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Dilaudid (hydromorphone) Drug Interactions

A total of 829 drugs are known to interact with Dilaudid (hydromorphone).

  • 245 major drug interactions
  • 582 moderate drug interactions
  • 2 minor drug interactions

Show all medications in the database that may interact with Dilaudid (hydromorphone).

Check for interactions

Type in a drug name to check for interactions with Dilaudid (hydromorphone).

Most frequently checked interactions

View interaction reports for Dilaudid (hydromorphone) and the medicines listed below.

  • Advil (ibuprofen)
  • Aleve (naproxen)
  • Ambien (zolpidem)
  • Ativan (lorazepam)
  • Benadryl (diphenhydramine)
  • Cymbalta (duloxetine)
  • fentanyl (Duragesic, Fentanyl Transdermal System, Sublimaze, Fentora, Actiq, Abstral, Lazanda, Subsys, Onsolis, Ionsys)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Motrin IB, Advil Liqui-Gels, Motrin Childrens, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Ibuprofen PMR, Nuprin, NeoProfen, Proprinal, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Advil Infant's Concentrated Drops, Motrin Pediatric, Ibu-Tab, Rufen, Genpril, Haltran, IBU-200, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Motrin Migraine Pain, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Ibu-8, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Advil Film-Coated)
  • Lyrica (pregabalin)
  • methadone (Dolophine, Methadose, Methadone Diskets, Methadose Sugar-Free)
  • morphine (MS Contin, Morphine Sulfate ER, Roxanol, Kadian, Morphine Sulfate IR, MorphaBond ER, MSIR, Duramorph, Statex, Avinza, Oramorph SR, Arymo ER, M-Eslon, Morphine Sulfate SR, Morphine LP Epidural, Astramorph PF, Morphine Rapi-Ject, RMS, Infumorph, Mitigo, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Roxanol-T, Doloral, Doloral Sirop, Morphitec, M O S)
  • naproxen (Aleve, Naprosyn, Anaprox, Naproxen Sodium DS, Naprelan, Anaprox-DS, Flanax Pain Reliever, EC-Naprosyn, Midol Extended Relief, Aflaxen, Comfort Pac with Naproxen, Leader Naproxen Sodium, Pamprin All Day Relief, All Day Pain Relief, All Day Relief)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Dazidox, Oxyfast, Oxecta, RoxyBond, Oxydose, Percolone, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • Percocet (acetaminophen / oxycodone)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Liquid Pred, Meticorten, Orasone, Prednicen-M)
  • Suboxone (buprenorphine / naloxone)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Tramahexal, ConZip, Larapam SR, Ryzolt, Tramal SR, GenRx Tramadol, Tramahexal SR, Tramedo, Zydol, Zamadol, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zofran (ondansetron)

Dilaudid (hydromorphone) alcohol/food interactions

There is 1 alcohol/food interaction with Dilaudid (hydromorphone)

Dilaudid (hydromorphone) disease interactions

There are 16 disease interactions with Dilaudid (hydromorphone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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