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Acamprosate Dosage

Medically reviewed by Last updated on May 28, 2024.

Applies to the following strengths: 333 mg

Usual Adult Dose for Alcohol Dependence

666 mg orally 3 times a day


Use: For the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation

Renal Dose Adjustments

Mild renal dysfunction (CrCl greater than 50 mL/min): Data not available

Moderate renal dysfunction (CrCl 30 to 50 mL/min):

Severe renal dysfunction (CrCl 30 mL/min and less): Contraindicated

Liver Dose Adjustments

Mild to moderate liver dysfunction (Child-Pugh Classes A and B): No adjustment recommended.
Severe liver dysfunction (Child-Pugh Class C): Data not available



Safety and efficacy have not been established in pediatric patients.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:



Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.