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Medications for Smoking Cessation

About Smoking Cessation

Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke.

Drugs used for Smoking Cessation

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Chantix 8.6 1169 reviews
Rx C N X

Generic name: varenicline systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

bupropion 8.1 289 reviews
Rx C N X

Generic name: bupropion systemic

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

topiramate Off-label 5.0 4 reviews
Rx D N X

Generic name: topiramate systemic

Brand name:  Topamax

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

naltrexone Off-label 0.0 1 review
Rx C N X

Generic name: naltrexone systemic

Drug class: antidotes, drugs used in alcohol dependence

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

nicotine 7.8 177 reviews
Rx/OTC D N

Generic name: nicotine systemic

Brand names:  Nicoderm CQ, Habitrol, Nicorette, Nicotrol Inhaler, Commit, Leader Nicotine Polacrilex, Nicotrol NS …show all

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Topamax Off-label 5.0 3 reviews
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Nicoderm CQ 9.0 58 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

varenicline 8.6 1590 reviews
Rx C N X

Generic name: varenicline systemic

Brand name:  Chantix

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

clonidine Off-label Rate Add review
Rx C N X

Generic name: clonidine systemic

Drug class: antiadrenergic agents, centrally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Habitrol 6.4 8 reviews
OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Nicorette 6.6 33 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Nicotrol Inhaler 7.7 34 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

nortriptyline Off-label 9.5 6 reviews
Rx N N X

Generic name: nortriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Commit 8.9 17 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Leader Nicotine Polacrilex 5.7 3 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

Nicotrol NS 5.8 5 reviews
Rx/OTC D N

Generic name: nicotine systemic

Drug class: smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Alternative treatments for Smoking Cessation

The following products are considered to be alternative treatments or natural remedies for Smoking Cessation. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Smoking Cessation.

Learn more about Smoking Cessation

Drugs.com Health Center

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.