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OxyContin

Pronunciation

Generic Name: oxycodone (ox i KOE done)
Brand Names: Oxaydo, OxyContin, Oxyfast, Roxicodone, Xtampza ER

What is OxyContin?

OxyContin (oxycodone) is an opioid pain medication. An opioid is sometimes called a narcotic.

OxyContin is used to treat moderate to severe pain that is expected to last for an extended period of time. OxyContin is used for around-the-clock treatment of pain. It is not to be used on an "as-needed" basis for pain.

OxyContin may also be used for purposes not listed in this medication guide.

Important information

You should not use OxyContin if you have severe asthma or breathing problems, or a blockage in your stomach or intestines.

Oxycodone can slow or stop your breathing.

Oxycodone may be habit-forming, even at regular doses. Take this medicine exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

Before taking this medicine

You should not use OxyContin if you are allergic to oxycodone, or if you have:

  • severe asthma or breathing problems; or

  • a blockage in your stomach or intestines.

You should not use OxyContin unless you are already using a similar opioid medicine and are tolerant to it.

OxyContin should not be given to a child younger than 11 years old.

To make sure OxyContin is safe for you, tell your doctor if you have:

  • a history of head injury, brain tumor, or seizures;

  • a history of drug abuse, alcohol addiction, or mental illness;

  • urination problems;

  • liver or kidney disease;

  • problems with your gallbladder, pancreas, or thyroid; or

  • if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).

If you use OxyContin while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Do not breast-feed. Oxycodone can pass into breast milk and may cause drowsiness or breathing problems in a nursing baby.

How should I use OxyContin?

Take OxyContin exactly as prescribed. Follow all directions on your prescription label. OxyContin can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take OxyContin in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

OxyContin may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away OxyContin is against the law.

Stop taking all other around-the-clock narcotic pain medicines when you start taking extended-release OxyContin..

Take with food.

Do not crush, break, or open an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.

You should not stop using oxycodone suddenly. Follow your doctor's instructions about tapering your dose.

Never crush or break a tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This can cause in death.

Store at room temperature, away from heat, moisture, and light.

Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Do not keep leftover OxyContin tablets. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush any unused tablets down the toilet.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Since OxyContin is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An oxycodone overdose can be fatal, especially in a child or other person using the medicine without a prescription.

Overdose symptoms may include slow heartbeats, severe muscle weakness, cold and clammy skin, noisy breathing, and very slow breathing.

What should I avoid while using OxyContin?

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or operating machinery until you know how OxyContin will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Avoid medication errors. Always check the brand and strength of oxycodone you get from the pharmacy.

OxyContin side effects

Get emergency medical help if you have signs of an allergic reaction to OxyContin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medicines, oxycodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, pinpoint pupils, or if you are hard to wake up.

Call your doctor at once if you have:

  • shallow breathing, slow heartbeats;

  • confusion, severe drowsiness, seizure (convulsions);

  • severe constipation;

  • missed menstrual periods;

  • impotence, sexual problems, loss of interest in sex;

  • a light-headed feeling, like you might pass out; or

  • low cortisol levels - nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.

Serious side effects may be more likely in older adults and those who are malnourished or debilitated.

Common OxyContin side effects may include:

  • drowsiness, headache, dizziness, tired feeling; or

  • constipation, stomach pain, nausea, vomiting, loss of appetite.

  • dry mouth; or

  • mild itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Oxycodone dosing information

Usual Adult Dose for Pain:

Initial:
Controlled Release (CR): 10 mg orally every 12 hours.

Maintenance:
CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require "as needed" rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

Usual Geriatric Dose for Pain:

Initial:
Immediate Release (IR): 2.5 mg orally every 6 hours

Maintenance:
CR: 20 mg to 640 mg per day in patients with cancer pain. The average total daily dose is approximately 105 mg per day. Cancer patients with severe pain may require "as needed" rescue doses of the immediate-release form of oxycodone to supplement the controlled-release form.

What other drugs will affect OxyContin?

Some drugs can raise or lower your blood levels of oxycodone, which may cause side effects or make OxyContin less effective. Tell your doctor if you also use certain antibiotics, antifungal medications, heart or blood pressure medications, or medicines to treat HIV or AIDS.

Narcotic (opioid) medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • other narcotic medications - opioid pain medicine or prescription cough medicine;

  • drugs that make you sleepy or slow your breathing - a sleeping pill, muscle relaxer, sedative, tranquilizer, or antipsychotic medicine; or

  • drugs that affect serotonin levels in your body - medicine for depression, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

This list is not complete. Other drugs may interact with oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your pharmacist can provide more information about OxyContin.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use OxyContin only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2017 Cerner Multum, Inc. Version: 11.01.

Date modified: June 11, 2017
Last reviewed: May 05, 2017

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