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Dextromethorphan / Guaifenesin Dosage

Medically reviewed by Drugs.com. Last updated on Jul 27, 2023.

Applies to the following strengths: 10 mg-200 mg/5 mL; 10 mg-200 mg; 5 mg-100 mg/2.5 mL; 10 mg-100 mg/5 mL; 20 mg-200 mg/10 mL; 5 mg-100 mg/5 mL; 20 mg-200 mg/20 mL; 20 mg-400 mg/20 mL; 10 mg-100 mg/10 mL; 60 mg-1200 mg; 30 mg-600 mg; 15 mg-100 mg/5 mL; 6.67 mg-66.7 mg/5 mL; 10 mg-300 mg/5 mL; 20 mg-200 mg/5 mL; 25 mg-225 mg/5 mL; 15 mg-200 mg/5 mL; 10 mg-100 mg; 20 mg-400 mg; 60 mg-1000 mg; 30 mg-500 mg; 10 mg-150 mg/5 mL; 30 mg-800 mg; 20 mg-1200 mg; 60 mg-800 mg; 28 mg-835 mg; 25 mg-600 mg; 20 mg-200 mg/30 mL; 10 mg-200 mg/15 mL; 20 mg-400 mg/5 mL; 15 mg-125 mg/5 mL; 10 mg-187 mg/5 mL; 15 mg-300 mg; 50 mg-1000 mg; 55 mg-1000 mg; 30 mg-575 mg; 30 mg-200 mg/5 mL; 30 mg-650 mg; 30 mg-835 mg; 28 mg-600 mg; 15 mg-400 mg; 5 mg-100 mg; 45 mg-1200 mg; 57.5 mg-775 mg; 15 mg-225 mg/5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough

Dose referred to by strength of dextromethorphan/guaiFENesin (in mg) per unit of measurement:

10/100 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day

10/187 per 5 mL: 10 mL every 4 hours, maximum 4 doses per day

10/200 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day

20/400 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day

20/200 per 10 mL: 10 mL every 4 hours, maximum 6 doses per day

20/200 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day

20/400 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day

Oral solids (tablets/caplets/capsule/gel caps):

10/200 per caplet: 1 or 2 every 4 hours, maximum 12 caplets per day

20/400 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

30/600 per tablet: 1 to 2 tablets every 12 hours, maximum 4 tablets per day

60/1200 per tablet: 1 to 2 tablets every 12 hours, maximum 4 tablets per day

Usual Pediatric Dose for Cough

Dose referred to by strength of dextromethorphan/guaiFENesin (in mg) per unit of measurement:

10/100 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day

10/187 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 4 doses per day
6 to under 12 years: 5 mL every 4 hours, maximum 4 doses per day
2 to under 6 years: 2.5 mL every 4 hours, maximum 4 doses per day

10/200 per 5 mL:
12 years and older: 10 mL every 4 hours, maximum 6 doses per day

20/400 per 5 mL 12 years and older: 5 mL every 4 hours, maximum 6 doses per day

20/200 per 10 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day

20/200 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day

20/400 per 20 mL:
12 years and older: 20 mL every 4 hours, maximum 6 doses per day

Oral solids (tablets/caplets/capsule/gel caps):

10/200 per caplet:
12 years and older: 1 or 2 every 4 hours, maximum 12 caplets per day

20/400 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day

30/600 per tablet:
12 years and older: 1 to 2 tablets every 12 hours, maximum 4 tablets per day

60/1200 per tablet:
12 years and older: 1 to 2 tablets every 12 hours, maximum 4 tablets per day

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

  • Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer