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User Reviews for Cymbalta to treat Chronic Pain

Cymbalta has an average rating of 6.0 out of 10 from a total of 138 ratings for the treatment of Chronic Pain. 53% of those users who reviewed Cymbalta reported a positive effect, while 32% reported a negative effect.

Cymbalta Rating Summary

6.0/10 Average Rating

138 ratings from 144 user reviews

Compare all 50 medications used in the treatment of Chronic Pain.

16% 22
14% 19
23% 32
7% 9
2% 3
3% 4
4% 5
2% 3
5% 7
25% 34

Reviews for Cymbalta

Lucy · Taken for 1 to 6 months February 26, 2021

“Cymbalta helped a LOT with chronic pain as well as anxiety. I feel so much better with this medication! I feel mental clarity and the constant irritability from chronic pain was completely relieved. I wish I had tried this years ago! I realize not everyone has the same experience with medications but my quality of life has increased significantly! I have nerve pain that has almost totally gone away!”

10 / 10
Felicia · Taken for 1 to 6 months February 24, 2021

“Medical Issues: chronic, back, muscle, joint, anxiety, PTSD and mild depression. I was on tramadol for 12 years. I was assaulted and strangled May 2020, which left me with the feeling of losing myself. Doc put me on klonopin which semi worked, I went back and told him I didn't feel "complete" He put me on Cymbalta. Getting off of it sucked. The first week I had problems sleeping. Also felt a sense of euphoria at first, relaxed like nothing in the world would bother me. I still have loss of appetite since starting Cymbalta, and weight loss. I don't get nearly as much deep sleep as I used to. I wake up randomly at 3 or 4 in the morning. 4 weeks in, this has helped my mood so much, I'm on a level playing field now as far as anxiety goes. So far, it's been a God send for my mental health and physically I wish for less pain, but it's better. I've noticed a difference with standing longer and less tossing and turning.”

8 / 10
Spiro123 · Taken for 1 to 6 months February 12, 2021

“This drug had some side effects the first two weeks I could not get more than one hour of sleep. It takes away some of the chronic pain in my hands and I can get a full night sleep. Give it time to work if you're using it for chronic pain don't quit after one month because it takes a good 6 to 7 weeks to really enjoy the benefits of cymbalta”

9 / 10

Frequently asked questions

Zola · Taken for less than 1 month February 2, 2021

“I tried Cymbalta after suffering TMJ and increased anxiety and depression. I just thought I was tired from the pain but I was depressed. I was put on 30mg to 60mg and it made my TMJ numb and I felt no anxiety but my mood went totally downhill and I stopped. I was previously on prozac for over 10 years and it worked but then pooped out. I think SNRIs are not for me as the side effects were really bad. Fingers crossed I get lucky with the right med.”

2 / 10
Crps warrior · Taken for 1 to 6 months January 15, 2021

“Only on it for six weeks, I was a depressed zombie for three of them, lost all ability to function and could barely get out of bed. Talk about a numbing drug. All these meds are toxic, get back to nature and heal properly.”

1 / 10
John January 13, 2021

“I have Primary Progressive Multiple Sclerosis. I was prescribed Cymbalta for nerve pain. I was told it could cause diarrhea! I started on 30 mg per day, then after 2 weeks increased to 60mg per day. I have never experienced side effects from a medication as dangerous and scary then the ones I had while on Cymbalta. After a week of taking 60mg, I began having terrible stomach pain. A couple days later, my feet started to feel ice cold, but they were warm to the touch. I then began having trouble urinating, double vision, ringing in my ears, dizziness & severe headaches. I literally thought I was dying and close to death. My wife had looked up the possible side effects of Cymbalta I immediately called the prescribing doctor and he informed me to STOP CYMBALTA IMMEDIATELY!! I was instructed NOT TO STOP COLD TURKEY or else I could risk having life long damage from the side effects.”

1 / 10
Ogr January 9, 2021

“Horrific, didn’t fix of my Post Vasectomy pain, and while on it didn’t care about anything, like making sure the kids were fed or care about stopping for red lights or getting to work on time. But the Doctor liked me being on it because I was tired all the time and slept lots, was more docile and didn’t complain about the pain. Just try it and watch your life go down the toilet. Would be good if I was in nursing home at the end of my life but I still have a life to live (only 50 years old).”

1 / 10

More FAQ

Meg444 January 8, 2021

“Horrible Experience! Two hours after I took Cymbalta, out of no where my heart started beating so fast I thought I was having a heart attack. I couldn’t breathe. My chest and arms started burning. Heat washed over me. I had no clue what was going on. Then I remembered the Cymbalta. I panicked and ran to the bathroom to try and throw it up. It was too late. I thought it was so bad for me. I had never had a panic attack in my life. Not once. I laid on the bed and tried to control my breathing. 6 hours of panic attacks and a trip to the ER finally stopped them. Since then, I have had many more panic attacks. After one pill of Cymbalta, things that never bothered me before.. like Epinephrin in the dentist chair are suddenly causing panic attacks. This morning I woke up to a panic attack yet its been 9 months since I took it! It would seem, that Cymbalta gave me a panic disorder. I wish I had never taken it.”

1 / 10
Anonymous · Taken for 2 to 5 years December 30, 2020

“Had very severe, burning nerve pain in lower back. Had 3 hip replacements. 2 back surgeries. Knee surgery, Bypass surgery. Broken leg & ankle with screws broken shoulder & broken pelvis with screws. Prostate removal. Use of Duloxetine now 2 years. Never used pain meds at any time. On morphine drip after a surgery. Still try to be very active. Just had severe fall 20’ plus. Fall has damaged a lot of body parts again! Have extreme night sweats from Duloxetine. But feel up with plenty of energy. Nerve pain had diminished 90 %. After fall some a lot that pain has returned. Still have all the desires of life. But not unbearable Burning Nerve pain as it was before Duloxetine. Am 75, am physically strong. Need to know can I stay on Duloxetine for MANY more years?”

10 / 10
blue-sky · Taken for less than 1 month December 25, 2020

“One of the worst medications ever. 1st 5 days, had no desire to do anything. Complete apathy about everything. Also had terrible nausea for 5 days. That finally went away. Then it started feeling like something was literally tapping on my brain. It did nothing for the chronic pain I had. I don't know how anyone can take this medicine. Stopped taking it. Had a headache for a few days, that was it.”

1 / 10
Always In Pain · Taken for 1 to 6 months June 2, 2020

“Cymbalta is somewhat costly. Initially prescribed for lower back pain. The first 2-3 months, it worked VERY well. It helped with the back pain, and, improved my general mood. Bonus feature, it was helping with my permanent migraine. I had only a few side effects, at first, but, they started building up. Insomnia to the point of 15 minutes of sleep, or less, per day (for over a month), spontaneous ejaculation, cold sweats, no sex drive. Started to get a few electric shock-like sensations in the extremities. Started to feel zombie-like. I came off the stuff cold turkey. Withdrawal symptoms included MANY shock-like jolts to hands & feet (for about 6 years), a few months of a zombie-like feeling (Low drive) I'd rate it GOOD for a short-term use (1-2 months). Anything longer than 3 months, I would strongly advise against. (As any other anti-depressant)”

2 / 10
Anonymous · Taken for less than 1 month June 2, 2020

“Not good. Try to change your situation without using cymbalta. If you cannot exercise to relieve your pain then try deep breathing and relaxing music, books or walking. If you are bed ridden, pray and use mindful thinking. It requires time and dedication. Learn stretches with deep breaths but be careful to not break or injure yourself.”

1 / 10
Amira · Taken for 6 months to 1 year May 2, 2020

“Cymbalta has been the worst drug I've ever been on and was irresponsibly prescribed by my dr for chronic pain. I was on it for 4 months and it didn't work at all. To make it worse I almost died from withdrawal because my dr took off for 3 months and left no one in his place to write my prescription. Therefore I went into withdrawal, which he never warned me about. This drug is worse than any opiate. If you take your medication responsibly you shouldn't be denied other more helpful medication.”

1 / 10
popolopo · Taken for less than 1 month February 6, 2020

“Tried Cymbalta for leg pain. It helps but it is impossible to sleep so I quit.”

2 / 10
Caligrammy · Taken for less than 1 month January 15, 2020

“I have been on Cymbalta for 3 weeks and feel great — free of spine pain and aches that follow surgeries. No longer am I taking pain meds or high doses of aspirin. Keep pinching myself that this is real!”

10 / 10
GleeAgain · Taken for 2 to 5 years December 20, 2019

“This is the only med that has helped my nerve pain/neuropathy. Lyrica & Neurotin didn’t work. One made me dizzy, the other made my nerve pain worse. I was scared to try Cymbalta after hearing some people say they hated it. Honestly it’s been a Godsend for me. I still have other kinds of pain, but the pins & needles & tingling & burning are no longer there. I take a narcotic a few times a day, but 1/2 what I did before Cymbalta. I may have had some weight gain from it, but I don’t know if it’s this or just my age & diet mostly. I can’t get off the Cymbalta for now as it helps too much. I also used to have some anxiety/panic attacks & I don’t have them on this. I’m able to stop myself thank God. I have a happy sex life with my husband & no negative side effects (except possibly a few pounds). I also have low back pain less frequently. You don’t know til you try it how it might work for you. I take 60mg/night 4-5 years. I’m 45 years old.”

8 / 10
Leonela · Taken for 1 to 6 months December 7, 2019

“I have been on Cymbalta 20mg for the last 3 months for my neck pain. I am developing a skin rash in my neck. It’s itching and red. Also, little blisters too. Also, my appetite has decreased to the point that I have lost 10 pounds. My pain still the same.”

1 / 10
Izzle · Taken for 1 to 2 years December 4, 2019

“I gave it a 2 because it helped with my pain and I saw a very quick change in my anxiety. But I've lost so much sleep over the last year due to insomnia and severe night sweats, my Dr told me take it in the morning instead but since I needed help sleeping this was already doing the opposite. if I miss a single dose I get severe electric shocks starting in my head going to my feet. Burning head but freezing extremities, shakes, nausea and that's the physical symptoms. Mentally I would be wailing and almost hitting my head against a wall begging whatever was going on to stop. I tried going off it cold turkey after a year on 60mg and the physical and mental pain is what I'd imagine heroin withdrawal to be. Now my dosage is halved my chronic pain is back with a vengeance so it was working for my pain but I feel pushing through the pain from the get go would have been easier than going through the side effects of this medication for a year. Be warned this drug is for life.”

2 / 10
Poggy · Taken for 1 to 6 months November 23, 2019

“I feel this has helped my back pain but possible side effect are loose bowels loss of appetite and lost weight. Not sure if should continue”

6 / 10
Maggsoct October 18, 2019

“I am taking the time to write a positive review for Cymbalta to hopefully help another person considering this medication. Dose and Side effects -> My experience has been good with brand version of Cymbalta for 1 month - 30 mg. Day 1 a bit nauseous and diarrhea. Nothing else except constipation. Relief-> I suffer from nerve / chronic pain. I felt relief from back pain week 1 and at week 3 my nerve pain is calming down. I have not gained weight. Cymbalta->For those considering this medication, take time to read the good reviews and consider the brand version if you can afford it. Generics aren’t the exact replicas of the original brand. There are umpteen different versions of generics and vary from pharmacy to pharmacy. So you never know what kind you're going to get. Take time to do your research -> I work in medical education. The information is out there on the net to educate us on side effects, generics, withdrawal etc.”

9 / 10
Beau58 · Taken for 1 to 6 months October 10, 2019

“I can't even tell I'm taking anything, and I am taking 60 mg doses”

1 / 10
Neenah · Taken for 6 months to 1 year October 9, 2019

“This drug made me so depressed to the point of having suicidal thoughts. When I finally realized that it was causing this, the withdrawal symptoms are worse than anything I've ever experienced. Anxiety, extreme nausea, intense vertigo, muscle spasms. Do not take this drug, there's so many better options.”

1 / 10
Swampy October 6, 2019

“I was given duloxetine to help with depression and pain after I revealed to my psych that I feel random aches and pains nearly all the time. First day taking it was hard - terrible stomach pain and diarrhea. But, after that my tummy settled. I am at 90mg and I no longer notice these random pains that I got for no reason. It's great to be comfortable. I cannot comment as to whether it helps with my depression as I take a few different meds for that.”

10 / 10
Grandma Pat · Taken for 1 to 6 months September 30, 2019

“I was prescribed Cymbalta at 20 mg for pain following hip replacement. It didn’t help with pain, but I was sleeping so well that I kept taking it. Then the nightmares started and kept getting worse. I finally stopped taking the drug on my own after 4 months. The nightmares have stopped. But, surprisingly, my blood sugar which has been steadily climbing toward 200 is now back near 100. No change to anything else. I can only attribute this to the discontinuation of Cymbalta. And I feel much better.”

5 / 10
CieBarbie · Taken for 5 to 10 years September 24, 2019

“I have rheumatoid arthritis that was not responding to orencia, arava, rituxan (!), cimzia or humira. Prior to these medications, I was on enbrel, but it stopped working after 9 years and I was allergic to methotrexate. The cymbalta seemed to make my pain much more bearable. I still had the joint pains, but somehow, the pain wasn't such a massive ordeal. Oh, and it also nicely treated my chronic major depressive disorder as well. I thought that maybe if I was on a higher dose, I might have less pain, so my dose of generic (Lupin) duloxetine was increased up to 150mg a day, and I found that although I could function fine during the day, I could not sleep. It was like I was too keyed up or something. Not anxious, just keyed up. I was able to sleep once I dropped my dose back down to 120mg a day. I give Cymbalta a 10 because it is a single medicine that treats two medical conditions!”

10 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.