Skip to main content

Tapentadol User Reviews & Ratings (Page 4)

Brand names: Nucynta, Nucynta ER

Tapentadol has an average rating of 6.3 out of 10 from a total of 424 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Tapentadol

  • Pain...
  • November 20, 2015

Nucynta ER (tapentadol) for Pain "In 2012, I was in an accident. As a result, I have had 4 surgeries to my right wrist. I then developed bilateral epicondylitis, trigger finger, and myofascial pain syndrome. I have taken a variety of meds without relief. I wasn't able to participate in life or carry out routine tasks. My pain specialist prescribed Nucynta ER 50 mg, 1 tab twice a day (morning & evening). I was also prescribed Nucynta IR 50 mg, 1-2 tabs up to 4 times per day. The Nucynta ER lowers my pain throughout the day. If I have housework, etc., I can take 1 to 2 Nucynta IR prior to starting the tasks. This gives me the extra relief I need to complete the work. If my pain spikes, I can also take the IR. Nucynta has given me my life back."

8 / 10
Was this helpful?YesNo
58 Report
  • chanel
  • Taken for less than 1 month
  • April 10, 2013

Nucynta (tapentadol) for Pain "I tried this medicine at 50 mg up to 4 times per day and it is very helpful for chronic neck and shoulder pain I have suffered for years. There are no highs and lows like other pain medicines. I also had a nerve block injection to the area and that removed the pain 100%. I highly recommend it and a nerve block. It scared me too, but it worked."

9 / 10
Was this helpful?YesNo
70 Report
  • A Dude
  • Taken for 2 to 5 years
  • January 25, 2013

Nucynta (tapentadol) for Pain "I have been on Nucynta for 2 years following a ten to twelve foot fall. Nucynta is without a doubt the best pain medication I have ever been prescribed. It works well on my severe shoulder, back, and neck pain. Without the nasty side effects of other opiates I was taking, such as Hydrocodone. I am able to stay alert and I have not built up a tolerance to it. Nucynta has been a game changer for me."

10 / 10
Was this helpful?YesNo
71 Report
  • Faith...
  • August 20, 2016

Nucynta ER (tapentadol) for Pain "I have OA in my knees and muscular joint pain. I took Oxycodone for several years. I have a T11/12 herniation and two lumbar bulges. The spinal issues cause my feet to burn after lying in bed for a couple of hours, which led to many sleepless nights. I was prescribed Gabapentin. It was 90% efficient in blocking the neuropathy but caused horrible cognitive side effects. I asked the doctor to let me try Nucynta. Not only did it work better than the oxy on my OA and such, it was nearly as effective as the Gabapentin for nerve pain. I take Nucynta ER 50 twice daily and Nucynta IR 50 once daily if needed. The Nucynta causes no euphoria as with the Oxycodone. I sleep eight hours a night and have no burning sensation in my feet."

9 / 10
Was this helpful?YesNo
54 Report
  • kitty...
  • Taken for less than 1 month
  • March 10, 2019

Nucynta (tapentadol) for Pain "I was given this medication 2 weeks ago, 50 mg 3 times a day. On week 1, I felt significant relief from pain, but in the second week, 7 days later, I became stomach sick, vomiting and diarrhea, nauseous, and my back pain (3 fractured lumbar) came back with a vengeance, feeling the worst pain ever, and I'm still taking the prescribed dose. What's up with that??? I'm so disappointed because I thought, after 8 years of suffering from chronic pain day after day, that I finally found something to address this pain. But no, it lasted all of 3-4 days and now I'm feeling more pain and less relief from the same drug... back again to see the doctor."

3 / 10
Was this helpful?YesNo
40 Report

Are you taking this medicine?

  • Born
  • March 22, 2015

Nucynta (tapentadol) for Pain "Awesome drug with no narcotic hangover. With radiation damage to all the organs that I still have, the pain never goes away. Nucynta (600 mg/day) has allowed me to have a tolerable life and work much better. Best medicine since Vioxx (which was removed from the market). My pain level is down to a 6 or 7 now. Very pleased. Much better than traditional opioids that cause highness, mental, and go problems. Clear-headed on this med."

9 / 10
Was this helpful?YesNo
60 Report
  • Holyc...
  • July 26, 2013

Nucynta (tapentadol) for Pain "I started Nucynta the first time and was on a low dose of 25 mg of Zoloft. I had been taking hydrocodone 10 mg for several years. The reason for Zoloft was for minor depression that the hydrocodone causes. The first two pills I had of Nucynta caused insomnia, weird dreams, and a bit of anxiety. Also, I had shivering and felt so hot I thought I was burning up. Even though my rheumatologist/pain specialist suggested I give it 5 days, I did not. Well, a couple of weeks later, I am trying it again. So far, so good. My pain level is better but not yet all gone. I did have to take hydrocodone early in the morning as I started having withdrawal symptoms from not taking it. I was told I would not. I'm glad for Nucynta. I have neuropathy, fibromyalgia, and two kinds of arthritis."

8 / 10
Was this helpful?YesNo
67 Report
  • Ghett...
  • Taken for 1 to 6 months
  • May 1, 2016

Nucynta (tapentadol) for Pain "I'm not sure why this medication is considered a Schedule II 'narcotic.' Perhaps having been prescribed Oxycodone, Hydromorphone, and Fentanyl in the past is a factor in forming this opinion, but I have been fortunate enough to find a specialist willing to treat fibromyalgia-related pain with Nucynta. This medication does not give me any of the usual negative opioid side effects, nor the weird SSRI/SNRI type mental side effects of Tramadol. Nausea is rare and possibly unrelated, no itching, or lack of mental clarity. I can see why it would be inadequate for post-surgical or trauma-induced pain, but it works perfectly for my current state of managing physical therapy after a long period of inactivity."

10 / 10
Was this helpful?YesNo
54 Report
  • 51and...
  • July 1, 2017

Nucynta (tapentadol) for Pain "Serotonin syndrome!!! I take an antidepressant, Cymbalta 60 mg, Trazodone 50 mg, gabapentin up to 900 mg because I have CRPS and literally cannot walk due to a surfing accident that almost paralyzed me 10 years ago. DO NOT TAKE THIS MED IF YOU'RE ON any kind of antidepressant!!! It will cause you to start shaking, your heart pounds, you're dizzy, sick, and you could actually die from this! This med does nothing for my pain! If you do take it with an antidepressant, make sure you have a Narcan kit!! God bless us who depend on these doctors!!"

1 / 10
Was this helpful?YesNo
48 Report
  • ROBERT...
  • Taken for less than 1 month
  • February 27, 2016

Nucynta (tapentadol) for Pain "Pain doc just switched me to Nucynta ER 150 mg - twice daily... after making the rounds of other meds. I was on 4 mg Dilaudid before this - morphine, oxycodone - all losing some of their effect after a while; but they ALL worked better than this tapentadol stuff. I am a cancer survivor with a host of other conditions - arthritis, carpal tunnel, cervical neuropathy, and lower back pain. Not only is it having no effect on the pain - I can't sleep - have a pounding headache and now can't urinate at all (enlarged prostate). Don't like this med at all..."

1 / 10
Was this helpful?YesNo
54 Report
  • Chris...
  • August 23, 2016

Nucynta (tapentadol) for Pain "I've been on Nucynta 150 mg for months. I feel no relief of my pain, which is severe in my back. This drug doesn't even make me sleepy, it's as if I'm taking nothing! I feel it is worthless as a form of pain management!"

1 / 10
Was this helpful?YesNo
52 Report
  • Vee
  • Taken for less than 1 month
  • July 20, 2016

Nucynta (tapentadol) for Pain "For fibromyalgia - This drug did absolutely nothing for me, like taking a placebo pill. No pain relief WHATSOEVER. I was tried on 200 mg ER. I noticed that after about an hour and a half after taking a dose, I would pass out asleep for about an hour and then wake up not remembering that I even fell asleep. Very strange. I'd wake up in full-blown pain, and I also had stomach cramps, which made my pain levels and overall experience much worse. I was so hopeful for this drug because it's said to treat diabetic neuropathy, which I also have in addition to the fibromyalgia, but it didn't do anything at all to relieve my pain. You'd be better off taking Tylenol instead of this, that's how terrible it is."

1 / 10
Was this helpful?YesNo
52 Report
  • Jayce
  • October 10, 2013

Nucynta (tapentadol) for Pain "I started Nucynta 100 mg 3 times a day because I have severe back problems. Norco and Vicodin were not working. The first day I was on it, it took about an hour to kick in (around 12 AM, I got my prescription at 11 PM). I had bizarre and violent dreams. I took it before work (I didn't drive) and I have a desk job. I spent most of the day drooling. On day 2, I had a great night's sleep, with no bizarre dreams, and fell asleep without any problem. I went to work and was hot and sweaty (the office was at 69 degrees and it was raining), with the worst dry mouth you could imagine. I had no appetite and drank a ton of water. On day 3, I experienced diarrhea, sweating, and no appetite. As for pain management, it worked better than Vicodin, but I still feel a burning sensation."

5 / 10
Was this helpful?YesNo
64 Report
  • Jamelt
  • August 8, 2015

Nucynta ER (tapentadol) for Pain "Take it for back pain as needed. 100 mg dose. It works, but it makes you tired. No pain. Some days I can't even get up because of my back pain. Only problem is when I don't take it (I try not to use pain meds too much) I get really sick. Maybe it's withdrawal. That part isn't fun. But after 3 days or so of not taking it, I'm back to normal."

10 / 10
Was this helpful?YesNo
55 Report
  • Mystery...
  • Taken for 1 to 6 months
  • December 1, 2015

Nucynta (tapentadol) for Pain "I had shoulder surgery back in July 2015. I was prescribed 50 mg every 6 hours for pain. I took it just a couple of days because I did not need much of it, and the side effect, dry mouth, drove me insane. Fast forward to November 2015. I'm still experiencing severe pain in my shoulder, 9/10. So I started using these sparingly whenever I feel like I want to be pain-free. It works great, and the dry mouth is worth the pain-free time I get."

9 / 10
Was this helpful?YesNo
53 Report
  • axial...
  • Taken for less than 1 month
  • March 8, 2013

Nucynta (tapentadol) for Pain "The first 4 days were great, no pain and no lethargy. Day 5 began with stomach upset and hot flashes. Day 6 brought anxiety ending in severe depression and a psychotic break. All resolved after cessation in 24 hours."

1 / 10
Was this helpful?YesNo
65 Report
  • Himalay
  • March 2, 2014

Nucynta (tapentadol) for Pain "I was given a single dose of Nucynta for pain after hip replacement surgery. The side effects were just weird, a feeling of being disconnected from my body and mental confusion. I was also nauseous with vomiting. I never had this effect with Demerol, Percocet, or Valium. Maybe I was allergic to it."

1 / 10
Was this helpful?YesNo
61 Report
  • PitBu...
  • Taken for 2 to 5 years
  • January 26, 2016

Nucynta (tapentadol) for Pain "I have been in constant pain for 17 years (since I was 12) RSD, chronic migraine, fibromyalgia, myofascial pain syndrome, Sjögren's, and several other things. Tried everything to manage the pain and gain some of my life back. The only thing I found that helps is Nucynta. I have been on it for about 4 years, (1) 100 mg tablet every 4 hours. It's a love/hate relationship. It's the only thing that helps my pain, but I hate waking up every morning going through withdrawal because I've been on it so long. I tried the ER, but it wasn't as effective. I know it's not good to be on it for so long, but I'm at a loss for any other options to try, and it really does help me be more functional than I was without it. Besides the withdrawal, I have not had side effects."

8 / 10
Was this helpful?YesNo
52 Report
  • senec...
  • Taken for less than 1 month
  • December 11, 2016

Nucynta (tapentadol) for Pain "I have severe, constant pain following 4 serious car accidents (none my fault) over 14 years. I was taking OxyContin 10 mg x5 per day, and my Dr. recommended I try Nucynta. I don't know why. It was more expensive and not available in a generic form. After three days, I felt it was less effective in controlling my pain. On the fourth day, I woke up and felt I had nothing to live for and my life had no meaning. I have depression and PTSD caused by the accidents, but these conditions are well controlled by other medications. I normally don't have these thoughts. I believed this was a side effect of the Nucynta, so I immediately stopped taking it, and those thoughts went away right after."

5 / 10
Was this helpful?YesNo
48 Report
  • Horri...
  • Taken for 1 to 6 months
  • August 1, 2016

Nucynta (tapentadol) for Pain "I was put on this medication and taken off hydromorphone. It was horrible! I was given 50 mg three times a day. I had hot flashes, restless leg syndrome, headaches, and blurred vision. The blurred vision was so bad it was making me dizzy. It also made me so weak and washed-out feeling that I could hardly make it through the day. I went back to my pain doctor to complain about this medication, and she put me back on the hydromorphone, which was working perfectly in the first place!"

1 / 10
Was this helpful?YesNo
49 Report
  • kelly...
  • Taken for 6 months to 1 year
  • August 22, 2017

Nucynta (tapentadol) for Pain "This drug has been a game changer for me. Previously, I was maxed out on Norco 10/325 (6 a day), and it barely touched my pain (herniated disk blew out, compressed my sciatic nerve, had emergency surgery to correct that because I'd lost function in my right leg and foot; foot works now, but left with chronic severe pain), and my ability to work or even to do regular housework was severely impacted. Nucynta to the rescue! I started on 4x50mg/day, which was increased to 6 per day. After I was stable on that, I was switched to 2x100mg Nucynta ER per day, with 2x50mg Nucynta immediate release for breakthrough pain. The first couple of days, I was nauseated and a bit spacey, but soon those issues went away along with most of my pain. I love it!"

10 / 10
Was this helpful?YesNo
44 Report
  • Jo 7027
  • Taken for 1 to 2 years
  • February 12, 2015

Nucynta ER (tapentadol) for Diabetic Peripheral Neuropathy "I have tried several medications and was either allergic to them, they didn't work, or I did not like the way I felt. Nucynta has worked wonderfully with the severe neuropathy pain that I have on a daily basis. Prior to Nucynta, I had a difficult time just walking to another room, much less a grocery store. I have found that Nucynta has cut my downtime due to pain at least 50%! I do not feel dopey or high, it does not inhibit or interfere with my speech, thought, or action. In fact, I told my husband I am ready to start going bike riding again because I feel safe enough to do so and the pain is not stopping me anymore. This is my experience with Nucynta: works wonders!"

10 / 10
Was this helpful?YesNo
54 Report
  • Lumiere
  • February 16, 2014

Nucynta (tapentadol) for Pain "I was only on Nucynta for 2 days. 50 mg tabs x 3 times a day. I have been taking tramadol with no problems, but thought this might work better, as tramadol does not always control my pain. I must be very sensitive, as this medicine on day 1 made me feel as if my body were speeding, but tired and loopy at the same time. Day 2 was more of the same, but I needed a higher dose in order to control a pain level of 7 that comes upon me as the day wears on. I decided I did not want to go to 100 mg because of my sensitivity to this medicine."

5 / 10
Was this helpful?YesNo
58 Report
  • Tish...
  • Taken for 1 to 6 months
  • April 29, 2012

Nucynta ER (tapentadol) for Pain "I have fibromyalgia and severe neuropathy in both feet with burning pain all the way up to my knees. My local pain clinic prescribed Nucynta (for short-term pain), and it completely took my pain away. I did get extremely lightheaded and a feeling like I was high. Since it isn't safe for your liver for long-term use, they switched me to Nucynta ER 100 mg to start. It took 2 weeks to fully kick in, and after a month, I formed a tolerance to it. I've been on 200 mg for about 5 weeks now, and I've already built a tolerance to it as well. This prescription has been a godsend, but I can only go up to 250 mg twice per day. What will happen to me if I build a tolerance to that? I'm very concerned."

10 / 10
Was this helpful?YesNo
65 Report
  • Uncle...
  • December 20, 2013

Nucynta (tapentadol) for Pain "I tried Nucynta but had too many side effects on it. First of all, I had terrible nightmares on it, and secondly, it made me terribly constipated. I could not poop at all on Nucynta and didn't poop until 3 days after stopping taking the medication."

6 / 10
Was this helpful?YesNo
58 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.