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Granulomatosis with Polyangiitis

Medically reviewed by Drugs.com. Last updated on Nov 3, 2024.

What is granulomatosis with polyangiitis (GPA)?

GPA is a rare blood vessel disease where your blood vessels are inflamed. Small lumps called granulomas may also form when the cells lining your blood vessels die. This can cause a decrease in blood flow to your organs, most commonly your respiratory tract, lungs, and kidneys.

What may cause GPA?

The exact cause is not known. Healthcare providers think that an abnormal immune response, such as an infection, may lead to GPA.

What are the signs and symptoms of GPA?

You may have any of the following:

How is GPA diagnosed?

How is GPA treated?

Treatment options

The following list of medications are related to or used in the treatment of this condition.

View more treatment options

Call your local emergency number (911 in the US) if:

Call your doctor if:

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.