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Medications for Smoking Cessation

About Smoking Cessation:  Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke.

Drugs Used for Smoking Cessation

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Chantix C N X 1020 reviews
8.0

Generic name: varenicline systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

bupropion C N X 227 reviews
8.0

Generic name: bupropion systemic

Brand names:  Zyban, Buproban

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Zyban C N X 92 reviews
8.0

Generic name: bupropion systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

nicotine D N 135 reviews
8.0

Generic name: nicotine systemic

Brand names:  Nicoderm CQ, Habitrol, Nicorette, Nicotrol Inhaler, Nicotrol NS, Commit, Leader Nicotine Polacrilex, Nicorelief …show all

Drug class: smoking cessation agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Topamax Off Label D N X 2 reviews
2.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

Buproban C N X 5 reviews
7.0

Generic name: bupropion systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Nicoderm CQ D N 52 reviews
9.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

varenicline C N X 1297 reviews
8.0

Generic name: varenicline systemic

Brand name:  Chantix

Drug class: smoking cessation agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Habitrol D N 6 reviews
8.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Nicorette D N 16 reviews
7.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

clonidine Off Label C N X Add review
10

Generic name: clonidine systemic

Drug class: antiadrenergic agents, centrally acting

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Nicotrol Inhaler D N 25 reviews
8.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

topiramate Off Label D N X 3 reviews
2.0

Generic name: topiramate systemic

Brand names:  Topamax, Topamax Sprinkle, Topiragen

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Nicotrol NS D N 3 reviews
6.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Topamax Sprinkle Off Label D N X Add review Rate

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

Off Label: Yes

Topiragen Off Label D N X Add review Rate

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

Commit D N 17 reviews
8.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Leader Nicotine Polacrilex D N 1 review
5.0

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

naltrexone Off Label C N X Add review Rate

Generic name: naltrexone systemic

Drug class: antidotes, drugs used in alcohol dependence

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

nortriptyline Off Label N N X 6 reviews
9.0

Generic name: nortriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Nicorelief D N Add review Rate

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Alternative treatments for Smoking Cessation

The following products are considered to be alternative treatments or natural remedies for Smoking Cessation. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Smoking Cessation.

Learn more about Smoking Cessation

Drugs.com Health Center

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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