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User Reviews for Naltrexone

Also known as: Vivitrol

Naltrexone has an average rating of 8.0 out of 10 from a total of 522 ratings on Drugs.com. 76% of reviewers reported a positive experience, while 14% reported a negative experience.

Condition Avg. Rating Reviews Compare
Alcohol Dependence  
8.6
299 reviews 5 medications
Opiate Dependence  
7.4
158 reviews 10 medications
Fibromyalgia  Off-label
7.1
61 reviews 21 medications
Trichotillomania  Off-label
7.0
3 reviews 3 medications
Smoking Cessation  Off-label
1 reviews 18 medications
Summary of Naltrexone reviews 8.0 522 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Naltrexone

Anonymous · March 30, 2020

Vivitrol (naltrexone) for Alcohol Dependence: “Hi, I'm a 40 year old that has been a drinker since age 13. I've drank hard liquor, malted liquor, beer, anything alcoholic. I've used drugs in the past, a lot, however booze is always my gas to get the motor going. The only times I did not drink was when either I was in prison, unsuccessfully rehab stays, or detoxes. Other than that, I was drinking. I wanted to try this injection, because I had tried naltrexone pill form in the past and I got massive migraines from it. Needless to say I been out of prison and off parole for 7 years, got my own apartment but kept drinking, and getting into scuffles without police in the middle. I drank my last drink on a Monday, and called to ask for this shot Tuesday. I got it And the rest is history. I had no symptoms. No withdrawals, no side effects, no bad dreams, nothing but the good things that came with it. Sobriety, and free of cravings, free of thoughts, free of desires.”

10 / 10
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Rapelje · Taken for 6 months to 1 year · December 15, 2020

For Fibromyalgia: “In response to BP, I’ve learned that Naltrexone is most effective at lower dosages for Fibromyalgia, but the smaller dosages have to be compounded individually. Most towns/cities have compounding pharmacies or hospital pharmacies capable of compounding for you. My ‘script runs about $45 for 90 pills. I started at .75mg for a week, 1.5mg. for a week, then 3.0mg, and finally, 4.5mg. By increasing it gradually over a month’s time, I avoided much of the “new med” issues. The doc said we could go up to 9mg, if necessary. I can’t take opioids nor narcotics, so Naltrexone has been a Godsend for me. I have Lupus, Fibromyalgia and severe arthritis in my neck. Naltrexone is the only drug that has worked - and has worked without the nasty side effects of other drugs. Hope this info helps!”

9 / 10
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Cherrypie · June 16, 2019

Vivitrol (naltrexone) for Alcohol Dependence: “I have struggled with alcohol for 15 years. Major depression & severe anxiety. Nothing took the craving away. I am surrounded by alcoholics & my husband is an alcoholic. I got a promotion at work and one morning I went to work and thought I was going to die. I couldn't take it anymore & told them I had to go to the hospital. I detoxed at a great facility. They were incredible. They saved my life. I had previously been asked if I wanted the vivitrol shot & I declined. This time I begged for the shot. Best decision I ever made! I got my 4th shot last week. I have no cravings. I have mental clarity. I'm off antidepressants. I have lost 27 pounds. Side effects...my body aches but I'll take it. I have no appetite so when I do eat. I eat healthy. Except for chocolate. I am extremely grateful for Vivitrol. I know it has saved my life. I actually died on my birthday a couple years ago from severe alcohol withdrawal & critically low potassium. Didn't stop me from drinking again. Vivitrol did.”

10 / 10
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MJ · May 21, 2020

For Fibromyalgia: “LDN saved my life. I spent years thinking I just had bad depression & PTSD thanks to all the trauma. At 25 though, I got hit with a wave of intense brain fog. I couldn't read a paragraph & retain the information, leaving the oven on, front door unlocked, driving my marriage into the ground because I wouldn't remember conversations, getting lost in the grocery store, had to withdraw from my college classes. It was this bad for nearly a year. Getting the Fibro diagnose only tanked my moral. I felt like like an 85 year old with dementia, & have a disease most people think is BS. Yay! I've been on LDN for 3 months now & found those 50 IQ points I had lost in the fog. I'm no longer an elderly young person! I'm reading books, back in school & getting 100% on assignments. I'M BACK & the only change I made is LDN & while I never cared about the fibro pain ("pain is weakness leaving the body, oorah!"-my favorite drill sergeant) the flare ups are less intense, shorter, & easier to manage.”

9 / 10
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Jarrod · Taken for less than 1 month · August 8, 2020

For Alcohol Dependence: “I have been a heavy drinker - carton a day for 10 years, then a little less as I got older. 25 years of solid everyday drinking. Blackouts are normal - I do shots till I am muted. Locked up 4 tines drunk and disorderly - AA for 22 weeks - failed. Get the picture ! day 5 of naltrexone- had to cut my 50 mg pill into 1/4 . I was whacked as on a full pill for 2 days ! Could not function at work on it - Forced to drink last night by my work mates at a party and my beer tasted weird and it made me queasy managed to down 3 and I left the party. Everyone was shocked as I am normally an animal and last one standing - I don’t feel like a drink at the moment ! - so far so good - my advise only take a portion of the pill if it whacks you out too much - good luck all my fellow comrades”

9 / 10
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lollypop8381 · Taken for less than 1 month · June 2, 2021

For Alcohol Dependence: “I am on day 7 of 50mg Naltrexone for alcohol addiction/binge drinking. Day one - four I had one beer which I actually struggled to drink. I drank them so slowly and with such disgust they actually got warm. Why I continued to drink them? I'm an alcoholic, who knows? Day 5 and 6 I actually did not drink anything and had no desire to drink. I am on day 7 and I really hope this pill continues to work its wonders. I have had mild side effects. Mostly a little nausea and a spaced out in the head type feeling but nothing that isn't manageable. I'm very please with this drug and wished that I had started it sooner.”

9 / 10
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purplekelle · Taken for 1 to 2 years · March 16, 2019

For Fibromyalgia: “I have suffered with mild/moderate level neuro-inflammation for over 30 years. This includes severe fatigue, brain fog, heart arrhythmia, visual disturbances and more. Never in these years has anything helped my ME/CFS as well as LOW dose naltrexone. I started at 0.5mg and raised it 0.5mg every two weeks until I got to 4.5mg/day. 30 minutes after my first dose, my brain fog/headache completely disappeared! Nothing has done that for me before. I share my whole story online and I recommend LDN (Low-dose naltrexone)- more info for your doctors who would prescribe it on the site LDN researchtrust if you need help figuring it out. I don't tolerate other medicines well, but this has been a lifesaver! Good luck all!”

10 / 10
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Frequently asked questions

sober52 · Taken for less than 1 month · May 24, 2020

For Alcohol Dependence: “I was drinking from morning till night when not working. This had gone on for about 2 years when it started to become unmanageable. I admitted myself to rehab. Went thru detox for a week and then rehab for weeks. Went to thru an intensive out patient program for 3 weeks. I really tried hard for about 45 days but I felt like I was constantly craving it. I started drinking again and fell right back into the same pattern for 2 months. I began to regret and hate myself again. I decided I couldn't take it anymore and gave Naltrexone a try. 25mg 1xday. No cravings. Makes me sick thinking about it. Day 3 and still don't want a drink. I am pretty tired though but that's way better then being drunk and hungover. I highly recommend it.”

10 / 10
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TAS · March 28, 2020

For Fibromyalgia: “I have been taking Naltrexone LDN for fibro for about 2 years now. The difference is amazing, like a miracle. At 42, I felt like I was 90. My body was just inflamed and it constant pain. When I moved everything felt tight, sore and painful. My inflammation was very high and my doctor put me on 9mg of LDN to start. I was at that dose for about 9 months and my inflammation was still very high and I was also still struggling to lose weight. My doctor upped the LDN to the full dose naltrexone level of 50mg to help with the weigh tloss and it did, between the 9mg and 50mg I lost 30lbs. However, the 50mg dose was a little too high for me, as it made me so sleepy, so I dropped it down to roughly 32mg, but I take it in split doses of 16mg, 12 hours apart. That has proved to be my perfect dose. I no longer have any body aches or pains, I wake up feeling 20 again and the naltrexone gives me energy throughout the day. I also have hypothyroidism and lack of energy had been a huge problem for me as well.”

10 / 10
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Wren · August 4, 2019

For Alcohol Dependence: “I am 42, struggling with alcoholism for years but the cravings won out every time. I figured I’d eventually get cirrhosis and drink myself to death. I was starting to hate myself. Until naltrexone and the Sinclair Method. One month in and I haven’t passed out from drinking nor gotten wasted. I’m actually making plans and doing things that don’t factor alcohol. It takes 2-3 days to get through a bottle of wine now (!) I’ll drink 1 beer and feel done with drinking for the day. I went on a camping trip with friends and woke up fresh every day because I stopped drinking when everyone else did for once. My husband feels excited for our future for the first time in years. I can sense the grip of alcohol starting to let go. I feel like this pill is my miracle and I cannot for the life of me understand why the world hasn’t embraced the Sinclair Method. I feel sorry for everyone who thinks a lifetime of AA and rehab and shame and guilt is the only way to go. This naltrexone pill is literally my lifeline.”

10 / 10
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Idahogirl · February 21, 2021

For Fibromyalgia: “LDN ( low dose naltrexone) has changed my life in almost every way! Cured: fibromyalgia, rheumatoid arthritis, and Cushing disease! No more chronic pain, fatigue, or weakness. There’s no detectable testing as far as blood work and was severely disabled over a decade on multiple RA meds. LDN does not just treat it cures!!!!”

10 / 10
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bella · Taken for less than 1 month · December 30, 2019

For Alcohol Dependence: “I never in a million years would of imagined my life without a drink in my hand I have been an alcoholic now for about 6 years as the years went on my habit became worst, drinking any time of day could of been 7am , 7pm , time didn't matter but my drink sure did. When I talked to my doctor about the situation he suggested me to start taking naltrexone and I started on a dose of 25mg and now on to 50mg and wow IT REALLY works. I have been sober now for 10 days. Hey for me thats pretty damn good I've lost over 6 pounds and I feel fantastic I had absolutely no side affects except NO desire to drink and alcohol tastes like rubbish if you want a second chance and want to help yourself stop drinking then naltrexone is definitely the first step ;) I wish everyone the best of luck it truly is a miracle pill ❤️❤️”

10 / 10
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Hawkeye · October 21, 2019

Vivitrol (naltrexone) for Alcohol Dependence: “I have been sober 2 months with my first VIVITROL shot! Alcohol was my poison. Nothing could stop me from going to any convenience store to buy my daily 24 pack. Since the first day, ALL of my cravings have disappeared! I have " debated" with myself to "test" this injection, however, I immediately lost all interest. No explanation other than that! Just zero interest. After 30 years of this poison - poof!! Just like that! If you struggle with addictions of all sorts, VIVITROL is your answer!! No joke! It works!!!”

10 / 10
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Mamared · Taken for 1 to 2 years · July 27, 2019

For Fibromyalgia: “I take this for my fibromyalgia at 4.5mg dose. I had the weird night time dreams/sweats, etc at first, so I switched to taking it in the morning for the rest of the first month. After that I switched back to taking it at night because I take other medications at that time and struggled to remember my low-dose naltrexone (LDN) in the morning. It doesn’t disturb my sleep anymore and I wake up refreshed most days. If I know I’m going to have a physically taxing day, I will skip my evening dose and take it first thing in the morning. I’ve found this enables me to go all day without pain or feeling overly tired. I highly suggest people research how the drug works when deciding what time of day to take it, and before giving up on taking it. It took me 3 months to notice improvement and I’m glad I stuck with taking it. I’ll never go off.”

10 / 10
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Anonymous · Taken for 6 months to 1 year · July 6, 2019

Vivitrol (naltrexone) for Alcohol Dependence: “Imagine your favorite food. Let's say it's pizza. Now you're at your favorite restaurant that serves pizza just the way you like it. But something is different and you're just not in the mood for pizza so you order something else. That's exactly what Vivitrol is like. You can think about drinking but you're just really not in the mood for it. Also if you're an alcoholic you've probably been prescribed an SSRI by now and with those it takes weeks to start working but Vivitrol is pretty immediate as in it only takes maybe an hour two to become really effective. If you're reading this you've probably tried all the unless things out there and it just can't reach that itch. Vivitrol is about as close to a magic shot as you're going to get for alcohol problems”

10 / 10
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MHAP · January 27, 2020

For Alcohol Dependence: “I was prescribed Naltrexone 3 days ago and I literally cannot believe the difference it has made to my life in such a short time!! I have been drinking 2 bottles of wine every night for over 10 years and close to that for 20 years before that. I had a miserable lonely life, doing nothing but working and closet drinking. I didn’t see anyone and ignored my kids. I just lived for my next drink, regardless of what it was doing to me. I had resigned to the fact this was how I would die - and the sooner the better. I finally feel free, and it has been no effort at all!! I have zero desire to drink and even my appetite has been suppressed! (Great side effect!) I am enjoying my kids and can get in my car whenever! I had moderate nausea on the first day, but my Dr prescribed anti nausea medicine which quickly fixed that. I have had a little trouble staying asleep but not too bad. I am taking 25mg, and don’t think I will need to go to 50mg, but 25mg works.”

10 / 10
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Stuman · Taken for less than 1 month · December 8, 2019

For Alcohol Dependence: “I was a heavy (beer) alcoholic for 40 years. My new wife told me about Naltrexone and I opted to give it a try because I don't ever want to lose this amazing woman because of my drunken stupidity. I had gotten my first ever DUI in 2018 and it was most embarrassing both for my wife and myself. I started taking it Nov 2019 and that same morning after I took it, I usually would have about 2 beers when I first get up. I took the pill and of course, with a beer. I didn't feel like having another beer for several hours. I was so thirsty though and began drinking tons of water that day. My wife then introduced me to the many flavors of Gatorade (to my surprise, I love them all). It's now Dec 12/2019 and I crave maybe 2 or 3 beers a day instead of 10-12. My wife said if I can just be a casual beer drinker, she's okay with that. Me too. I feel so much better already. I had no idea how clear life really is.. when Sober. Thanks Naltrexone. You saved me and my new marriage.”

10 / 10
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More FAQ

aspengirl35 · May 11, 2021

For Alcohol Dependence: “Early I know. Took my first pill (50mg) this morning for alcohol dependence. Right away I started noticing an increased energy level, I thought at first my coffee was really good. Once I got in the car to leave for work I could really notice an energy feeling, almost too much so I knew it was the Naltrexone kicking in. I was also becoming nauseated and a little dizzy. I have a long drive to work so I was becoming concerned that I was not coherent enough to drive. However, after about 30 more minutes I started feeling fantastic! The energy feeling leveled out somewhat, nausea went away and I had a feeling of euphoria. Very happy, calm, and PAIN FREE. Just feeling in a great mood, no bad side effects.... yet. So far it has also suppressed my appetite. If this makes me feel like this every day I would want to take it forever. We will see how it does with my alcohol desire. As of now I could care less about alcohol or food. I will update the review if anything changes.”

10 / 10
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Starette · Taken for less than 1 month · September 8, 2019

For Alcohol Dependence: “3 days on Naltrexone and what a difference! I am (was) a passout drinker..drink til I pass out and then start all over once I wake up. But with Naltrexone I'm just not interested in drinking. I used to be desperate to get that booze but now it's like "Meh" don't really feel like drinking..unbelievable! I was totally addicted to alcohol..a DUI, jailtime, job loss, wrecked relationships and I still couldn't stop...til now! Naltrexone is my light at the end of a terribly dark tunnel. Many thanks to my physician who specializes in Addiction for persuading me to at least try it...Naltrexone is saving me from this terrible addiction.”

10 / 10
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GRATEFUL... · November 27, 2015

Vivitrol (naltrexone) for Alcohol Dependence: “After battling the bottle for 30 years I am so Grateful that I found this. I tried everything from AA to SMART Recovery and to be honest while each program has it's good points they did not take away that urge to drink. This did. Instantly. Vivitrol has really been a blessing because it not only blocks the urge to use but it goes the extra step of blocking the high if you do drink I was just a Garden variety alcoholic. I drank around the clock. I would even drink in the shower. The funny thing is I never bought into the disease model even while I was sober for years at a stretch. I would eventually pick up a drink because the urge, that voice, the Beast was always there. Not anymore! Vivitrol stopped the brain imbalance that MADE me drink.”

10 / 10
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Ann · Taken for 1 to 2 years · August 18, 2019

For Fibromyalgia: “Hi. It is very important to titrate VERY SLOWLY to your naltrexone dose for fibromyalgia. I had pills that were 3 milligrams. I divided it up by thirds the first two weeks then by half the second two weeks. Then divided up by thirds again taking 2/3 at a time for two weeks until I was on the whole 3 mg dose. I’ve never gone up from there. I had debilitating hip pain due to Hashimoto’s end it is go on or down to a one or two on the pain scale. It was a rough transition. It really messed up my sleep and I’m already in insomniac. I will never go without this medicine. I’m not somebody who likes to take meds. If you had a bad reaction maybe try very low-dose for a long time and slowly build up. By the way when I first got it I tried the whole dose and I was a mess. That’s why I went slow.”

10 / 10
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Kristinadarlin · July 10, 2014

For Alcohol Dependence: “I've been a active alcoholic for 10 years. Started socially. I went through treatment once and relapsed. Alcoholism for me has given me depression, anxiety, insomnia, OCD, stress, and the worse of them all racing thoughts. Classic right? I'm on day 4, but noticed the difference RIGHT away. It made me a bit queasy and in a daze of some sort, but I slept wonderfully and woke up at EASE and I have been everyday since I started. I have NO cravings whatsoever for alcohol, the thought of it actually repulses me. Anyways, I agree with everyone saying that this medication is God sent. Remaining steady with my thoughts has helped me already socially, with my kids and my job. I have happy tears to of finally found something that held onto me for YEARS”

10 / 10
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Qlder · Taken for 2 to 5 years · June 6, 2019

For Fibromyalgia: “I was on the verge of leaving my job and applying for a disability pension when I started LDN (low dose naltrexone) for fibromyalgia, it took a while to get the right dosage that works (I'm now on 6mg) but it has saved my life. It stops the pain, most days the tender points aren't tender at all. I also use 5 HTP at night for sleep and in the morning for mood, D ribose for energy, and am currently testing acetyl L carnitine for energy. Feeling extremely grateful for being virtually cured.”

9 / 10
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Hollister resident · Taken for less than 1 month · March 31, 2015

Vivitrol (naltrexone) for Alcohol Dependence: “After partying almost 30 years in a successful, trouble free life, I began taking antabuse pills a few years ago without a recovery program. I was told about vivitrol and it interested me in quitting my prescription hydrocodone, benzo, and drinking. My 1st shot was 10 days ago and it does make your mind content. I can tell the drug is wrapped around my receptors. If I where to attempt to take a drink....it feels like I already had one. Not taking pills is no big deal either. I still take a sleep aid at night and Aleve or Ibuprofen for anything else. I. Am now experiencing eating and sleeping like I've seen normal people do all my life. A spiritual feeling should come along with that for those of you who are willing to make a change.”

8 / 10
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Mendee86 · March 24, 2017

Vivitrol (naltrexone) for Alcohol Dependence: “I started going to a clinic to get extra help on top of AA. My alcohol use had gotten to a very, very dangerous level. I would flirt with sobriety through AA, getting almost to 30 days, then a bad craving would hit and I couldn't resist. Then I found out about vivitrol. After my first shot it cut my cravings down ten fold. Now 4 shots in I rarely have a craving and when I do it's manageable. This has allowed me to concentrate on my recovery without also battling cravings. I'm 95 days sober today and so grateful.”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.