Acetaminophen/hydrocodone Interactions
There are 683 drugs known to interact with acetaminophen/hydrocodone, along with 19 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 216 are major, 456 are moderate, and 11 are minor.
- View all 683 medications that may interact with acetaminophen/hydrocodone
- View acetaminophen/hydrocodone alcohol/food interactions (1)
- View acetaminophen/hydrocodone disease interactions (19)
Most frequently checked interactions
View interaction reports for acetaminophen / hydrocodone and the medicines listed below.
- Aspirin Low Strength (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Nexium (esomeprazole)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Acetaminophen/hydrocodone alcohol/food interactions
There is 1 alcohol/food interaction with acetaminophen / hydrocodone.
Acetaminophen/hydrocodone disease interactions
There are 19 disease interactions with acetaminophen / hydrocodone which include:
- alcoholism
- liver disease
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
More about acetaminophen / hydrocodone
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- Reviews (1,316)
- Drug images
- Latest FDA alerts (11)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: narcotic analgesic combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Tramadol
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Cyclobenzaprine
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Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Aspirin
Aspirin is used to treat mild to moderate pain and to reduce fever or inflammation. Learn about ...
Ibuprofen
Ibuprofen (Advil, Motrin) treats minor aches and pains caused by the common cold, headaches ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
