumers: dosage, interactions, side effects

OxyContin 8.8 196 reviews
Rx N 2 X

Generic name: oxycodone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

buprenorphine 6.3 133 reviews
Rx C 3 X

Generic name: buprenorphine systemic

Brand names:  Buprenex, Belbuca, Butrans

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Percocet 8.8 184 reviews
Rx C 2 X

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Buprenex 10 4 reviews
Rx C 3 X

Generic name: buprenorphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Lortab 8.2 91 reviews
Rx C 2 X

Generic name: acetaminophen / hydrocodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Celebrex 7.0 90 reviews
Rx C N

Generic name: celecoxib systemic

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Paracetamol 4.0 8 reviews
Rx/OTC C N X

Generic name: acetaminophen systemic

Drug class: miscellaneous analgesics

For consumers: dosage, interactions, side effects

naproxen 6.2 95 reviews
Rx/OTC C N X

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Aflaxen, All Day Pain Relief, All Day Relief, Anaprox, Anaprox-DS, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Ultram 6.1 122 reviews
Rx C 4 X

Generic name: tramadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ketorolac 6.7 346 reviews
Rx C N X

Generic name: ketorolac systemic

Brand name:  Sprix

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

amitriptyline 7.7 228 reviews
Rx C N X

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

acetaminophen / oxycodone 8.3 428 reviews
Rx C 2 X

Generic name: acetaminophen / oxycodone systemic

Brand names:  Percocet, Endocet, Nalocet, Primlev, Prolate, Xolox …show all

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

diclofenac 7.2 176 reviews
Rx D N X

Generic name: diclofenac systemic

Brand names:  Voltaren, Cataflam, Zipsor, Zorvolex …show all

Drug class: Nonsteroidal anti-inflammatory drugs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Nucynta 6.2 262 reviews
Rx C 2 X

Generic name: tapentadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Topics under Pain

Alternative treatments for Pain

The following products are considered to be alternative treatments or natural remedies for Pain. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Pain.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.