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Narcotic analgesics

What are Narcotic analgesics

Narcotic analgesics (also called opiates, opioid analgesics, or narcotics) are a group of medicines that relieve acute and chronic severe pain by binding to opioid receptors. There are at least four opioid receptors: mu, delta, kappa and opioid receptor like-1 (ORL1) receptor. These influence the opioid system which controls pain, reward and addictive behaviors. Opioid receptors are most abundant in the brain but are also found elsewhere in the body, including the digestive tract, respiratory tract and spinal cord.

Pleasurable activities (such as laughing and loving) release natural endorphins, dynorphins, and enkephalins which activate opioid receptors, improving our mood. Opioid receptors can also be activated by exogenous compounds, for example narcotic analgesics. Most narcotic analgesics act on the mu receptor and are very effective at relieving pain, but unfortunately, also activate reward pathways meaning that narcotic analgesics have a tendency to cause addiction, dependence and tolerance (where increasing dosages are needed to provide the same pain-relieving effect). Morphine and codeine are alkaloid opiates because they occur naturally. Heroin, hydrocodone, hydromorphone, oxycodone and oxymorphone are semi-synthetic because they are made by modifying morphine.

Common side effects of opiates include constipation, itch, low blood pressure, miosis (excessive constriction of the pupil of the eye), nausea, sedation, urinary retention, and respiratory depression. Most are also effective at suppressing the urge to cough. Different narcotic analgesics have different potencies, based on how strongly they bind to the opioid receptor, meaning dosages vary considerably from one narcotic to the next (for example, fentanyl is 80 to 100 times stronger than morphine).

List of Narcotic analgesics:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Astramorph PF (Pro, More...)
generic name: morphine
0 reviews
   
10
Ionsys (Pro, More...)
generic name: fentanyl
0 reviews
   
10
Lazanda (Pro, More...)
generic name: fentanyl
1 review
   
10
Numorphan (Pro, More...)
generic name: oxymorphone
0 reviews
   
10
Onsolis (Pro, More...)
generic name: fentanyl
0 reviews
   
10
Oxyfast (More...)
generic name: oxycodone
4 reviews
   
10
Palladone (Pro, More...)
generic name: hydromorphone
1 review
   
10
Roxanol (More...)
generic name: morphine
0 reviews
   
10
Roxanol-T (More...)
generic name: morphine
0 reviews
   
10
Roxicodone Intensol (More...)
generic name: oxycodone
5 reviews
   
10
Meperitab (More...)
generic name: meperidine
3 reviews
   
9.8
Methadone Diskets (More...)
generic name: methadone
27 reviews
   
9.4
Fentora (Pro, More...)
generic name: fentanyl
13 reviews
   
9.3
Actiq (Pro, More...)
generic name: fentanyl
16 reviews
   
9.2
Dolophine (Pro, More...)
generic name: methadone
19 reviews
   
9.2
Subutex (More...)
generic name: buprenorphine
82 reviews
   
9.2
Demerol (Pro, More...)
generic name: meperidine
58 reviews
   
9.1
Infumorph (Pro, More...)
generic name: morphine
2 reviews
   
9.0
Methadose (Pro, More...)
generic name: methadone
33 reviews
   
9.0
Roxicodone (Pro, More...)
generic name: oxycodone
54 reviews
   
9.0
Ultram ODT (More...)
generic name: tramadol
8 reviews
   
8.8
MSIR (More...)
generic name: morphine
2 reviews
   
8.7
OxyContin (Pro, More...)
generic name: oxycodone
259 reviews
   
8.7
Paregoric (More...)
generic name: opium
7 reviews
   
8.7
Dilaudid (Pro, More...)
generic name: hydromorphone
265 reviews
   
8.6
Duragesic-100 (More...)
generic name: fentanyl
11 reviews
   
8.6
Subsys (Pro, More...)
generic name: fentanyl
12 reviews
   
8.6
Duragesic-50 (More...)
generic name: fentanyl
10 reviews
   
8.5
Opium Deodorized (More...)
generic name: opium
1 review
   
8.5
Oxydose (More...)
generic name: oxycodone
1 review
   
8.5
Duragesic (Pro, More...)
generic name: fentanyl
34 reviews
   
8.4
Zohydro ER (More...)
generic name: hydrocodone
31 reviews
   
8.4
Buprenex (Pro, More...)
generic name: buprenorphine
4 reviews
   
8.3
Duragesic-75 (More...)
generic name: fentanyl
8 reviews
   
8.2
Kadian (Pro, More...)
generic name: morphine
44 reviews
   
8.2
Stadol (Pro, More...)
generic name: butorphanol
35 reviews
   
8.2
MS Contin (Pro, More...)
generic name: morphine
80 reviews
   
8.1
Opana (Pro, More...)
generic name: oxymorphone
87 reviews
   
8.1
Sublimaze (Pro, More...)
generic name: fentanyl
6 reviews
   
8.1
Avinza (Pro, More...)
generic name: morphine
32 reviews
   
7.9
Duragesic-25 (More...)
generic name: fentanyl
5 reviews
   
7.9
Exalgo (Pro, More...)
generic name: hydromorphone
32 reviews
   
7.9
Darvon-N (More...)
generic name: propoxyphene
3 reviews
   
7.8
Levo-Dromoran (Pro, More...)
generic name: levorphanol
3 reviews
   
7.8
Opana ER (Pro, More...)
generic name: oxymorphone
79 reviews
   
7.8
OxyIR (More...)
generic name: oxycodone
4 reviews
   
7.8
Nubain (Pro, More...)
generic name: nalbuphine
22 reviews
   
7.7
Abstral (Pro, More...)
generic name: fentanyl
2 reviews
   
7.6
Dilaudid-HP (Pro, More...)
generic name: hydromorphone
7 reviews
   
7.5
Nucynta ER (Pro, More...)
generic name: tapentadol
51 reviews
   
7.5
Rybix ODT (Pro, More...)
generic name: tramadol
0 reviews
   
7.5
Ultram ER (Pro, More...)
generic name: tramadol
30 reviews
   
7.5
Darvon (Pro, More...)
generic name: propoxyphene
6 reviews
   
7.1
Oramorph SR (Pro, More...)
generic name: morphine
3 reviews
   
6.9
Butrans (Pro, More...)
generic name: buprenorphine
148 reviews
   
6.8
Nucynta (Pro, More...)
generic name: tapentadol
207 reviews
   
6.5
Ultram (Pro, More...)
generic name: tramadol
204 reviews
   
6.4
Duramorph (Pro, More...)
generic name: morphine
4 reviews
   
6.2
Ryzolt (Pro, More...)
generic name: tramadol
11 reviews
   
6.2
Duragesic-12 (More...)
generic name: fentanyl
1 review
   
5.7
Alfenta (More...)
generic name: alfentanil
0 reviews
   
5.5
Talwin (More...)
generic name: pentazocine
6 reviews
   
5.3
ConZip (Pro, More...)
generic name: tramadol
1 review
   
5.2
Hysingla ER (Pro, More...)
generic name: hydrocodone
49 reviews
   
4.6
Belbuca (Pro, More...)
generic name: buprenorphine
45 reviews
   
3.8
Oxaydo (Pro, More...)
generic name: oxycodone
3 reviews
   
3.3
Xtampza ER (Pro, More...)
generic name: oxycodone
6 reviews
   
2.8
Arymo ER (More...)
generic name: morphine
0 reviews
   
0.0
Dazidox (More...)
generic name: oxycodone
0 reviews
   
0.0
DepoDur (More...)
generic name: morphine liposomal
0 reviews
   
0.0
ETH-Oxydose (More...)
generic name: oxycodone
0 reviews
   
0.0
Methadose Sugar-Free (More...)
generic name: methadone
0 reviews
   
0.0
MorphaBond (Pro, More...)
generic name: morphine
0 reviews
   
0.0
Oxecta (Pro, More...)
generic name: oxycodone
0 reviews
   
0.0
Probuphine (Pro, More...)
generic name: buprenorphine
0 reviews
   
0.0
RMS (More...)
generic name: morphine
0 reviews
   
0.0
Sufenta (Pro, More...)
generic name: sufentanil
0 reviews
   
0.0
Ultiva (Pro, More...)
generic name: remifentanil
0 reviews
   
0.0
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