Nucala and Headaches: What Users Say

• Nic...
• August 6, 2019

For Asthma "I have been on Nucala for 2 years. I am 41 years old. I’ve had several sinus infections, coughing like crazy, reflux. When the Dr. discovered I had Eosinophilic allergic asthma, he put me on Nucala. About 10 minutes after my injection, I had severe back pain & fatigue. As time goes by, I’m noticing more side effects. I’ve lost 30% of my hair. Severe dry skin on face. Arthritic pain. Headaches. Nucala has helped me tremendously, but I’m so upset about all my thinning/lost hair. I’ve had every blood test done. Thyroid checked. All good. Has to be a side effect. Everyone, PLEASE REPORT ALL YOUR SIDE EFFECTS!!! They need to know so many people are suffering from hair loss, joint pain, fatigue, headaches, muscle spasms, etc. I have to meet with my Dr. again to go over all this."

• Alw...
• Taken for 1 to 2 years
• January 24, 2020

For Asthma "After two years on Nucala, I have had enough. For the past three months, I have had excruciating joint pain in my knees, ankles, wrists, elbows, and fingers to the point that I cannot run at all or even walk without pain. While on Nucala, my joints have always been hurting, but now it's just so much worse. I've also suffered from headaches, sore throat, muscle spasms, chest and back pain, and some eczema. I lost half of my hair in the last two months and some of my eyebrows as well. The weird thing is, all was well for over a year and a half, except for some minor joint ache, but then suddenly everything went bad really fast. Now I have to wait for a few months for Nucala to leave my system, and hopefully things will return to normal. It did help with my asthma and nasal polyps, but now the side effects are just too much."

• Lex...
• March 27, 2017

For Asthma "I've always had bad asthma as a kid. I was constantly put on steroids. My doctor did an IgE test, and mine was over 1,500 (less than 100 is normal). I was put on Nucala for 5 months. At the time of the first injection, my lung function was at 86%, at the time of the fifth injection, I was at around 35%. While on this drug, I felt so sick! Back pain, headache, nausea, fatigue. I felt like I had the flu every day! We decided to stop the drug. (I am still looking for a new treatment option)"

• Ran...
• Taken for 1 to 2 years
• November 6, 2019

For Asthma "I got my first shot a year ago. It was life-changing! I can now breathe for the first time in my life. I was in and out of the hospital before for exacerbations. My lungs are permanently scarred and airways remodeled because of my asthma. Nucala changed my life. I had a little trouble getting it through insurance, the copay program saved me! I thank God for Nucala. My only side effect is headache the day of the shot. I am now doing self-injector at home."

• Pjb...
• Taken for 1 to 6 months
• February 25, 2022

For Hypereosinophilic Syndrome "Just received my 3 shots (300 milligrams) and administered it at home. After working with my doctors. My eosinophils have gone down. But the tiredness, back pain, and headaches are horrible. Time will tell if this will be worth it. Totally off prednisone after years of taking it. Unfortunately, severe osteoporosis from the prednisone. Age 57."

• Anonymous
• Taken for 1 to 6 months
• February 27, 2020

For Eosinophilic Granulomatosis with Polyangiitis "I have been getting the Nucala injections for about 6 months now, and for the first couple of months, I could breathe okay but developed a sinus/ear infection that caused a complete blockage in my ear. I have still been having to use my nebulizer treatments and rescue inhaler and have severe fatigue, headaches, muscle spasms, and back pain. I will not be getting any more of these injections."

• Anonymous
• Taken for 6 months to 1 year
• December 26, 2020

For Asthma "I have been taking Nucala for 9 months. I have severe persistent eosinophilic asthma. My asthma had a rapid onset and began about 2 years ago. I was completely healthy prior. I was using a nebulizer every 2-3 hours around the clock and on 02 at 3-5L because my airways were so tight. 10 days after the first injection, I was no longer requiring oxygen or neb treatments. Over the course of treatment, I've had a few minor setbacks, but they've been small in comparison to what I was living prior. The first couple of months, I had bad headaches and some backaches, but both resolved with ibuprofen. I get tired and flu-like at times, but a short rest usually takes care of that. I have minor skin issues, and my hair has thinned a bit, but those are things that I'm willing to deal with to have my life back. I can take my grandbaby on walks in her stroller and not be gasping for air. Nucala has been life-changing for me."

• Wee...
• September 19, 2019

For Eosinophilic Granulomatosis with Polyangiitis "Late onset asthma about 18 years ago, polyps, heart valve problems, high eosinophilia, pericarditis for over five years. Given Nucala for both severe asthma and Churg-Strauss. Has helped wheezing and breathing. Have noticed attacks, immune, and weakest part of body. Constant bladder infections, headaches, sore throats. Am exhausted all the time. In stage two of disease. Like any other meds, helps one thing, causes another. Have had nine times, hoping to put disease in remission."

• Wee...
• Taken for 2 to 5 years
• February 5, 2021

For Asthma "I had an allergic reaction to Xolair and have been on Nucala for about 3 years now. I always got headaches, felt tired a day or two after I received the injection, but today was different. I got the injection Wednesday, today is Thursday, and when I got home, I wasn't feeling good, real tired, short of breath, my heart was racing, itchy throat, pain in my shoulder and up my neck where I received the shot, which I usually feel, chest is sore and my oxygen was 92-93. I went to the ER, and the doctor told me not to get the injection anymore. He did a chest x-ray and gave me breathing treatments. The injection really gave me a better quality of life, but I am scared to get it again, unsure what to do. My pulmonologist is supposed to call me back Saturday and we're supposed to talk about getting the injection again or not. With Xolair, he said I could die if I get it again, so of course, I said no, I don't want it. Has anyone else experienced this, getting Nucala?"