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Medications for Chronic Pain

About Chronic Pain:  Chronic pain is pain that persists or grows worse over a long period of time.

Drugs Used to Treat Chronic Pain

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
oxycodone N 2 X 495 reviews
6.4

Generic name: oxycodone systemic

Brand names:  OxyContin, Roxicodone, Oxyfast, Dazidox, Xtampza ER, ETH-Oxydose, Oxaydo, Oxydose …show all

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

tramadol C 4 X 218 reviews
5.7

Generic name: tramadol systemic

Brand names:  Ultram, ConZip

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Dilaudid C 2 X 58 reviews
8.7

Generic name: hydromorphone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

OxyContin N 2 X 84 reviews
8.0

Generic name: oxycodone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cymbalta C N X 135 reviews
6.1

Generic name: duloxetine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Fentanyl Transdermal System C 2 X 62 reviews
7.9

Generic name: fentanyl systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

acetaminophen / oxycodone C 2 X 319 reviews
6.0

Generic name: acetaminophen / oxycodone systemic

Brand names:  Percocet, Endocet, Roxicet, Nalocet, Primlev, Xolox, Prolate …show all

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Roxicodone N 2 X 36 reviews
8.8

Generic name: oxycodone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

hydromorphone C 2 X 112 reviews
8.2

Generic name: hydromorphone systemic

Brand name:  Dilaudid

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Ultram C 4 X 35 reviews
5.0

Generic name: tramadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Percocet C 2 X 33 reviews
8.8

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

MS Contin C 2 X 48 reviews
8.0

Generic name: morphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

morphine C 2 X 161 reviews
7.3

Generic name: morphine systemic

Brand names:  MS Contin, Kadian, Astramorph PF, Duramorph, Infumorph, Duramorph PF, MorphaBond ER …show all

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Butrans C 3 X 120 reviews
6.4

Generic name: buprenorphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

methadone C 2 X 146 reviews
8.6

Generic name: methadone systemic

Brand names:  Methadone Diskets, Methadose, Dolophine

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

buprenorphine C 3 X 350 reviews
5.6

Generic name: buprenorphine systemic

Brand names:  Butrans, Belbuca, Buprenex

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

duloxetine C N X 156 reviews
5.9

Generic name: duloxetine systemic

Brand names:  Cymbalta, Irenka

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

fentanyl C 2 X 161 reviews
7.9

Generic name: fentanyl systemic

Brand names:  Fentanyl Transdermal System, Duragesic, Fentora, Actiq, Lazanda, Subsys …show all

Drug class: narcotic analgesics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Duragesic C 2 X 28 reviews
8.5

Generic name: fentanyl systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Endocet C 2 X 12 reviews
8.8

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Kadian C 2 X 15 reviews
8.1

Generic name: morphine systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Roxicet C 2 X 7 reviews
4.0

Generic name: acetaminophen / oxycodone systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ConZip C 4 X Add review
0.0

Generic name: tramadol systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Methadone Diskets C 2 X 9 reviews
9.6

Generic name: methadone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

Methadose C 2 X 5 reviews
8.4

Generic name: methadone systemic

Drug class: narcotic analgesics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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