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User Reviews for Tapentadol

Also known as: Nucynta, Nucynta ER

Condition Avg. Rating Reviews Compare
Pain  
6.3
397 reviews 1123 medications
Diabetic Peripheral Neuropathy  
8.2
9 reviews 42 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Tapentadol

GreatLakesNY · Taken for 5 to 10 years June 9, 2021

Nucynta ER (tapentadol) for Pain: “In 31 years of chronic pain and several spine surgeries this, (100 mg 4x / day, later backed down to 75mg, with 30mg of morphine ER 2x/day. A couple months ago they took it away. Now it’s me and the small amount of diazepam and weed. I had to bring it with me when I went in for surgeries. The hospitals didn’t have it. I was lucky to get it when I did. I gather they raised the price. GREat pain reliever!!! But damn expensive.”

10 / 10
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Fifi · Taken for less than 1 month May 13, 2021

Nucynta (tapentadol) for Pain: “. For pain relief I give it ZERO stars out of 10.””

1 / 10
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Anonymous · Taken for 1 to 6 months February 17, 2021

Nucynta (tapentadol) for Pain: “Unfortunately I wasn’t able to take pain meds; however, my doctor prescribed me Nucynta and it has been a life saver. Problem is, I’m in my 40’s & have been disabled over 10 years. Most pain meds make me nauseated or cause migraines, all in all intolerable. Finally one that helps. (I have several complicated medical conditions/diagnosis’s..constantly being told I am “rare”). With Med part D, it’s $357.07. How am I supposed to live, pay the $1200 in scripts, $146 or whatever Medicare is, $55.99 for supplemental $27 for drug prescription and a $2600 deductible? Was told I make approx $70 too much per mo for assistance.”

10 / 10
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Gerry October 17, 2019

Nucynta (tapentadol) for Pain: “I have been on Nucynta 200 ERmg 3 X Day and Tramadol 50mg 3 X Day for two years now. I was on all the other pain meds from Percocet to fentanyl and Nucynta has been great for me. I have degenerative disc disease I broke my back at L4 and L5 and I have rods and screws I have a chronic case of kidney stone and kidney damage. If you have chronic pain and nothing is helping try Nucynta hopefully it might help you as it has helped me. One note, no pain medication will relieve your pain 100% but as for me my pain is 70% to 85% controlled (depending on the weather) but I have learned to live and manage my remaining pain. Apart from the medication I use ice and heat to also help with the pain. Good luck finding your pain relief because no one should live their life in chronic pain and also good luck in finding a good pain management doctor that believes you. God Bless”

9 / 10
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Cel · Taken for 2 to 5 years February 6, 2020

Nucynta (tapentadol) for Pain: “I have been on Nucynta for over 3 years now. I suffer from scoliosis, fibromyalgia and RA. I’ve been on 100 mg 4x/day then went to 3x/day recently. Something interesting about this drug is the way it’s processed in the body. Some people lack particular gene functions that break down most pain medications. Nucynta is one of the only narcotics that bypasses this gene process, therefore people who lack the cyp-2d6 (gene) “regulator”, can get more adequate pain relief. But people not lacking this genetic predisposition often have not so good of an experience. OVERALL, for some people Nucynta (tapentadol) can be a life saver when nothing else works and I say all this for those who may want to research into why certain drugs don’t work as well for them. The only downside for me was, even though I have good insurance, it was originally over $1,200 For 90- 100mg pills. Hope this helps someone!”

10 / 10
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Kinks · Taken for 5 to 10 years November 21, 2019

Nucynta (tapentadol) for Pain: “I have been on Nucynta for over 6 years. I am a post cancer patient. I suffer from nerve damage from chemotherapy, fibromyalgia. Degenerative disc disease in my lower back. Dysplasia and arthritis in my left hip after 5 surgeries and bad scarring. I have had injections and tried every opioid under the sun. Until my rheumatologist started me on Nucynta life became different. I still have pain as with ANY of them . But I got my life back. There is no generic and it is expensive but taken properly it works. It may night work for everyone. But to me roxy's and oxycodone and all that are trash. The other part is I can't have anything with acetaminophen due to having cancer in my liver .so I'm very limited. I think it's worth a try. Methadone ugh no way. People never get off that. Try nucynta! Good luck! Best!”

10 / 10
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Jp November 7, 2019

Nucynta (tapentadol) for Pain: “I have ankylosis spondylitis since I was drafted and resulted in a 4F deferment. That was 1970. This med has been a game changer for me. I wake up not as stiff as I have been without the drug. To help with the bowel motion I drink smooth moves tea and it works. If not for My Dr. I would be homeless being unable to work. Good luck to all who suffer day by day”

9 / 10
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Rose · Taken for 2 to 5 years August 24, 2019

Nucynta (tapentadol) for Pain: “I have about 8 separate diagnoses in my spine including severe degenerative disc disease and arthritis. I am in horrific pain all the time. I had been taking Vicodin 10 multiple times through the day and only got a short time of relief. I went to a new pain management doc and he gave me Nucynta. I haven't had anything work so well! I take 100mg 3 times a day and I have zero pain. I feel like a whole new person! I'm not counting the hours til I can take another pill. My co pay is 50 dollars with good insurance but for me its well , well worth it. Definitely worth giving this medicine a try.”

10 / 10
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Shano December 18, 2019

Nucynta (tapentadol) for Pain: “I broke both of my feet falling off my roof in winter after fixing my satellite I than got compartment syndrome in left foot and had to have. An emergency fasciatomy for those that don't know what that is they basically had to cut my foot wide open in 3 places to relieve the pressure and cuts had to stay wide open so for about 3 months I was in horrible pain they prescribed oxycontin 60mg 2x a day and 30mg 3x a day and for pain it did absolutely nothing but in 3 months I was addicted I went to pain management dr complained he gave me nuycenta and life was such much better went from being in excruciating pain to barely any pain at all not to mention wasn't high off pills either so could actually function.. Nuycenta was a gods send when I needed it most, the only bad thing is most insurances didn't pay for it when I was on it that was in 2015 so this might b different now but I had to pay 400 a month for 60 50 mg pills”

10 / 10
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Starr317 · Taken for 5 to 10 years February 28, 2019

Nucynta (tapentadol) for Pain: “I was in a MVA in 05 that left me permanently disabled with a spinal cord injury. My spinal cord was less than 2cm of being severed. Nothing helped the pain, not Fentanyl or even Morphine as my doctor suggested Methadone as a last resort, I was 37 yo and said no, not at my age. A PA offered Nucynta as she had just read an article and on this day, I got my life back! This wasn't just a game changer, it was a miracle drug, as it worked miracles for me. How does one thank the makers of this one med that did so much to help me and my family?”

10 / 10
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MajorDee July 29, 2019

Nucynta (tapentadol) for Pain: “I said I would come back and share. Nucynta has literally given me my life back. I have significant chronic pain issues. I was on oxycodone for a while but felt it was no longer working. Tried a few others until this one and I have felt like my pain has been relieved significantly and I am so thankful! Even my husband noticed the difference he said it was literally like night and day. So much to the point where this medication is 4 times more expensive then the others but he said with those results its worth it.”

10 / 10
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Dani4 · Taken for 1 to 6 months March 26, 2018

Nucynta ER (tapentadol) for Pain: “I have been on pain meds for 8 years due to multiple problems, as well as 2 auto immune diseases. I swear some of y’all gotta be paid reps for this drug-Nucynta-cause your so-called “experiences” of amazingness is the exact complete opposite of what I have endured while on this BOGUS medicine. Either that, or y’all had been on Aleve or Motrin for pain, and your doc prescribed the Nucynta and it’s now a wonder drug for you “compared to an OTC pain med.” cause this junk is just that-a placebo that does NOT help anyone with legit pain, who also has a “tolerance” to narcotic pain meds. There is absolutely no possible way this med is helping anyone except the pharmacy reps, doctors, and Big Pharma companies that are actually pushing this rubbish on legit pain patients. Y’all have lost your minds. You’ve been warned. It’s horrible. For pain relief I give it ZERO stars out of 5.”

1 / 10
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bamachic August 4, 2010

Nucynta (tapentadol) for Pain: “After chronic pain for 5 years (bursitis and fibromyalgia), I think I've found a medicine perfect for me. I take 50 mg three times a day; it has helped so much with the fibromyalgia fatigue/fog. I have more energy, feel less depressed, and actually wake up without horrible pain. In the past I have been on Oxycontin, MS-Contin, Hydrocodone, Fentanyl patches, and Dilaudid. Nucynta is helping more than all of the above and it's much different than a typical narcotic. I am pleased!”

8 / 10
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Yanni999 June 18, 2016

Nucynta ER (tapentadol) for Pain: “I suffered a compression fracture at L2, and I have had a failed posterior lumbar interbody fusion at L4 five and L5 S one. I am disabled and only want a life that is worth living. My New pain management physician started me early this week on Nucynta ER 100 mg every 12 hours, and for break through pain to take oxycodone acetaminophen 10/325 four times daily. I'm not getting much relief from the Nucynta ER 100 mg. I am very disappointed. I will consult with my doctor to see what he feels I should do. I am so unhappy with our government, that is harassing people that are 10 times more educated than they are, on "proper prescribing behavior" for the treatment of chronic pain. This is a disgrace to the USA!”

3 / 10
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Ritz September 24, 2019

Nucynta (tapentadol) for Pain: “I don't want to give this medication a high rating. My husband was put on this medication last week at first he thought it was great that then trouble came he had problems focusing, he broke out with a rash, had constipation could not eat and always felt like he was going to throw up. When I saw the rash on his leg I immediately call the pharmacist and a pharmacist told him to stop taking this medication and on top of that he is on antidepressants and blood thinners. ”

1 / 10
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N LW January 28, 2010

Nucynta (tapentadol) for Pain: “Nucynta did not relieve my pain at all. I have seen many negative comments about this new medicine. Many government officials want to do away with oxycodones and force people with chronic pain to get physical therapy. It's unfortunate to punish those who don't abuse their medicines.”

1 / 10
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johnnie · Taken for 5 to 10 years February 15, 2021

Nucynta (tapentadol) for Pain: “I was on 600mg of Nucynta a day for 6 fractures in thoracic spine. This worked wonderful until new opioid restrictions dropped me to 150mg a day. Now I am in constant pain. What do I do? How do I find a dr. to put me back on enough to relieve my pain”

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Laura Anderson February 13, 2020

Nucynta (tapentadol) for Pain: “I've never had more side effects with any other medication. I ended up in the ER, I'll get into that more later. -Blurry vision, can't read off my phone. Can't focus eyes, they feel strained. Causes this 'psychedelic effect' where things look like it's moving with slight colors. -Chest pain. Went to ER. Gave medication to slow heart which was 150 bpm -Heart pounding, tightness in chest, fast heart rate, low blood pressure. -unable to concentrate/poor memory. Forgetting mid sentence. -Dizzy, room is spinning. Uncoordinated. -Depressed breathing -Hallucinations. Thought I saw a red bug on me but it was just my birthmark, I was hallucinating! NEVER hallucinated before. -Restlessness -Skin on hands and feet turned blue -Anxiety/depression. I have slight anxiety but not like this. Made me depressed. -Urinary pain (from coating on these pills made to prevent people from misusing) -Heaviness in limbs -Trouble swallowing -severe constipation -Indigestion -Low energy”

1 / 10
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PolarFBear October 12, 2009

Nucynta (tapentadol) for Pain: “It seemed okay. I was more alert than when using oxycodone. After three weeks, the side effects outweigh the positives. It was more psychotic than I had planned. After the 75 mg dose wore off, the drop off was steep. I felt very agitated and somewhat aggressive. Similar to prescribed amphetamine or steroid. It makes me so agitated that I have decided to go back to the Oxy. I also experienced some respiratory distress and diminished vision. Good try as an alternative but it is not for me. Kadian had similar reactions.”

4 / 10
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geo 7 January 5, 2014

Nucynta (tapentadol) for Pain: “I have numerous chronic conditions but I will speak about my pain. I have been attending the pain clinic for approximately 5 years and have tried every conceivable pain medication that I could get including a ketamine iv , nothing has worked until now. I am on 500 mg of Palexia/tapentadol/Nucynta and it works. I have nerve damage due to an undiagnosed neurological condition with symptoms copying Multiple Sclerosis. It has taken about 8 weeks for it to work but it has made a big difference. Side effects are no sleep (chronic), dizziness (goes away) and mood swings. I want to stay on it and hopefully my doctor can help with the sleep, so anyone just on it or about to go on it please give it a bit of time.”

10 / 10
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CRIMSON VOICE · Taken for 1 to 2 years March 6, 2013

Nucynta (tapentadol) for Pain: “I am 35yrs. Old and have had severe fibromyalgia, trigeminal neuralgia, migraines and chronic fatigue. I had been suffering since my early 20's. Tried everything and backed it up with research. Nothing made the pain tolerable enough. Nucynta 100mg. E. R. 2x. A day gives me 24hr. Pain control when taken with 100mg. Of tramadol. Found the doctor who prescribed it just a year ago. I was a ball of pain on my couch, could not work, actually.... I had no life. My doctor is conducting trials in using this for fibromyalgia. 97% success. I had forgotten what a body not riddled with chronic pain felt like. He is a pioneer and trying to get this medication to those who need it to function. It was difficult to get approved. I have a life!”

9 / 10
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Lucinda Marie · Taken for less than 1 month June 27, 2014

Nucynta (tapentadol) for Pain: “I was just given Nucynta 50 mg twice a day for Peripheral Neuropathy following a botched surgical procedure by my PCP. The pain was constant and burning. It disrupted my life and is wrecking my relationship with my husband. He doesn't understand the pain of Neuropathy, Neuritis and Neuralgia. I have been in pain for more than a year and I have tried many different pain medications such as Vicodin, Ultram, Percocet. Nothing worked! I have only taken 2 pills and I noticed that the pain is much improved. It went from a 7 to a 4. That is HUGE! I did get nauseated and my breathing was shallow. I also stumble a bit and I am not able to verbalize complete sentences. That is disturbing, but it's worth it if I can experience less pain.”

7 / 10
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EDS199 · Taken for 2 to 5 years February 10, 2019

Nucynta (tapentadol) for Pain: “I am a young uni student that has been experiencing severe chronic pain for 5 years. 2 years ago my doc prescribed nucynta and it was a game changer. Before I was taking 4 different types of meds for my EDS and spinal stenosis but with no affect. Nucynta has allowed me to live with a tolerable amount of pain all while performing in university.”

10 / 10
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Skuzy June 16, 2015

Nucynta ER (tapentadol) for Pain: “I fell off of a ladder at work and shattered my elbow and slicing my nerves. After 3 surgeries over a year period I was still in a lot of pain. After going through the norco dependence I was finally referred to a pain mgmt doc who first tried Opana to no avail. I was then put on an extended release Fentanyl patch which worked but did not last near long enough between doses. The doc then put me on Nucynta ER tritated up to 250mg x2/day and it has been a godsend. I keeps my pain at bay and doesn't get me high. I will say that it seems to only last 8-10 hours but I have norco to fill the gap. Very happy with Nucynta and I feel like I have my life back. Friends and family say that I am much better to be around as well. Good luck to you!”

10 / 10
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Runner2Yogini March 5, 2013

Nucynta ER (tapentadol) for Pain: “I am 30 years old and was diagnosed with fibromyalgia when I was 25. Over the years, it kept getting worse and worse. It was beginning to interfere with my life. I had a very poor quality of life. I finally after suffering for over a year, I decided I needed real help. I had been on many other pain medications, but Nucynta ER was different. The day I got my prescription filled, and took it that night, I woke up a changed person. I'm not sure exactly how long I'd suffered but, Nucynta ER has given me my life back. My depression and anxiety are non-existent. I feel awesome!”

10 / 10
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Bimmerland · Taken for less than 1 month December 15, 2019

Nucynta (tapentadol) for Pain: “Started nucynta 100mg every 12 hours with percocet 10/325 in between for my pain. Nucynta does nothing for pain. All it does is add another level of opioid addiction. Very expensive and does not reduce my pain level. Back to spine clinic to get lower dosage so I can cleanly get off of it. Had the same experience with levorphanol.”

1 / 10
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lucynthia March 24, 2010

Nucynta (tapentadol) for Pain: “I found I had unusual energy and didn't feel my back pain, was able to do a lot of the manual chores involved in renovations and spring cleaning that I put off (due to pain and lack of motivation). So far no effects of longing for a dose. I take only when the pain comes back. I'm waiting for the negative but so far ... it's great!”

10 / 10
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MajorDee June 24, 2019

Nucynta (tapentadol) for Pain: “I am on a trial of Nucynta medication 50mg every 6 hours. I have been on several different pain medications and lately they have not been working due to a worsening condition. I have fibromyalgia, DDD (degenerative disc disease) and arthritis in my cervical and lumbar spine as well as a tumor that caused me to have a near total mandibulectomy which is now the main source of my pain. The first few days I felt very dizzy but surprisingly my pain level is so much better I cannot believe it! I hope this continues. The only downside is the cost. My co-pay was $53 dollars and that was for 7 days worth! If this works then I have to pay another $53 dollars!! So this works for me but the cost does not so I am not sure how this will all work out.”

8 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.