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Medications for Eosinophilic Granulomatosis with Polyangiitis

Other names: Churg-Strauss Allergic Angiitis; Churg-Strauss Syndrome

About Eosinophilic Granulomatosis with Polyangiitis

Churg-Strauss syndrome (allergic angiitis or granulomatosis) is rare disorder marked by blood vessel inflammation. This inflammation causes injury to organ systems – the most commonly involved are the lungs, nose, sinuses, skin, joints, nerves, intestinal tract, heart, and kidneys. A main feature of CSS is that all patients have had a history of asthma and/or allergies. The cause is unknown although the immune system is involved. Patients who have CSS feel generally ill and fatigued, have fevers, or have a loss of appetite and weight. Other specific symptoms depend on the organs or diseases involved. There's no cure for Churg-Strauss syndrome, but certain medications may help even people with serious symptoms achieve remission.

Drugs used to treat Eosinophilic Granulomatosis with Polyangiitis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Nucala 5.8 9 reviews
Rx N N

Generic name: mepolizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, side effects

For professionals: Prescribing Information

mepolizumab 5.8 9 reviews
Rx N N

Generic name: mepolizumab systemic

Brand name:  Nucala

Drug class: interleukin inhibitors

For consumers: dosage, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Learn more about Eosinophilic Granulomatosis with Polyangiitis

IBM Watson Micromedex

Mayo Clinic Reference

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.