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Dextromethorphan / Guaifenesin Dosage

Medically reviewed on June 18, 2018.

Applies to the following strengths: 10 mg-200 mg/5 mL; 10 mg-200 mg; 5 mg-100 mg/2.5 mL; 10 mg-100 mg/5 mL; 20 mg-200 mg/10 mL; 5 mg-100 mg/5 mL; 20 mg-400 mg/20 mL; 15 mg-100 mg/5 mL; 30 mg-600 mg; 6.67 mg-66.7 mg/5 mL; 10 mg-300 mg/5 mL; 20 mg-200 mg/5 mL; 25 mg-225 mg/5 mL; 15 mg-200 mg/5 mL; 10 mg-100 mg; 60 mg-1000 mg; 30 mg-500 mg; 20 mg-400 mg; 10 mg-150 mg/5 mL; 30 mg-800 mg; 20 mg-1200 mg; 60 mg-800 mg; 28 mg-835 mg; 25 mg-600 mg; 20 mg-200 mg/30 mL; 10 mg-200 mg/15 mL; 60 mg-1200 mg; 20 mg-400 mg/5 mL; 15 mg-125 mg/5 mL; 10 mg-187 mg/5 mL; 15 mg-300 mg; 50 mg-1000 mg; 55 mg-1000 mg; 30 mg-575 mg; 30 mg-200 mg/5 mL; 30 mg-650 mg; 30 mg-835 mg; 28 mg-600 mg; 15 mg-400 mg; 5 mg-100 mg; 45 mg-1200 mg; 57.5 mg-775 mg; 15 mg-225 mg/5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough

Immediate release: Dextromethorphan-guaifenesin 10 mg-200 mg oral capsule: 2 capsules every 4 hours/ not to exceed 12 capsules/day

Dextromethorphan-guaifenesin 5 mg-100 mg oral granule: 2 to 4 packets every 4 hours, not to exceed 6 doses/day
Dextromethorphan-guaifenesin 5 mg-100 mg/5 mL oral liquid: 10 mL to 20 mL every 4 hours, not to exceed 120 mL/day
Dextromethorphan-guaifenesin 10 mg-100 mg/5 mL oral liquid: 10 mL every 4 hours, not to exceed 60 mL/day
Dextromethorphan-guaifenesin 10 mg-200 mg/5 mL oral liquid: 10 mL every 4 hours, not to exceed 60 mL/day
Dextromethorphan-guaifenesin 10 mg-200 mg/15 mL oral liquid: 30 mL orally every 4 hours, not to exceed 6 doses in 24 hours
Dextromethorphan-guaifenesin 15 mg-200 mg/5 mL oral liquid: 10 mL every 6 hours, not to exceed 40 mL/day
Dextromethorphan-guaifenesin 20 mg-200 mg/10 mL oral liquid: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours
Dextromethorphan-guaifenesin 20 mg-200 mg/30 mL oral liquid: 30 mL orally every 4 hours, not to exceed 6 doses in 24 hours
Dextromethorphan-guaifenesin 20 mg-400 mg/5 mL oral liquid: 5 mL every 4 hours, not to exceed 6 doses in 24 hours
Dextromethorphan-guaifenesin 20 mg-400 mg/20 mL oral liquid: 20 mL orally every 4 hours, not to exceed 6 doses in 24 hours

Extended release:
Dextromethorphan-guaifenesin 30 mg-600 mg oral tablet, extended release: 1 or 2 tablets every 12 hours, not to exceed 4 tablets/day
Dextromethorphan-guaifenesin 60 mg-1200 mg oral tablet, extended release: 1 tablet every 12 hours. Not to exceed 2 tablets/day

Usual Pediatric Dose for Cough

12 years and older: Follow adult dosing

Dosing varies by product, please refer to specific labeling:

Dextromethorphan-guaifenesin 5 mg-100 mg oral granule:
6 to 12 years: 1 to 2 packets every 4 hours, not to exceed 6 doses/day
Under 6 years: Do not use

Dextromethorphan-guaifenesin 5 mg-100 mg/5 mL oral liquid:
6 to 12 years: 5 mL to 10 mL every 4 hours, not to exceed 60 mL/day
4 to 6 years: 2.5 mL to 5 mL every 4 hours, not to exceed 30 mL/day
Under 4 years: Do not use

Dextromethorphan-guaifenesin 10 mg-100 mg/5 mL oral liquid:
6 to 12 years: 5 mL every 4 hours, not to exceed 30 mL/day
2 to 6 years: 2.5 mL every 4 hours, not to exceed 15 mL/day
Under 2 years: Do not use

Dextromethorphan-guaifenesin 10 mg-200 mg/15 mL oral liquid:
6 to 12 years: 15 mL every 4 hours, not to exceed 30 mL/day
4 to 6 years: Ask a doctor
Under 4 years: Do not use

Dextromethorphan-guaifenesin 20 mg-200 mg/10 mL oral liquid
6 to 12 years: 5 mL every 4 hours, not to exceed 30 mL/day
2 to 6 years: 2.5 mL every 4 hours, not to exceed 15 mL/day
Under 2 years: Do not use

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Dextromethorphan-guaifenesin should be administered with plenty of fluids.

Store oral liquid at room temperature (20C to 25C or 68F to 77F)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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