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Medications for Chronic Pain

What is Chronic Pain:  Chronic pain is pain that persists or grows worse over a long period of time.

Medications to treat Chronic Pain

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
oxycodone Rx N 2 X 222 reviews
8.0

Generic name: oxycodone systemic

Brand names:  OxyContin, Roxicodone, Oxyfast, OxyIR, Roxicodone Intensol, Dazidox, ETH-Oxydose, Oxaydo, Oxydose, Xtampza ER …

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
tramadol Rx C 4 X 117 reviews
5.0

Generic name: tramadol systemic

Brand names:  Ultram, Ultram ODT, Rybix ODT, Ultram ER, ConZip, Ryzolt …

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
OxyContin Rx N 2 X 65 reviews
8.0

Generic name: oxycodone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Dilaudid Rx C 2 X 49 reviews
8.0

Generic name: hydromorphone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Cymbalta Rx C N X 86 reviews
6.0

Generic name: duloxetine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Roxicodone Rx N 2 X 26 reviews
9.0

Generic name: oxycodone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Percocet 10 / 325 Rx C 2 X 34 reviews
8.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

 
acetaminophen / oxycodone Rx C 2 X 133 reviews
8.0

Generic name: acetaminophen / oxycodone systemic

Brand names:  Percocet 10 / 325, Percocet, Endocet, Percocet 5 / 325, Roxicet, Tylox, Percocet 7.5 / 325, Magnacet, Narvox, Xartemis XR, Xolox, Percocet 2.5 / 325, Perloxx, Primlev, Roxilox …

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Ultram Rx C 4 X 25 reviews
4.0

Generic name: tramadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
MS Contin Rx C 2 X 40 reviews
7.0

Generic name: morphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Percocet Rx C 2 X 23 reviews
8.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Butrans Rx C 3 X 83 reviews
6.0

Generic name: buprenorphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
methadone Rx C 2 X 100 reviews
8.0

Generic name: methadone systemic

Brand names:  Methadose, Methadone Diskets, Dolophine

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
hydromorphone Rx C 2 X 88 reviews
8.0

Generic name: hydromorphone systemic

Brand names:  Dilaudid, Exalgo, Dilaudid-HP, Palladone …

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
morphine Rx C 2 X 113 reviews
7.0

Generic name: morphine systemic

Brand names:  MS Contin, Roxanol, Kadian, Oramorph SR, MSIR, Arymo ER, Astramorph PF, Duramorph, Infumorph, MorphaBond, RMS, Roxanol-T …

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Duragesic Rx C 2 X 12 reviews
8.0

Generic name: fentanyl systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
buprenorphine Rx C 3 X 161 reviews
6.0

Generic name: buprenorphine systemic

Brand names:  Butrans, Buprenex, Belbuca

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
fentanyl Rx C 2 X 122 reviews
8.0

Generic name: fentanyl systemic

Brand names:  Duragesic, Fentora, Abstral, Actiq, Duragesic-50, Duragesic-75, Duragesic-100, Ionsys, Lazanda, Sublimaze, Subsys, Duragesic-12, Duragesic-25 …

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Endocet Rx C 2 X 9 reviews
8.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Percocet 5 / 325 Rx C 2 X 12 reviews
7.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

 
Roxanol Rx C 2 X Add review
10

Generic name: morphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

 
duloxetine Rx C N X 94 reviews
6.0

Generic name: duloxetine systemic

Brand names:  Cymbalta, Irenka

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Exalgo Rx C 2 X 24 reviews
8.0

Generic name: hydromorphone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Kadian Rx C 2 X 13 reviews
8.0

Generic name: morphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Roxicet Rx C 2 X 5 reviews
5.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Learn more about Chronic Pain

Micromedex® Care Notes

Drugs.com Health Center

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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