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Medications for Cough

Other names: Chronic Cough; Cough, chronic

About Cough

A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material.

Drugs used to treat Cough

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
benzonatate 4.0 607 reviews
Rx C N

Generic name: benzonatate systemic

Brand names:  Tessalon Perles, Tessalon

Drug class: antitussives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Mucinex 5.7 43 reviews
Rx/OTC C N

Generic name: guaifenesin systemic

Drug class: expectorants

For consumers: dosage, side effects

For professionals: Prescribing Information

Cheratussin AC 4.8 33 reviews
Rx/OTC C M X

Generic name: codeine / guaifenesin systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Benadryl 9.7 4 reviews
Rx/OTC B N X

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Promethazine DM 5.1 14 reviews
Rx C N X

Generic name: dextromethorphan / promethazine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

guaifenesin 5.8 83 reviews
Rx/OTC C N

Generic name: guaifenesin systemic

Brand names:  Mucinex, Altarussin, Amibid LA, Balminil Expectorant, Benylin E, Bidex-400, Drituss G, Fenesin IR, Guaifenex G, Guaifenex LA, Guiatuss, Hytuss, Mucinex for Kids, Mucinex Maximum Strength, Robafen, Scot-Tussin Expectorant, Tussin Expectorant, Xpect …show all

Drug class: expectorants

For consumers: dosage, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Tessalon Perles 5.5 130 reviews
Rx C N

Generic name: benzonatate systemic

Drug class: antitussives

For consumers: dosage, interactions, side effects

Tussionex Pennkinetic 9.4 84 reviews
Rx C 2 X

Generic name: chlorpheniramine / hydrocodone systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Robitussin Cough + Chest Congestion DM 9.0 4 reviews
Rx/OTC C N X

Generic name: dextromethorphan / guaifenesin systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

dextromethorphan 3.7 324 reviews
Rx/OTC C N X

Generic name: dextromethorphan systemic

Brand names:  Delsym, Delsym 12 Hour Cough Relief, Robitussin CoughGels Long-Acting, Babee Cof, Buckleys Mixture, Creomulsion, DexAlone, ElixSure Cough, Hold, Robafen Cough Liquidgels, Scot-Tussin Diabetes, Silphen DM, Triaminic Long Acting Cough, Vicks Dayquil Cough, Vicks Formula 44 …show all

Drug class: antitussives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Mucinex DM 5.1 8 reviews
Rx/OTC C N X

Generic name: dextromethorphan / guaifenesin systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Hycodan 8.7 34 reviews
Rx C 2 X

Generic name: homatropine / hydrocodone systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

codeine / promethazine 7.0 58 reviews
Rx C 5 X

Generic name: codeine / promethazine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

codeine / guaifenesin 5.5 86 reviews
Rx/OTC C M X

Generic name: codeine / guaifenesin systemic

Brand names:  Cheratussin AC, Guaiatussin AC, Virtussin A / C, Guaifenesin AC, Allfen CD, Cheracol with Codeine, Codar GF, Duraganidin NR, ExeClear-C, M-Clear WC, Mar-cof CG, Mytussin AC, Robafen AC …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Delsym 3.3 207 reviews
Rx/OTC C N X

Generic name: dextromethorphan systemic

Drug class: antitussives

For consumers: dosage, interactions, side effects

Tessalon 5.7 29 reviews
Rx C N

Generic name: benzonatate systemic

Drug class: antitussives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Hydromet 8.2 31 reviews
Rx C 2 X

Generic name: homatropine / hydrocodone systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Dilaudid 9.0 2 reviews
Rx C 2 X

Generic name: hydromorphone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

diphenhydramine 9.0 5 reviews
Rx/OTC B N X

Generic name: diphenhydramine systemic

Brand names:  Benadryl, Benadryl Allergy, Allermax, Banophen, Benadryl Children's Allergy, Complete Allergy Relief, Dicopanol, Diphedryl, Diphen, Dytuss, Scot-Tussin Allergy, Siladryl Allergy, Twilite, Valu-Dryl …show all

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

dextromethorphan / guaifenesin 6.4 16 reviews
Rx/OTC C N X

Generic name: dextromethorphan / guaifenesin systemic

Brand names:  Robitussin Cough + Chest Congestion DM, Mucinex DM, Tussin DM, Coricidin HBP Chest Congestion & Cough, Mucinex DM Maximum Strength, Aquatab DM, Bidex-A, Biocotron, Biospec DMX, Broncotron, Delsym Cough+ Chest Congestion DM, Fenesin DM IR, G-Zyncof, Guaifenex DM, Guiadrine DX, HT Tuss DM, Humibid CS, Mucinex Children's Cough, Phlemex, Safetussin DM, Siltussin DM, Vicks DayQuil Mucus Control DM, Zyncof …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

gabapentin Off-label 6.6 5 reviews
Rx C N X

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

homatropine / hydrocodone 8.0 92 reviews
Rx C 2 X

Generic name: homatropine / hydrocodone systemic

Brand names:  Hycodan, Hydromet, Tussigon

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

chlorpheniramine / hydrocodone 9.4 108 reviews
Rx C 2 X

Generic name: chlorpheniramine / hydrocodone systemic

Brand names:  Tussionex Pennkinetic, TussiCaps

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Guaiatussin AC 0.0 1 review
Rx/OTC C M X

Generic name: codeine / guaifenesin systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Lortab 10 3 reviews
Rx C 2 X

Generic name: acetaminophen / hydrocodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Topics under Cough

Alternative treatments for Cough

The following products are considered to be alternative treatments or natural remedies for Cough. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Cough.

Learn more about Cough

Drugs.com Health Center

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.