User Reviews for Nucala
Nucala has an average rating of 7.0 out of 10 from a total of 58 ratings on Drugs.com. 61% of those users who reviewed Nucala reported a positive effect, while 22% reported a negative effect.
|Asthma||47 reviews||146 medications|
|Eosinophilic Granulomatosis with Polyangiitis||10 reviews||1 medications|
|Asthma, Maintenance||1 reviews||124 medications|
|Summary of Nucala reviews||7.0||58 reviews|
Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.
For Asthma: “Basically has cured me haven’t taken any steroid since I’ve been using Nucala. Was using large amounts of oral steroid and have just recently gone to lower steroid inhaler”
For Asthma, Maintenance: “I have had severe asthma for most of my adult life . Despite oral and inhaled steroids my asthma was poorly controlled . Three years ago I began treatment with Nucala and my condition has improved significantly. After the first dose an improvement occurred and now my health is much better than it was 7 years ago when due to ill health I was forced to take medical retirement. This drug has worked so well for me and I'm so grateful to be given it .”
For Eosinophilic Granulomatosis with Polyangiitis: “I have had asthma on and off for 60 years. Last year a blood test showed Eosinophilic Asthma which made me eligible for Nucala. This is subsidised by the Australian Government. Over the years I no longer responded to prednisone or inhalers and was very glad that Nucala worked for the first 3 months. I felt like a new woman and my respiratory specialist was overjoyed that at last something worked. But after another 2 months I no longer had any benefit for my breathlessness. I am due for injection No. 6 next week, so I will see if I respond again favourably. I had no side effects.”
Frequently asked questions
- How long does it take for Nucala to work?
- Can Nucala cause weight gain?
- Can Nucala be self-administered?
- What is Nucala (mepolizumab) used for and how is it given?
For Asthma: “My doctor told me that it might take time to work, yet, my asthma symptoms disappeared the first day! I have suffered with asthma for thirteen years. After a few years with an inhaled cortical steroid, I developed Cushings' syndrome, so I could no longer take them. My doctors have tried to control my asthma with a combination of medications not containing steroids, including some COPD meds. Over the years, my symptoms became more severe and more frequent. For the past several years, I was bedridden about half the time. I had asthma attacks even with no common triggers. I used a nebulizer and albuterol six times a day. Since starting Nucala two months ago, I am symptom free and up from bed, living my glorious life!”
For Asthma: “After being on prednisone for years and no improvement. Nothing to lose but to try Nucala. Well it have helped tremendously. My breathing issue, stuffy nose, tons of mucus have stopped. However, After the first needle, I notice I have flu like symptoms, I thought I was having the flu. After second needle same thing, the doctor said to continue Nucala. Well while it improve my asthma, I am having severe back pain, pain all over my body. I am actually suffering in pain. Can someone please let me know if anyone else is having the same side effect, so I can prove to my doctor it is not in my head. While I like that my asthma have improve. I am suffering and cannot walk from pain everywhere in my body. Please let me know there is someone else experiencing this. Thanks”
For Asthma: “After two years on nucala, I have had enough. For the past three months, I have had excruciating joint pain in my knees, ankles, wrists, elbows and fingers to the point that I can not run at all or even walk without pain. While on nucala, my joints have always been hurting, but now it's just so much worse. I've also suffered from headaches, sore throat, muscle spasms, chest and back pain and some eczema. I lost half of my hair in the last two months and some of my eyebrows as well. Weird thing is, all was well for over a year and a half, except for some minor joint ache but then suddenly everything went bad really fast. Now I have to wait for a few months for nucala to leave my system, and hopefully things will return to normal. It did help with my asthma and nasal polyps, but now the side effects are just too much.”
For Asthma: “I am a very lucky lady. Nucala has been fantastic for me from the get go. Been taking a monthly shot for over 2 years now and I rarely use my rescue inhaler and have not had to take prednisone. Yahoo! Before Nucala, I had severe bronchitis episodes one after another. Was on heavy doses of prednisone which had begun not to help at all. Thank goodness for Nucala. I can go on walks again and be more active.”
- Can Nucala cause weight gain?
- How long does it take for Nucala to work?
- What is Nucala (mepolizumab) used for and how is it given?
- Can Nucala be self-administered?
For Eosinophilic Granulomatosis with Polyangiitis: “I've been on Nucala for two years. I have Chronic Eosinophilic Pneumonia. My treatment before Nucala was 30 to 40 mg of Predinsone. I'am down to 5 mg of Predinsone now. 10 mg on a bad day. And zero side effects. I say Amen.”
For Asthma: “I have been on Nucala for 2 years. I am 41 years old. I’ve had several sinus infections, coughing like crazy, reflux. When the Dr discovered I had Eosinophic allergic asthma, he put me on Nucala. About 10 minutes after my injection I had severe back pain & fatigue. As time goes by, I’m noticing more side effects. I’ve lost 30% of my hair. Severe dry skin on face. Arthritic pain. Headaches. Nucala has helped me tremendously, but I’m so upset about all my thinning/lost hair. I’ve had every blood test done. Thyroid checked. All good. Has to be a side effect. Everyone PLEASE REPORT ALLLLL YOUR SIDE EFFECTS!!! They need to know so many people are suffering from hair loss, joint pain, fatigue, headaches, muscle spasms, ..etc I have to meet with my Dr again to go over all this.”
For Asthma: “My doctor seems to be playing a guessing game with my asthma, but I guess that might be what everyone's pulmonary doctor does these days. I had pneumonia and a horrible cough, and woke up in middle of the night unable to breathe even after six puffs on my inhaler. Ever since that illness, five months later, I need a nebulizer treatment at least three times a day. I started this drug on May 8th, and at the end of the first month developed a severe bladder infection. I am now a week into my second month, still having bladder infection issues, and absolutely NO change in my severe asthma symptoms. The website indicates it can cause UTIs, so I fear that I have three more weeks of misery with a bladder infection AND severe asthma. I am glad this works for some people, but it has done nothing but make me more miserable than I already was before I started the drug.”
For Asthma: “I have been on Nucala for almost a year after being on Xolair (similar biologic) for 15 years. I haven't noticed any significant change since switching to Nucala; I very much like that I get the injection only once a month compared to every 2 weeks with Xolair. For me, it's an excellent drug to keep my severe asthma under control.”
For Asthma: “I suffered from severe asthma for the past 4 years. I was hospitalized several times, despite using 4 different asthma medications. Nothing seemed to control my symptoms for very long, except high doses of prednisone. After a blood test, and some pre-approval from my insurance company, my doctor finally got me approved for Nucala. Nucala has been a life changer. I can finally breathe much easier, I'm able to exercise, enjoy the outdoors & I rarely have asthma attacks now.”
For Eosinophilic Granulomatosis with Polyangiitis: “I have eosinophilic Asthma and took xolair for 10 years until it started to cause severe back pain and leg pain , I stopped the xolair and the pain went away entirely... started the nucala January 2019 and at first it worked like a charm for the asthma but I always had some type of flu like symptoms. As time went on the Nucala became less and less effective and I am still having what feels like a constant flu like virus all the time, some anxiety and constant stomach aches. The last shot I developed shingles within a day and a half after the shot. I truly believe these monoclonal antibody therapies (Xolair, Nucala, Frasenra etc) are decreasing our immune systems and creating a more immunosuppressed environment. I am not sure what I am going to do at this point but I hope I am not doing more harm than good to my body”
For Asthma: “I've had asthma since I was 18. Over the last 36 years, it has gotten progressively worse. My lungs were always congested and breathing was always labored. Prednisone used to work for a few months and clear up those symptoms but not anymore. Already in my 50s and my breathing getting steadily worse, I did some research to find the best respiratory hospital in the USA. In July 2015 which I went to and I was diagnosed with eociniphilic asthma but Nucala wasn't yet approved. I started Nucala in April 2017. By the fourth shot, I'm a new person. I can breathe without lung congestion and haven't used my rescue inhaler at all in five weeks. It's a miracle drug! Thank you GlaxoSmthKline!!”
For Asthma: “I got my first shot of a year ago. It was life changing! I can now breath for the first time in my life. I was in and out of the hospital before for exacerbations. My lungs are permanently scared and airways remodeled because of my asthma. Nucala changed my life. I had a little trouble getting it through insurance, copay program saved me! I thank God for Nucala. My only side effect is headache the day of shot. I am now doing self injector at home.”
For Asthma: “Started Nucala 8 months ago for my asthma and it started working within a week. I was surprised what a difference it made. It was like my asthma was almost gone. But the past month or so, I’ve started to wheeze again; now my cough is back and doing physical things is becoming more difficult. Is anyone else finding the effects fading, the longer your on it?”
For Asthma: “I have had 2 shots of Nucala over the past 5 weeks. It improved my asthma immediately. I estimate within a couple of hours the mucus, congestion and infection in my respiratory system had gone completely. However ... the side effects for me have possibly been even worse. Since the first injection I have had constant arthritic pain in my feet, back and jaw. I've also had the worst gout attack in my life. This pain has been nothing like I've previously experienced and it's affected my lifestyle significantly. I also have the minor flu-like symptoms. Although this is relatively mild, it's constant. I won't go away. I honestly don't know if I will be able to continue on Nucala. I'll need to make a call on that over the next 3 weeks. Has anyone else experienced anything like this?”
For Asthma: “I have been taking Nucala for 9 months. I have severe persistent Eosinophilic Asthma. My asthma had a rapid onset and began about 2 years ago. I was completely healthy prior. I was using a nebulizer every 2-3 hrs around the clock and on 02 at 3-5L because my airways were so tight. 10 days after the first injection and I was no longer requiring oxygen or neb treatments. Over the course of treatment I've had a few minor set backs but they've been small in comparison to what I was living prior. The first couple of months I had bad headaches and some back aches but both resolved with ibuprofen. I get tired and flu like at times but a short rest usually takes care of that. I have minor skin issues and my hair has thinned a bit but those are things that I'm willing to deal with to have my life back. I can take my grandbaby on walks in her stroller and not be gasping for air. Nucala has been life changing for me.”
For Asthma: “Nucala deserves 7 stars. Nucala co-pay program should be discontinued. I have had Asthma all my life. I am 46 years old. I have also been on steroids since I was 10. I had almost immediate results after my first injection. I haven’t used my rescue inhaler once, which is unheard of. However, my blood pressure has sky rocketed. The only thing I can relate that is new, is the Nucala. Also, I was approved for their co-payment program. Don’t be fooled. They claimed to cover anything Nucala related, up to $11,000 a year. Wrong. They’ve changed their process. After being approved for the program and starting it, now they want me to pay up front and they will reimburse me after its approved. It’s been hell to get reimbursed (I haven't seen a $1) and fee’s are racking up quickly. Even the doctors office doesn’t understand their billing. To save my credit rating, I will have to pay for the fee’s and discontinue Nucala. Their co-pay program is terrible!!! Don’t be fooled!”
For Asthma: “I've always had bad asthma as a kid. I was constantly had to be put on steroids. My Dr did an IgE test and mine were over 1,500 (less than 100 is normal) I was put on Nucala for 5 months. At the time of the first injection my lung function was at 86% at the time of the fifth injection I was at around 35%. While on this drug I felt so sick! Back pain, head ache, nausea, fatigue. I felt like I had the flu everyday! We decided to stop the drug. (I am still looking for a new treatment option)”
For Asthma: “I am an anesthesiologist who was forced onto disability due to my asthma 8 years ago .I have had asthma for nearly two decades. My symptoms were getting worse and all of the doctors I went to just doubled the dosage of my meds that weren't working. Yesterday I had my first injection of Nucala and I woke up today a new man. NO WHEEZING, NO COUGH, NO RUNNING NOSE, NO CHOKING WHEN I EAT, NO SHORTNESS OF BREATHE, I am a lucky guy......”
For Asthma: “I had my first Nucala shot in June 2019 and it seems to help my asthma. I completely stopped taking prednisone. Which was amazing because I have become totally depend on it to breath. My second nucala shot I started to notice several side effects, severe back pain, stomach pain, urinary track infection and the final straw was severe muscle pain and spams. The pain I experience from the muscle spams is so bad I cry. I had to discontinue this drug. I was very hopeful this would be the answer to my asthma. So now I am back prednisone.”
For Eosinophilic Granulomatosis with Polyangiitis: “I was put on nucala after finally seeing a pulmonologist, after hospital admissions by ambulance for E type asthma , I also have a rare lung disease, I am non smoker my whole life, after first injection, I had side effects come on very strong , nausea, vertigo, pain, arthritis in back feet ,ulcers in mouth, broken cracked gums ,rash on my back skin ,ear infections ,painful and to the point I couldn't drive my car due to onset of severe vertigo. I rang the Nucala company and explained my anguish, then saw my specialist, after 3 injections , I still had asthma all through treatment so was told to stop immediately. This drug challenged me ,like chemotherapy, it may work for some people, but not others. I've had chemotherapy in the past and found that Nucala reminded me of chemo treatments ,I hope they find more ways to control asthma in the future”
For Asthma: “I’ve been taking this for about three years now. I know it is an effective health option for me. As I find myself having a difficult time breathing then I look at the calendar. Yep. I’m a few days away from the next injection. I’m one of those people out there that enjoy oxygen when I breathe in, I know radical. I don’t have reactions to the medication, not after the first time and not today either. I thank God for giving someone out there the ability to figure this medicine out for me.”
For Asthma: “I just had my 4th Nucala shot.I am not impressed. My severe asthma is still horrible. The shots seem to not help me. My pulmonologist said that I needed to try it through the 4th shot. I got it this morning and had 3 bad asthma attacks since then. I am going to contact my pulmonologist as soon as possible. I am not going to get anymore Nucala shots. Everyone of the shots did absolutely for my severe asthma.”
For Asthma: “Until I started taking Nacala, my asthma was mostly out of control. Now, in combination with daily high dose cortiosteroides I feel like I have a new set of lungs and have got rid of the elephant that used to feel like it was standing on my chest”
For Eosinophilic Granulomatosis with Polyangiitis: “I have been getting the Nucala injections for about 6 months now and the first couple of months I could breath ok but developed a sinus/ear infection that caused a complete blockage to my ear. Have still been having to use my nebulizer treatments and rescue inhaler and have severe fatigue, headaches, muscle spasms and back pain. I will not be getting anymore of these injections.”
For Asthma: “I have just taken my 5th injection of Nucala on July 2nd and although my severe asthma, allergy, GERD, and Sternum and back pain is finally gone, I have had a sore throat for a month and a half and now I am experiencing extreme hair loss. I have lost nearly half my long beautiful hair in just the last three weeks. I have added no other meds and it seems each month as Nucala has built in my system, side effects have increased for me. As much as it has alleviated my eosinophilic asthma, I can’t live with out hair or with this chronic sore throat. I am going to an ENT soon to rule out any other cause as my general doctor nor allergist can find no cause for the throat discomfort. I am also going for blood work on Monday to check for other issues than can cause sudden hair loss, but I am betting I will have to go off this medication.”
This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.
More about Nucala (mepolizumab)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Pricing & Coupons
- En Español
- Drug class: interleukin inhibitors
- FDA Approval History
- Patient Information
- Nucala (Advanced Reading)
- Nucala (Mepolizumab Auto-Injectors and Prefilled Syringes)
- Nucala (Mepolizumab Vials)