Dextromethorphan / Guaifenesin Dosage
Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.
Applies to the following strengths: 10 mg-200 mg/5 mL; 10 mg-200 mg; 5 mg-100 mg/2.5 mL; 10 mg-100 mg/5 mL; 20 mg-200 mg/10 mL; 5 mg-100 mg/5 mL; 20 mg-200 mg/20 mL; 20 mg-400 mg/20 mL; 10 mg-100 mg/10 mL; 60 mg-1200 mg; 30 mg-600 mg; 15 mg-100 mg/5 mL; 6.67 mg-66.7 mg/5 mL; 10 mg-300 mg/5 mL; 20 mg-200 mg/5 mL; 25 mg-225 mg/5 mL; 15 mg-200 mg/5 mL; 10 mg-100 mg; 20 mg-400 mg; 60 mg-1000 mg; 30 mg-500 mg; 10 mg-150 mg/5 mL; 30 mg-800 mg; 20 mg-1200 mg; 60 mg-800 mg; 28 mg-835 mg; 25 mg-600 mg; 20 mg-200 mg/30 mL; 10 mg-200 mg/15 mL; 20 mg-400 mg/5 mL; 15 mg-125 mg/5 mL; 10 mg-187 mg/5 mL; 15 mg-300 mg; 50 mg-1000 mg; 55 mg-1000 mg; 30 mg-575 mg; 30 mg-200 mg/5 mL; 30 mg-650 mg; 30 mg-835 mg; 28 mg-600 mg; 15 mg-400 mg; 5 mg-100 mg; 45 mg-1200 mg; 57.5 mg-775 mg; 15 mg-225 mg/5 mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cough
Dose referred to by strength of dextromethorphan/guaifenesin (in mg) per unit of measurement:
10/100 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day
10/187 per 5 mL: 10 mL every 4 hours, maximum 4 doses per day
10/200 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day
20/400 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day
20/200 per 10 mL: 10 mL every 4 hours, maximum 6 doses per day
20/200 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day
20/400 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day
Oral solids (tablets/caplets/capsule/gel caps):
10/200 per caplet: 1 or 2 every 4 hours, maximum 12 caplets per day
20/400 per tablet: 1 tablet every 4 hours, maximum 6 doses per day
30/600 per tablet: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
60/1200 per tablet: 1 tablet every 12 hours, maximum 2 tablets per day
Usual Pediatric Dose for Cough
Dose referred to by strength of dextromethorphan/guaifenesin (in mg) per unit of measurement:
10/100 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
10/187 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 4 doses per day
6 to under 12 years: 5 mL every 4 hours, maximum 4 doses per day
2 to under 6 years: 2.5 mL every 4 hours, maximum 4 doses per day
10/200 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
20/400 per 5 mL 12 years and older: 5 mL every 4 hours, maximum 6 doses per day
20/200 per 10 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
20/200 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day
20/400 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day
Oral solids (tablets/caplets/capsule/gel caps):
10/200 per caplet:
12 years and older: 1 or 2 every 4 hours, maximum 12 caplets per day
20/400 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day
30/600 per tablet:
12 years and older: 1 to 2 tablets every 12 hours, maximum 4 tablets per day
60/1200 per tablet:
12 years and older: 1 tablet every 12 hours, maximum 2 tablets per day
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
