Oxyfast

Generic name: oxycodone [ ox-i-KOE-done ]
Other brand names of oxycodone include Oxaydo, OxyCONTIN, Roxicodone, RoxyBond, Xtampza ER, Oxyfast, OxyIR
Drug class: Opioids (narcotic analgesics)

Medically reviewed by Drugs.com on Jan 23, 2024. Written by Cerner Multum.

What is Oxyfast?

Oxyfast is an opioid pain medication used to treat moderate to severe pain. This medicine is usually given after other treatments did not work or were not tolerated.

Extended-release Oxyfast is for around-the-clock treatment of severe and chronic pain that requires longer treatment. Oxyfast is not for use on an as-needed basis.

Oxyfast may also be used for purposes not listed in this medication guide.

Oxyfast side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur, especially if you drink alcohol or use other drugs that cause drowsiness or slow breathing. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Oxyfast may cause serious side effects. Call your doctor at once if you have:

• slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);

• chest pain, fast or pounding heartbeats;

• a seizure, extreme drowsiness; or

• decreased adrenal gland hormones--nausea, vomiting, stomach pain, loss of appetite, feeling tired or light-headed, muscle or joint pain, skin discoloration, craving salty foods.

Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of Oxyfast may include:

• sleep problems (insomnia), itching;

• drowsiness, headache, dizziness, tiredness; or

• constipation, stomach pain, nausea, vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.

Fatal side effects may occur if you also drink alcohol or use other drugs that cause drowsiness or slow breathing.

Using opioid medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Before taking this medicine

You should not use Oxyfast if you are allergic to it, or if you have severe asthma, breathing problems or a stomach or bowel obstruction (including paralytic ileus).

Tell your doctor if you have ever had:

• other breathing problems, sleep apnea (breathing that stops during sleep);

• a head injury, brain tumor, high pressure inside the skull, or seizures, drug or alcohol addiction, or mental illness;

• if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine;

• urination problems, problems with your gallbladder, pancreas, thyroid, or adrenal gland; or

• liver or kidney disease.

Most forms of oxycodone are not approved for use in people under 18 years old. The extended-release tablets should not be given to a child younger than 11 years old.

Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with Oxyfast could cause a serious condition called serotonin syndrome.

May harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you use Oxyfast during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Do not breastfeed. Oxyfast in breast milk can cause life-threatening side effects in a nursing baby.

Long-term Oxyfast may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using Oxyfast.

How should I take Oxyfast?

Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use Oxyfast in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.

Never share opioid medicine with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Never crush a pill or use the liquid to inhale the mixture or inject it into your vein. This could result in death.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using exactly as directed on the label, or as prescribed by your doctor.

Stop taking all other around-the-clock opioid pain medicines when you start taking extended-release Oxyfast.

Swallow the extended-release forms whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Take the extended-release capsules with food. Read and carefully follow the instructions for use on how to prepare and take this medicine if you cannot swallow extended release capsules whole or you use a feeding tube. Ask your doctor or pharmacist if you don't understand these instructions.  

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

You may be given other medications to help prevent or treat certain side effects.

You may have withdrawal symptoms if you stop using Oxyfast suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep your medicine in a place where no one can use it improperly.

Do not keep leftover medicine. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist about a drug take-back program, or flush the unused medicine down the toilet.

What happens if I miss a dose?

Since Oxyfast is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or person using opioid medicine without a prescription.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

What should I avoid while taking Oxyfast?

Do not drink alcohol or any products that contain alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Oxyfast will affect you. Dizziness or drowsiness can causing falls, accidents, or severe injuries. Also avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

What other drugs will affect Oxyfast?

You may have a fatal Oxyfast overdose if you start or stop using certain medicines. Tell your doctor about all your medications. Tell your doctor about all your medications especially if you use medicine to treat HIV, antibiotic, antifungal medication, or seizure medication.

Many other drugs can be dangerous when used with opioid medicine. Tell your doctor if you also use:

• medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder;

• other opioid medicines, a benzodiazepine sedative like Valium, Klonopin, or Xanax;

• sleep medicine, muscle relaxers, or other drugs that make you drowsy; or

• drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease.

This list is not complete and many other drugs may affect Oxyfast. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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