Naltrexone Interactions
There are 352 drugs known to interact with naltrexone, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 34 are major, and 318 are moderate.
- View all 352 medications that may interact with naltrexone
- View naltrexone alcohol/food interactions (1)
- View naltrexone disease interactions (2)
Most frequently checked interactions
View interaction reports for naltrexone and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Ozempic (semaglutide)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin (bupropion)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Naltrexone alcohol/food interactions
There is 1 alcohol/food interaction with naltrexone.
Naltrexone disease interactions
There are 2 disease interactions with naltrexone which include:
Report options
More about naltrexone
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- Latest FDA alerts (1)
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- Patient tips
- During pregnancy
- Support group
- Drug class: antidotes
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
