Skip to main content

Fasenra Side Effects

Generic name: benralizumab

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jul 18, 2022.

Note: This document contains side effect information about benralizumab. Some dosage forms listed on this page may not apply to the brand name Fasenra.

Applies to benralizumab: subcutaneous solution.

Serious side effects of Fasenra

Along with its needed effects, benralizumab (the active ingredient contained in Fasenra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benralizumab:

Less common

  • Fast heartbeat
  • fever
  • hives, itching, or skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled breathing or swallowing

Incidence not known

  • Cough
  • dizziness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • unusual tiredness or weakness

Other side effects of Fasenra

Some side effects of benralizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • body aches or pain
  • congestion
  • dryness or soreness of the throat
  • runny nose
  • tender, swollen glands in the neck
  • voice changes

For Healthcare Professionals

Applies to benralizumab: subcutaneous solution.


Frequency not reported: Anaphylaxis, angioedema[Ref]


Frequency not reported: Immunogenicity[Ref]


Common (1% to 10%): Injection site reactions (e.g., pain, erythema, pruritus, papule)[Ref]


Common (1% to 10%): Pharyngitis (bacterial, viral, or streptococcal), cough[Ref]


Common (1% to 10%): Pyrexia[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


Common (1% to 10%): Urticaria, rash[Ref]

Frequently asked questions


1. "Product Information. Fasenra (benralizumab)." Astra-Zeneca Pharmaceuticals (2017):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.