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Naltrexone Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Naltrexone Remove Naltrexone from your drug comparison Vivitrol Remove Vivitrol from your drug comparison Antabuse Remove Antabuse from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Naltrexone Remove Naltrexone from your drug comparison Vivitrol naltrexone Remove Vivitrol from your drug comparison Antabuse disulfiram Remove Antabuse from your drug comparison

Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction. People taking naltrexone need to have completely stopped taking all types of opioids... View more

Vivitrol is used as an adjunct to social and psychotherapy in the treatment of alcohol addiction that is given by intramuscular injection by a health professional once every four weeks. People taking... View more

Prescribed for Alcohol Dependence. Antabuse may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Prescription only

Ratings & Reviews

View all 467 reviews

View all 167 reviews

View all 92 reviews

Drug Class

Side Effects

Commonly reported side effects include: streptococcal pharyngitis, syncope, anxiety, arthralgia, arthritis, dizziness, drowsiness, fatigue, frequent headaches, headache, joint stiffness, nasopharyngitis, nausea, nervousness, obsessive compulsive disorder, panic attack, pharyngitis, posttraumatic stress disorder, sedated state, sinus headache, vomiting, induration at injection site, malaise, pain at injection site, tenderness at injection site.

See the full naltrexone side effects document.

Common side effects include: streptococcal pharyngitis, syncope, anxiety, arthralgia, arthritis, dizziness, drowsiness, fatigue, frequent headaches, headache, joint stiffness, nasopharyngitis, nausea, nervousness, obsessive compulsive disorder, panic attack, pharyngitis, posttraumatic stress disorder, sedated state, sinus headache, vomiting, induration at injection site, malaise, pain at injection site, tenderness at injection site.

See the full Vivitrol side effects document.

See the full Antabuse side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 each
Dosage 50 mg
Per Unit* $1.82 - $2.23
Cost* $54.48 - $66.96

View all naltrexone prices

Quantity 1 powder for injection, extended release
Dosage 380 mg
Per Unit* $1,458.09
Cost* $1,458.09

View all Vivitrol prices and generic prices

Quantity 10 tablet
Dosage 250 mg
Per Unit* $4.57
Cost* $45.67

View all Antabuse prices and generic prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes

Yes

Dosage Form(s) Available
  • Oral tablet
  • Intramuscular powder for injection, extended release
  • Oral tablet

Brand Names
Vivitrol

N/A

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

10 hours

10 hours

7 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (3)

N/A

Drug Interactions

A total of 311 drugs are known to interact with naltrexone:

  • 33 major drug interactions (157 brand and generic names)
  • 278 moderate drug interactions (1200 brand and generic names)

A total of 311 drugs are known to interact with Vivitrol:

  • 33 major drug interactions (157 brand and generic names)
  • 278 moderate drug interactions (1200 brand and generic names)

A total of 173 drugs are known to interact with Antabuse:

  • 14 major drug interactions (40 brand and generic names)
  • 144 moderate drug interactions (440 brand and generic names)
  • 15 minor drug interactions (68 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Naltrexone may cause liver problems, and using it with other medications that can also affect the... View more
  • Naltrexone may cause liver problems, and using it with other medications that can also affect the... View more
  • You should not drink alcoholic beverages or use medicines that contain alcohol during treatment... View more

Disease Interactions

First Approval Date

April 13, 2006

April 13, 2006

August 28, 1951

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer