Cymbalta Alternatives Compared
Cymbalta (duloxetine) | Auvelity (bupropion / dextromethorphan) | Vraylar (cariprazine) |
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Cymbalta (duloxetine) | Auvelity (bupropion / dextromethorphan) | Vraylar (cariprazine) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Auvelity is an oral combination antidepressant tablet containing bupropion and dextromethorphan that has a novel way of working to treat adults with severe depression. Research has shown it is... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Related suggestions Major Depressive Disorder
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More about Cymbalta (duloxetine) | More about Auvelity (bupropion / dextromethorphan) | More about Vraylar (cariprazine) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Cymbalta has an average rating of 6.3 out of 10 from a total of 1904 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Auvelity has an average rating of 8.5 out of 10 from a total of 145 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 527 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Cymbalta side effects |
View all Auvelity side effects |
View all Vraylar side effects |
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Drug Class | ||||||||||||||||||||||||||
Generic Availability | ||||||||||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Cymbalta prices |
View all Auvelity prices |
View all Vraylar prices |
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Dosage Forms | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
N/A |
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Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
17 hours |
30 hours |
504 hours |
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CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 633 drugs are known to interact with Cymbalta:
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A total of 697 drugs are known to interact with Auvelity:
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A total of 578 drugs are known to interact with Vraylar:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
N/A |
August 18, 2022 |
September 17, 2015 |
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WADA Class View classifications | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient Resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Auvelity
Auvelity (dextromethorphan and bupropion) is used to treat major depressive disorder. Includes ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Tylenol
Tylenol is a pain reliever and a fever reducer used to treat many conditions such as headaches ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Oxycodone
Oxycodone is an opioid analgesic used to treat moderate to severe pain; it has a high potential for ...
Venlafaxine
Venlafaxine is used to treat major depressive disorder, anxiety, and panic disorder. Learn about ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.