Nalbuphine User Reviews & Ratings

Nalbuphine has an average rating of 7.5 out of 10 from a total of 34 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 24% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Pain	7.4	33 reviews for Pain	1138 medications
Anesthesia	10.0	1 reviews for Anesthesia	124 medications
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Reviews for Nalbuphine

Anonymous
Taken for 2 to 5 years
October 27, 2012

Nubain (nalbuphine) for Pain "I have chronic cervical stenosis & degenerative joint disease. All the opiates (Vicodin, Percocet, etc.) make me dizzy with unfavorable reactions. I have been on Nubain for over 2 years & never had to increase the dose. I can now be fully productive at work, it does not make me dizzy & has has no addictive feelings."

10 / 10

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22 Report

Jeano...
June 1, 2011

Nubain (nalbuphine) for Pain "I have been taking Nubain 2x a day for 11 years without ever needing to increase my dosage except for during hospital stays. I take it IV with Phenergan and it has allowed me to work a job AND enjoy watching my children throughout their recreational activities. Before Nubain I pretty much remained on the couch."

10 / 10

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23 Report

hides
April 10, 2008

Nubain (nalbuphine) for Pain "I felt like this drug worked better than vicodin, demerol and percocet. I received Nubain in the ER after a gall bladder attack. Immediate relief and no side effects from the worst pain I've ever experienced."

10 / 10

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25 Report

ncmedic
June 3, 2011

For Pain "I have been using nalbuphine for a year and a half now. I use it for migraines. I have a headache everyday and I take anywhere from 1 to 3 shots a day. This is the only thing that helps. My doctor tried me on everything. I have a problem with my pharmacy. When I go to get my medicine they treat me like I'm an addict and are very rude to me. It really bothers me. I am an E.M.T. and have been for 13 years now. I recently lost my job due to being on nalbuphine. We had a new woman hired in the office and she didn't like the idea of me taking shots so they let me go. My medicines never got in the way of my job. I am a good E.M.T. I have been given several awards for doing a great job."

9 / 10

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21 Report

Brandon
November 12, 2015

Nubain (nalbuphine) for Pain "I have chronic migraines and am on all types of medicine for them. Sometimes every month or so I get one that'll last a week. Yes a week. And I go to my primary doctor and he give me Nubain. It really is a wonderful drug for migraines I have been using it for three years now. It's completely non addicting. And it takes away my severe migraine in just 15 minutes . Weeks of pain gone after one shot ."

10 / 10

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15 Report

Are you taking this medicine?

Anonymous
October 16, 2008

Nubain (nalbuphine) for Pain "I have been suffering from severe pain for 8 years now from crushed nerves from a work related incident. I get immediate pain relief without the side effects like upset stomach, nausea, dizziness and headache. I think this a wonderful drug for a chronic pain suffer like me who gets no relief from the ther pain medications on the market."

10 / 10

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20 Report

Ginger...
December 28, 2009

Nubain (nalbuphine) for Pain "I was admitted to the hospital with a severe headache and stiff neck. I was given Demerol on one occasion it didn't really help, And upon my next visit for the same headache 3 and a half weeks later I was given Tordol for my pain and Zofran for nausea...It sure didn't help. So I was put into a room where I asked for some pain medication and the nurse told me I could get Nubain for my pain. I had never had it before to the best of my knowledge..But get this.. The doctor that admitted me saw in my chart that I had taken Methadone in the past..He asked me DO YOU STILL TAKE METHADONE?? I SAID YES EVERY DAY. The nurse gave me the Nubain and I had instant withdrawals. One week later I'm still sick with a headache."

1 / 10

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17 Report

Steph...
June 10, 2009

Nubain (nalbuphine) for Pain "I was in the emergency room due to crippling pain from my head through all my joints and bones. They gave me a shot of tramadol first and it didn't phase me. Then they gave me the Nubain and for once, I wasn't in pain. Most pain medicines won't work on me, but this worked wonders!"

9 / 10

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15 Report

thank...
July 12, 2008

Nubain (nalbuphine) for Pain "I received an injection cocktail of Nubain and Phenergren after suffering from a Migrane headache that had lasted for 6 days. I was in ER for 4 days before that and the injections they gave me there wore off and the pain was back. I was prescribed Fiorcet and it helped to some degree, but the headache was back when the medicine wore off. Once I received the Nubain, I've only had to take 1 Fiorcet, and this morning, for the first time in a week, I've been able to wake up with no pain."

9 / 10

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15 Report

ackack
May 30, 2011

Nubain (nalbuphine) for Pain "I recently received an injection of nalbuphine in a walk-in/non-life threatening ER for a cluster headache that had spiked to a 10 on the pain scale and it was an absolute revelation to me. With negligible side effects, it worked as well (10 to 6 on pain scale) as 4 times the typical IV injection of Dilaudid (so 4mg or about 16-24mg oral/60-80mg of oral morphine/100-150mcg of transdermal fentanyl/150-200mg of oral Demerol) without making me high or nod out. This was the first partial agonist (like buprenorphine) that actually helped severe pain. "

9 / 10

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13 Report

Anony...
Taken for 1 to 6 months
June 7, 2018

Nubain (nalbuphine) for Pain "I’ve been getting Nubain injections for my migraines for a few months now. I am having a migraine on average once a week for 2-3 days. My life has been doctors offices and bed. Of course I have been seeing my neurologist for help but there’s no magic wand to make migraines go away. When I can’t get rid of my migraines at home, I go see my doctor. She gives me Nubain 20mg and Promethazine 50mg. The stuff works great. The Nubain takes the pain away almost instantaneously. I can usually fall asleep and wake up pain free! My only complaint is the nausea I get from the Nubain. The promethazine helps with that though. Certainly not a permanent solution for my migraines I know but, it’s what I’m working with now."

8 / 10

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6 Report

funbags
Taken for 2 to 5 years
June 21, 2014

Nubain (nalbuphine) for Pain "I have been using Nubain for the last 6 years and I can honestly say, it's changed my life. I am in dire need of a knee replacement but nobody will do the procedure due to my age..I am told by orthopedic doctors to wait until I'm at least 46( I'm 44) so I have 2 more years to wait. I was a collegiate gymnast and coached for 17 years, have had 2 ACL surgeries and basically have bone on bone knee pain. I have tried everything..but this is a life changer. "

10 / 10

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9 Report

Mictiv
October 26, 2017

Nubain (nalbuphine) for Pain "I was administered Nubain in an ER for pain caused by the gallstones I had developed. It not only took away the pain but also made me feel relaxed and anxiety free after years of suffering from manic depression, bi-polar. I have been injecting Nubain since a few months now, just to be functional enough to make it to work and make the day pass by. I prefer (can never find a vein) intramuscular shots and find myself getting highly addicted to the substance. I'm scared but more importantly find it impossible to leave my room (read: rabbit hole) without injecting some every four to five hours."

8 / 10

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6 Report

Milk...
December 29, 2016

Nubain (nalbuphine) for Pain "I suffer from frequent migraines, several times/month. Every couple years I seem to get a massive headache that last day, after day, after day. My regular medication (sumatriptin) does nothing. It's then I head to the doctor or the ER and sometimes they will give me an injection of Nubain. That's all it takes. Headache goes away pretty quickly afterwards. Whew!"

10 / 10

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6 Report

Paula
Taken for less than 1 month
May 12, 2018

Nubain (nalbuphine) for Pain "My Dr has used Nubain sparingly for fibromyalgia flares that were continuous for more than a week. I tolerated it well and other than sedation I had no major side effect. I discontinued any other pain meds."

10 / 10

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5 Report

Autoi...
February 23, 2013

For Pain "I have severe joint pain (jaw, fingers, shoulders, elbows, knees) due to an autoimmune disease and Nalbuphine saved my quality of life. I took it as needed for pain almost daily for five years without any side effects and without ever having to increase the dose. Got a new insurance that wouldn't cover this medication and within six months I was on disability (vacillating between chronic pain and "opiate stupor"). I am fighting to get this approved again, so I can rejoin life and resume the career I loved."

10 / 10

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8 Report

Julie...
April 4, 2014

Nubain (nalbuphine) for Pain "I was administered Nubain during my labor. It made me feel extremely drunk and out of control. I remember feeling intense pain, but not really caring. The whole experience is hazy to me, which is really depressing as I looked forward to giving birth. Also, after being administered the Nubain, my labor became precipitous (I went from 3cm to 10cm in under 2 hours - not sure if this is related to the Nubain though) I would rather go drug-free than to use this again for the birth of my next baby."

2 / 10

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7 Report

lady
Taken for 5 to 10 years
March 2, 2016

Nubain (nalbuphine) for Pain "I have been having very frequent migraines that were not relieved by anything else. This medicine has been a lifesaver for me. Yes the shots hurt but it is well worth the effects of not having debilitating headaches."

10 / 10

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6 Report

Apryl
October 4, 2009

Nubain (nalbuphine) for Pain "I was laboring with Pitocin, and I couldn't get an epidural, I had a shot of Nubain in my IV and only worked for 2 minutes (literally) and I was back to feeling the full brunt of my off the chart contractions, in fact they seemed worse. For my next baby I will just labor naturally and not even try the Nubain."

1 / 10

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8 Report

Macy...
Taken for 10 years or more
June 14, 2018

For Pain "I have suffered from pain since an automobile accident in 1997 and another in 2005 ,leaving me a chronic pain management patient. I tried many opioid cocktails, but they either left me so stoned I couldn't function or didn't work at all. Most of them I found out the hard way that I was allergic to. I was finally set up with a pain management doctor and he prescribed me Nubain\Nalbuphine 20mg, it took the pain away in my neck and back immediately. Only side affect I experienced was a bit of nausea. I have been on this same med for several years now. I would never use anything else again. However it does not work for toothaches."

9 / 10

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3 Report

lilli...
August 30, 2009

Nubain (nalbuphine) for Pain "27 hours after my water broke and being induced for labor the doctor added Nubain to my IV. It was certainly effective in the way that it completely knocked me out. All I remember was getting dizzy, seeing stars and then blacking out. It was a very uncomfortable feeling almost like my consciousness was gone. When I woke up I had no feeling for how much time had passed whether the baby was already born by c-section or not. The drug certainly did kill the labor pain but for me it was too powerful with too many side effects."

2 / 10

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5 Report

MDB
Taken for 6 months to 1 year
August 28, 2018

For Pain "I suffered a pretty severe TBI from a rocket blast in Iraq. Ever since, I suffered really debilitating migraines. I mean we are talking 3+ days a week I was mostly bedridden. I had tried everything on the list for abortive measures. Came across this miracle drug and it was the first thing that actually stopped a migraine in its tracks. 20mg Nalbuphine can be paired with 12.5 to 25mg promethazine to stop both the pain and nausea. Paired this with religious visits for roughly 200 units of botox for migraine protocol and finally got my life back."

10 / 10

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2 Report

Sleep...
Taken for 2 to 5 years
May 19, 2016

For Pain "Nubain, phenergan, and zofran cocktail is typically quite effective in treating my migraines, when nothing else does. I have chronic migraine and an arsenal of weapons to combat them. When all else fails for 3+days, I head out for this cocktail injection. It makes me very sleepy but pain diminishes significantly."

7 / 10

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2 Report

DCano
Taken for less than 1 month
November 21, 2020

Nubain (nalbuphine) for Pain "I was given Nubain during childbirth. I was induced because of Preeclampsia. I went to 7 cm then ask for something for pain. That is what I was given, and then an epidural. My baby was born not breathing and I believe it was because of the Nubain. He was bagged, and rushed to the NICU. Praise God they got him breathing again, and he ending up being just fine. He had to stay in the NICU for a month. Nubain is a very bad drug. I had never heard of before they gave it to me. It was meant for AFTER CHILDBIRTH, NOT DURING. I ONLY HAD ONE DOSE. NEVER AGAIN! There is not a spot for one time use."

2 / 10

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1 Report

LCano
May 16, 2018

Nubain (nalbuphine) for Pain "Oh my goodness. I was given nubain after a hysterectomy. I was screaming in my room in pain. I had my husband call my my doctor's office and I can't even remember the curse words I used to get the doctor on the phone and when he did that poor man heard things that no man should hear. Within 15 minutes the nurses came down with Percocet and 20 mg Valium. After that I was completely sane not drowsy and could function like a normal person. The nurses on that floor came in and told me that they were going to have a consultation with the doctors because their patients were reacting so poorly to this drug and not getting any relief. Shortly after that the hospital quit using Nubain this was in Texas."

1 / 10

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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.