Generic name: naltrexone (oral) [ nal-TREX-own ]
Drug classes: Antidotes, Drugs used in alcohol dependence

Medically reviewed by Drugs.com on Feb 9, 2024. Written by Cerner Multum.

What is ReVia?

ReVia is used in adults to treat alcohol dependence and block the effects of opioids.

ReVia may also be used for purposes not listed in this medication guide.

ReVia side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Using opioid medicine while you are taking ReVia could stimulate opioid withdrawal symptoms. Common withdrawal symptoms are craving for opioids, sweating, fever, stomach pain, vomiting, diarrhea, watery eyes, runny or stuffy nose, tingling, goose bumps, body aches, shaking, muscle twitching, trouble sleeping, and feeling anxious, depressed, fearful, restless or uneasy.

ReVia may cause serious side effects. Call your doctor at once if you have:

• severe nausea, vomiting, or diarrhea;

• confusion, mood changes, crying, hallucinations; or

• depression, thoughts about suicide or hurting yourself.

High doses of naltrexone oral may harm your liver. Stop taking ReVia and call your doctor at once if you have right-sided upper stomach pain, vomiting, loss of appetite, dark urine, clay-colored stools, or yellowing of your skin or eyes.

Common side effects of ReVia may include:

• nausea, vomiting, stomach pain;

• headache, dizziness, drowsiness;

• feeling anxious or nervous;

• sleep problems (insomnia); or

• muscle or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

You should not be treated with ReVia if you are currently using an opioid analgesic, are addicted to opioids or having opioid withdrawal symptoms, or if you have used any opioid medicine such as, methadone, buprenorphine, tramadol, and others opioids within 7 to 14 days.

You should not use ReVia if you have failed the naloxone challenge test or have tested positive for the urine screen for opioids.

Before taking this medicine

You should not use ReVia if you are allergic to it, or if:

• you are currently addicted to opioids;

• you are having withdrawal symptoms from opioid addiction;

• you are using any opioid pain medicine (including fentanyl, Vicodin, OxyContin, and many others);

• you have failed the naloxone challenge test or have a positive urine screen for opioids; or

• you have used any opioid medicine such as, methadone, buprenorphine, tramadol, and others opioids within 7 to 14 days.

Tell your doctor if you use thioridazine or disulfiram.

Also tell your doctor if you have or have ever had:

• liver or kidney disease.

It is not known if ReVia will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using ReVia.

How should I take ReVia?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Your doctor may recommend you have a family member or other caregiver make sure you take ReVia on schedule, to make sure you are using the medicine correctly as part of your treatment.

Wear a medical alert tag or carry an ID card to let others know you use ReVia.

ReVia is only part of a complete treatment program that may also include additional forms of counseling and/or monitoring. Follow your doctor's instructions very carefully.

Store tightly closed at room temperature, away from moisture and heat. Protect from light.

After taking ReVia, your body will be more sensitive to opioids. If you use an opioid medicine in the future, you will need to use less than before the this medicine treatment. Using the same amount you used before could lead to overdose or death.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking ReVia?

Do not use opioid medication, heroin, or other street drugs while you are taking ReVia. Never try to overcome the effects of naltrexone by taking larger amounts of opioids. Doing so could result in dangerous effects, including coma or death.

Ask your doctor before using any medicine to treat a cold, cough, diarrhea, or pain. These medicines may contain opioids and may not work as well while you are taking ReVia.

ReVia may cause dizziness or drowsiness and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

What other drugs will affect ReVia?

Other drugs may affect ReVia, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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