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Tapentadol User Reviews & Ratings (Page 3)

Brand names: Nucynta, Nucynta ER

Tapentadol has an average rating of 6.4 out of 10 from a total of 436 reviews on Drugs.com. 54% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Tapentadol

Commonly mentioned side effects
  • Cin...
  • February 11, 2013

For Pain "I have been on Nucynta for 1 1/2 years. I've had major problems with pain meds. Vomiting, not sleeping, to very high liver counts. I've had 4 surgeries on my wrist in 3 years. One being an internal amputation of the ulna hump & approximately 3 feet of bone. Picture that hump in your wrist & 3 feet of the bone that is attached to it gone. Bone hitting bone, pain I wouldn't wish on anyone. My pain management doctor put me on 50mg x 2-4 times a day. For the first time in 14 years, I'm almost pain-free. I'm going this week to have the dosage increased. I had to stop working and I never thought that I would have a normal life or be able to hold my grandkids. Now I have 6 grandkids and I spend every day with them. I can even pick them up and hold them. My newest is 8 weeks old. Nucynta saved me."

9 / 10
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  • gra...
  • Taken for 6 months to 1 year
  • October 10, 2014

For Pain "I could not deal with the side effects of OxyContin or hydrocodone. Too much dizziness and severe itching. Unable to get restful sleep. Nucynta ER 50, 2 times a day has been MUCH better for me. Very little side effects and only for the first couple of weeks. I sleep better too. Only objection is that it wears off after only about 5 hours. So I have to take hydrocodone occasionally."

8 / 10
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71 Report
  • Pad...
  • October 24, 2013

For Pain "My pain management doctor switched me from Demerol to Nucynta for breakthrough pain of chronic migraines. Surprisingly, I found it to be effective, but I noticed from the start that it greatly diminished my language skills: reading, writing, and speaking. As per doctor's orders, I stayed in bed while under the effects of Nucynta, so this weird side effect didn't cause me any issues. Until... After using it for 15 months, I found my language skills to be extremely loopy, creating comments from friends and neighbors, DAYS after taking Nucynta. That scared me, and my doctor immediately took me off this medicine when I finally advised her of the language problem it presented. I could be reading a sentence and forget a word's meaning."

9 / 10
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77 Report

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  • Pt ...
  • June 11, 2014

For Pain "Tapentadol 50mg four times a day when required for pain. Before Nucynta, I was taking Opana IR as well as extended-release formula, usually alternating the two every couple of months. Pain relief is controlled best by Opana for me personally. However, several side effects have required a change, so Nucynta was chosen. Works great, no freaky side effects, and less intoxicating effects."

7 / 10
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72 Report
  • Bim...
  • Taken for less than 1 month
  • December 15, 2019

For Pain "Started Nucynta 100 mg every 12 hours with Percocet 10/325 in between for my pain. Nucynta does nothing for pain. All it does is add another level of opioid addiction. Very expensive and does not reduce my pain level. Back to spine clinic to get a lower dosage so I can cleanly get off of it. Had the same experience with levorphanol."

1 / 10
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45 Report

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  • Coc...
  • September 7, 2015

For Pain "I have a cyst along my spine with a messed-up disc. The codeine-based medicine's side effects were terrible. Nucynta 75 mg, 3 times a day, works wonders. I only take it when I do a lot of work, which affects my lower back. My wife likes me to take it as I am not as grumpy. Like all medicines, some work for certain people and not for others. For me, Nucynta and Demerol work best with minimal side effects."

9 / 10
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  • Bec...
  • Taken for 1 to 2 years
  • February 3, 2019

For Pain "This medicine has been such a blessing for me. Felt as if my quality of life was completely lost from chronic pain. Multiple spinal issues and three surgeries later, I was left with terrible neuropathy and pain all down my right side. This did the trick. Now I have my life back!"

10 / 10
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  • Fai...
  • August 20, 2016

For Pain "I have OA in my knees and muscular joint pain. I took Oxycodone for several years. I have a T11/12 herniation and two lumbar bulges. The spinal issues cause my feet to burn after lying in bed for a couple of hours, which led to many sleepless nights. I was prescribed Gabapentin. It was 90% efficient in blocking the neuropathy but caused horrible cognitive side effects. I asked the doctor to let me try Nucynta. Not only did it work better than the oxy on my OA and such, it was nearly as effective as the Gabapentin for nerve pain. I take Nucynta ER 50 twice daily and Nucynta IR 50 once daily if needed. The Nucynta causes no euphoria as with the Oxycodone. I sleep eight hours a night and have no burning sensation in my feet."

9 / 10
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  • Lul...
  • Taken for 1 to 6 months
  • December 13, 2016

For Pain "I have 4 slipped discs and a self-fusing spine, and I'm only 36. I have terrible OA in my spine that's hereditary. I failed epidural injections. The nerve pain kept me in bed crying most days, and I couldn't be a wife or mom. I started on Norco, then moved to Oxycodone. They added Neurontin, and nothing took care of the burning, shooting pain that was at the base of my skull and down my left arm. I got intermittent relief for one year. I changed doctors, and they put me on Nucynta ER 250 mg once a day! I can honestly say I am pain-free. I only take this and an anti-inflammatory. I will say the consistent side effect is nausea, vomiting, and no appetite. I don't mind it, as I'm finally pain-free, and I just eat small meals!"

9 / 10
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57 Report
  • d91...
  • February 26, 2016

For Pain "I got Nucynta after I had surgery on my hand. I severed tendons, and the recovery was awful. I was given Norco and then also Nucynta. The second night I took the Nucynta, I started to feel strange. My heart was racing, and I felt panicky. My boyfriend asked me if I was okay, and I couldn't answer him. I stared at him because I was trying to not have a panic attack. The feeling I felt is hard to explain. I just knew something was wrong and I was having some kind of reaction. Finally, I asked him to take me to the hospital. Once on the freeway, I had a hallucination. I saw a 20 ft tall figure on the side of the road. I swear on my life. No other drugs were involved. I don't drink and have never had this happen before. I was okay a few hours later, but it was scary!"

1 / 10
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  • hal...
  • Taken for less than 1 month
  • November 12, 2013

For Pain "I'm taking 75 mg qid for severe spinal degeneration as well as other issues. In the past, I used Dilaudid, Percocet, and MS Contin. Nucynta works great for pain, but I am more tired than with other drugs. My insurance company denied approval, so I faxed them a letter explaining why I needed it, and they approved it 10 minutes after the fax was sent. Thank God!"

9 / 10
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73 Report
  • Anonymous
  • May 6, 2012

For Pain "This is a great, stable medication. I take it twice a day and have other medication for breakthrough pain. I had 2 back surgeries and 20-30 epidurals. I'm young (less than 40). It is not cheap, but I find it worth the price. I am a lawyer and need to be quick on my feet. This medication does not weigh me down mentally."

10 / 10
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  • jga...
  • April 2, 2010

For Pain "I have only been taking Nucynta for about a week. It was prescribed to me for severe pain caused by nerve regeneration in my lumbar and sacral joints. I have been very close to being completely pain-free thanks to my doctor's willingness to try this medicine. The only drawbacks I've had were pounding headaches the first couple of days. Through God's help and the right medicines, I'm feeling much better."

8 / 10
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  • Maj...
  • June 24, 2019

For Pain "I am on a trial of Nucynta medication 50 mg every 6 hours. I have been on several different pain medications, and lately they have not been working due to a worsening condition. I have fibromyalgia, DDD (degenerative disc disease), and arthritis in my cervical and lumbar spine, as well as a tumor that caused me to have a near-total mandibulectomy, which is now the main source of my pain. The first few days I felt very dizzy, but surprisingly my pain level is so much better, I cannot believe it! I hope this continues. The only downside is the cost. My co-pay was $53, and that was for 7 days' worth! If this works, then I have to pay another $53! So this works for me, but the cost does not, so I am not sure how this will all work out."

8 / 10
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  • Ste...
  • Taken for 1 to 2 years
  • September 3, 2018

For Pain "On 50 mg three times a day for 2 years. I took it to treat Reflex Sympathetic Dystrophy, also known as Complex Regional Pain Syndrome. Tolerated well, and it seemed to help a little, just enough to take the edge off the pain. After two years, it stopped working, so the dose was increased to 75 mg three times a day, which caused the side effect of Serotonin Syndrome. I had to be hospitalized and almost died from extreme acute hypertension! Almost a year later and still suffering from the incident. It ruined my life. Be extremely careful! My doctor will not prescribe it anymore for any of his patients because of the severity of adverse side effects he has witnessed in some of his patients. And if your doctor does increase your dose or add a new drug, check for interactions in case they don't know."

2 / 10
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  • Mib...
  • May 20, 2014

For Pain "After orthopedic foot surgery, I was prescribed Percocet. After side effects, my medication was changed to Nucynta. For me, I prefer the Nucynta. My problems with constipation went away immediately. I had a little itchiness from Nucynta, but nothing I couldn't tolerate. I got much better pain relief from the Nucynta too. Good thing I have insurance as it's very pricey."

10 / 10
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  • Lad...
  • February 10, 2010

For Pain "Nucynta has worked very well for all my aches and pains, from the most severe to those I didn't even know I had. At first, it did make me groggy, which was a problem, but I kept taking it anyway because it did take away most of my pain. After a couple of months of use, it takes away my pain just like it did at the beginning, but I no longer feel sleepy. I feel energetic, happier, and am very active because I hardly feel any pain. I highly recommend it, but you do have to give it a chance because once your body adapts to it, the adverse effects far outweigh the benefits."

10 / 10
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  • Pai...
  • November 20, 2015

For Pain "In 2012, I was in an accident. As a result, I have had 4 surgeries to my right wrist. I then developed bilateral epicondylitis, trigger finger, and myofascial pain syndrome. I have taken a variety of meds without relief. I wasn't able to participate in life or carry out routine tasks. My pain specialist prescribed Nucynta ER 50 mg, 1 tab twice a day (morning & evening). I was also prescribed Nucynta IR 50 mg, 1-2 tabs up to 4 times per day. The Nucynta ER lowers my pain throughout the day. If I have housework, etc., I can take 1 to 2 Nucynta IR prior to starting the tasks. This gives me the extra relief I need to complete the work. If my pain spikes, I can also take the IR. Nucynta has given me my life back."

8 / 10
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  • ams...
  • August 16, 2014

For Pain "I have acute sciatica and have been taking Percocet 10 mg along with tramadol 4 times a day. I was getting concerned about the acetaminophen, so I asked my doctor for Nucynta. I was prescribed 50 mg along with the tramadol, but I had gotten no pain relief. Then I started taking 100 mg, but the pain is still very noticeable. For me, the Percocet seems to do a better job of pain relief."

5 / 10
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  • Chr...
  • August 23, 2016

For Pain "I've been on Nucynta 150 mg for months. I feel no relief of my pain, which is severe in my back. This drug doesn't even make me sleepy, it's as if I'm taking nothing! I feel it is worthless as a form of pain management!"

1 / 10
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  • Spr...
  • October 17, 2013

For Pain "I have been taking Nucynta for about 2 years now. This medicine seems to be helping with my back pain. I started at the low dose of 50 mg, then went to 75 mg and am now taking 100 mg every 4-5 hours, as well as taking the 100 mg Extended Release tablets every 12 hours. They work great, although my only complaint would be that they make me sweat profusely when doing any activity that includes work. I even start to pour sweat when just sitting after 1 hour of taking it. As well, it makes me very tired. I find myself trying hard to keep my eyes open when I'm sedentary."

9 / 10
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68 Report
  • Ros...
  • March 2, 2014

For Pain "After taking the second pill, I had to go to the ER. I couldn't control my emotions, I broke down, bawling like a baby for no reason, just an uncontrollable need to cry. I never had these side effects with opiate pain relievers."

1 / 10
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72 Report
  • A D...
  • Taken for 2 to 5 years
  • January 25, 2013

For Pain "I have been on Nucynta for 2 years following a ten to twelve foot fall. Nucynta is without a doubt the best pain medication I have ever been prescribed. It works well on my severe shoulder, back, and neck pain. Without the nasty side effects of other opiates I was taking, such as Hydrocodone. I am able to stay alert and I have not built up a tolerance to it. Nucynta has been a game changer for me."

10 / 10
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  • Hol...
  • July 26, 2013

For Pain "I started Nucynta the first time and was on a low dose of 25 mg of Zoloft. I had been taking hydrocodone 10 mg for several years. The reason for Zoloft was for minor depression that the hydrocodone causes. The first two pills I had of Nucynta caused insomnia, weird dreams, and a bit of anxiety. Also, I had shivering and felt so hot I thought I was burning up. Even though my rheumatologist/pain specialist suggested I give it 5 days, I did not. Well, a couple of weeks later, I am trying it again. So far, so good. My pain level is better but not yet all gone. I did have to take hydrocodone early in the morning as I started having withdrawal symptoms from not taking it. I was told I would not. I'm glad for Nucynta. I have neuropathy, fibromyalgia, and two kinds of arthritis."

8 / 10
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67 Report
  • Bor...
  • March 22, 2015

For Pain "Awesome drug with no narcotic hangover. With radiation damage to all the organs that I still have, the pain never goes away. Nucynta (600 mg/day) has allowed me to have a tolerable life and work much better. Best medicine since Vioxx (which was removed from the market). My pain level is down to a 6 or 7 now. Very pleased. Much better than traditional opioids that cause highness, mental, and go problems. Clear-headed on this med."

9 / 10
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61 Report

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