Dextromethorphan/guaifenesin Interactions
There are 367 drugs known to interact with dextromethorphan/guaifenesin, along with 1 alcohol/food interaction. Of the total drug interactions, 78 are major, 287 are moderate, and 2 are minor.
- View all 367 medications that may interact with dextromethorphan/guaifenesin
- View dextromethorphan/guaifenesin alcohol/food interactions (1)
Most frequently checked interactions
View interaction reports for dextromethorphan / guaifenesin and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Advil (ibuprofen)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Colace (docusate)
- CoQ10 (ubiquinone)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Gas-X (simethicone)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Paxlovid (nirmatrelvir / ritonavir)
- ProAir HFA (albuterol)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Tylenol (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
Dextromethorphan/guaifenesin alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / guaifenesin.
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More about dextromethorphan / guaifenesin
- dextromethorphan/guaifenesin consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (42)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
