Dextromethorphan/guaifenesin Interactions
There are 368 drugs known to interact with dextromethorphan/guaifenesin, along with 1 alcohol/food interaction. Of the total drug interactions, 78 are major, 288 are moderate, and 2 are minor.
- View all 368 medications that may interact with dextromethorphan/guaifenesin
- View dextromethorphan/guaifenesin alcohol/food interactions (1)
Most frequently checked interactions
View interaction reports for dextromethorphan / guaifenesin and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Advil (ibuprofen)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Colace (docusate)
- CoQ10 (ubiquinone)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Gas-X (simethicone)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Paxlovid (nirmatrelvir / ritonavir)
- Pepto-Bismol (bismuth subsalicylate)
- ProAir HFA (albuterol)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Dextromethorphan/guaifenesin alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / guaifenesin.
Report options
More about dextromethorphan / guaifenesin
- dextromethorphan/guaifenesin consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (42)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Mucinex
Mucinex (guaifenesin) is used to relieve the symptoms of cough and loosen mucus in the chest ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Norco
Norco (acetaminophen and hydrocodone) is used to relieve moderate to severe pain. Includes Norco ...
Acetylcysteine
Acetylcysteine systemic is used for acetaminophen overdose, diagnostic bronchograms, dietary ...
Dextromethorphan
Dextromethorphan is a cough suppressant used to treat coughing. Learn about side effects ...
Guaifenesin
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat. Includes ...
Hydromorphone
Hydromorphone systemic is used for anesthetic adjunct, chronic pain, cough, pain
Codeine
Codeine is a opioid pain medicine used to treat mild to moderate pain. Includes codeine side ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
