OxyContin Interactions
There are 617 drugs known to interact with OxyContin (oxycodone), along with 16 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 214 are major, 400 are moderate, and 3 are minor.
- View all 617 medications that may interact with OxyContin
- View OxyContin alcohol/food interactions (1)
- View OxyContin disease interactions (16)
Most frequently checked interactions
View interaction reports for OxyContin (oxycodone) and the medicines listed below.
- aspirin
- aspirin
- baclofen
- baclofen
- clonazepam
- clonazepam
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- gabapentin
- gabapentin
- levothyroxine
- levothyroxine
- lisinopril
- lisinopril
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- metformin
- metformin
- omeprazole
- omeprazole
- prednisone
- prednisone
- tizanidine
- tizanidine
- trazodone
- trazodone
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
OxyContin alcohol/food interactions
There is 1 alcohol/food interaction with OxyContin (oxycodone).
OxyContin disease interactions
There are 16 disease interactions with OxyContin (oxycodone) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
More about OxyContin (oxycodone)
- OxyContin consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (294)
- Drug images
- Latest FDA alerts (3)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Tylenol
Tylenol is a pain reliever and a fever reducer used to treat many conditions such as headaches ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug used to treat pain and inflammation associated ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
