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Narcotic analgesics

Other names: narcotics, opiates, opioid analgesics

What are Narcotic analgesics

Narcotic analgesics (also called opiates, opioid analgesics, or narcotics) are a group of medicines that relieve acute and chronic severe pain by binding to opioid receptors. There are at least four opioid receptors: mu, delta, kappa and opioid receptor like-1 (ORL1) receptor. These influence the opioid system which controls pain, reward and addictive behaviors. Opioid receptors are most abundant in the brain but are also found elsewhere in the body, including the digestive tract, respiratory tract and spinal cord.

Pleasurable activities (such as laughing and loving) release natural endorphins, dynorphins, and enkephalins which activate opioid receptors, improving our mood. Opioid receptors can also be activated by exogenous compounds, for example narcotic analgesics. Most narcotic analgesics act on the mu receptor and are very effective at relieving pain, but unfortunately, also activate reward pathways meaning that narcotic analgesics have a tendency to cause addiction, dependence and tolerance (where increasing dosages are needed to provide the same pain-relieving effect). Morphine and codeine are alkaloid opiates because they occur naturally. Heroin, hydrocodone, hydromorphone, oxycodone and oxymorphone are semi-synthetic because they are made by modifying morphine.

Common side effects of opiates include constipation, itch, low blood pressure, miosis (excessive constriction of the pupil of the eye), nausea, sedation, urinary retention, and respiratory depression. Most are also effective at suppressing the urge to cough. Different narcotic analgesics have different potencies, based on how strongly they bind to the opioid receptor, meaning dosages vary considerably from one narcotic to the next (for example, fentanyl is 80 to 100 times stronger than morphine).

List of Narcotic analgesics:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Astramorph PF (Pro, More...)
generic name: morphine
0 reviews
   
10
Dazidox (More...)
generic name: oxycodone
1 review
   
10
Ionsys (Pro, More...)
generic name: fentanyl
0 reviews
   
10
Lazanda (Pro, More...)
generic name: fentanyl
1 review
   
10
Numorphan (Pro, More...)
generic name: oxymorphone
0 reviews
   
10
Onsolis (Pro, More...)
generic name: fentanyl
0 reviews
   
10
Oxyfast (More...)
generic name: oxycodone
4 reviews
   
10
Palladone (Pro, More...)
generic name: hydromorphone
1 review
   
10
Roxanol (More...)
generic name: morphine
0 reviews
   
10
Roxanol-T (More...)
generic name: morphine
0 reviews
   
10
Roxicodone Intensol (More...)
generic name: oxycodone
5 reviews
   
10
Meperitab (More...)
generic name: meperidine
3 reviews
   
9.8
Methadone Diskets (More...)
generic name: methadone
29 reviews
   
9.4
Fentora (Pro, More...)
generic name: fentanyl
13 reviews
   
9.3
Actiq (Pro, More...)
generic name: fentanyl
16 reviews
   
9.2
Subutex (More...)
generic name: buprenorphine
83 reviews
   
9.2
Demerol (Pro, More...)
generic name: meperidine
59 reviews
   
9.1
Dolophine (Pro, More...)
generic name: methadone
21 reviews
   
9.1
Infumorph (Pro, More...)
generic name: morphine
2 reviews
   
9.0
Opium Deodorized (More...)
generic name: opium
2 reviews
   
9.0
Roxicodone (Pro, More...)
generic name: oxycodone
56 reviews
   
9.0
Methadose (Pro, More...)
generic name: methadone
34 reviews
   
8.9
Paregoric (More...)
generic name: opium
8 reviews
   
8.7
OxyContin (Pro, More...)
generic name: oxycodone
261 reviews
   
8.6
Subsys (Pro, More...)
generic name: fentanyl
12 reviews
   
8.6
Dilaudid (Pro, More...)
generic name: hydromorphone
275 reviews
   
8.5
Oxydose (More...)
generic name: oxycodone
1 review
   
8.5
Zohydro ER (More...)
generic name: hydrocodone
39 reviews
   
8.4
Buprenex (Pro, More...)
generic name: buprenorphine
4 reviews
   
8.3
Duragesic (Pro, More...)
generic name: fentanyl
70 reviews
   
8.3
Kadian (Pro, More...)
generic name: morphine
45 reviews
   
8.2
Opana (Pro, More...)
generic name: oxymorphone
88 reviews
   
8.1
Sublimaze (Pro, More...)
generic name: fentanyl
6 reviews
   
8.1
MS Contin (Pro, More...)
generic name: morphine
86 reviews
   
8.0
Ultram ODT (More...)
generic name: tramadol
10 reviews
   
8.0
Avinza (Pro, More...)
generic name: morphine
32 reviews
   
7.9
Fentanyl Transdermal System (More...)
generic name: fentanyl
68 reviews
   
7.9
Dilaudid-HP (Pro, More...)
generic name: hydromorphone
8 reviews
   
7.8
Exalgo (Pro, More...)
generic name: hydromorphone
33 reviews
   
7.8
Levo-Dromoran (Pro, More...)
generic name: levorphanol
3 reviews
   
7.8
OxyIR (More...)
generic name: oxycodone
4 reviews
   
7.8
Stadol (Pro, More...)
generic name: butorphanol
39 reviews
   
7.8
Nubain (Pro, More...)
generic name: nalbuphine
23 reviews
   
7.7
Opana ER (Pro, More...)
generic name: oxymorphone
83 reviews
   
7.7
Abstral (Pro, More...)
generic name: fentanyl
2 reviews
   
7.6
Rybix ODT (Pro, More...)
generic name: tramadol
0 reviews
   
7.5
Ultram ER (Pro, More...)
generic name: tramadol
32 reviews
   
7.5
Nucynta ER (Pro, More...)
generic name: tapentadol
57 reviews
   
7.4
Darvon (More...)
generic name: propoxyphene
7 reviews
   
7.2
Butrans (Pro, More...)
generic name: buprenorphine
154 reviews
   
6.8
Oramorph SR (Pro, More...)
generic name: morphine
4 reviews
   
6.8
Nucynta (Pro, More...)
generic name: tapentadol
218 reviews
   
6.5
Ultram (Pro, More...)
generic name: tramadol
206 reviews
   
6.4
Duramorph (Pro, More...)
generic name: morphine
4 reviews
   
6.2
Ryzolt (Pro, More...)
generic name: tramadol
11 reviews
   
6.2
Xtampza ER (Pro, More...)
generic name: oxycodone
16 reviews
   
5.7
Alfenta (More...)
generic name: alfentanil
0 reviews
   
5.5
Talwin (More...)
generic name: pentazocine
6 reviews
   
5.3
ConZip (Pro, More...)
generic name: tramadol
1 review
   
5.2
Hysingla ER (Pro, More...)
generic name: hydrocodone
58 reviews
   
4.3
Belbuca (Pro, More...)
generic name: buprenorphine
52 reviews
   
3.7
Oxaydo (Pro, More...)
generic name: oxycodone
3 reviews
   
3.3
Arymo ER (Pro, More...)
generic name: morphine
0 reviewsAdd rating
DepoDur (More...)
generic name: morphine liposomal
0 reviewsAdd rating
ETH-Oxydose (More...)
generic name: oxycodone
0 reviewsAdd rating
Methadose Sugar-Free (More...)
generic name: methadone
0 reviewsAdd rating
MorphaBond ER (Pro, More...)
generic name: morphine
0 reviewsAdd rating
Oxecta (Pro, More...)
generic name: oxycodone
0 reviewsAdd rating
Probuphine (Pro, More...)
generic name: buprenorphine
0 reviewsAdd rating
RMS (More...)
generic name: morphine
0 reviewsAdd rating
RoxyBond (Pro, More...)
generic name: oxycodone
0 reviewsAdd rating
Sufenta (Pro, More...)
generic name: sufentanil
0 reviewsAdd rating
Ultiva (Pro, More...)
generic name: remifentanil
0 reviewsAdd rating
Vantrela ER (More...)
generic name: hydrocodone
0 reviewsAdd rating
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