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User Reviews for Naltrexone to treat Fibromyalgia

Also known as: Vivitrol

Naltrexone has an average rating of 7.2 out of 10 from a total of 57 ratings for the treatment of Fibromyalgia. 67% of reviewers reported a positive effect, while 21% reported a negative effect.

Naltrexone Rating Summary

7.2/10 average rating

57 ratings from 59 user reviews.

Compare all 30 medications used in the treatment of Fibromyalgia.

10
32%
9
25%
8
11%
7
5%
6
2%
5
5%
4
0%
3
2%
2
5%
1
14%

Reviews for Naltrexone

Rapelje · Taken for 6 months to 1 year December 15, 2020

“In response to BP, I’ve learned that Naltrexone is most effective at lower dosages for Fibromyalgia, but the smaller dosages have to be compounded individually. Most towns/cities have compounding pharmacies or hospital pharmacies capable of compounding for you. My ‘script runs about $45 for 90 pills. I started at .75mg for a week, 1.5mg. for a week, then 3.0mg, and finally, 4.5mg. By increasing it gradually over a month’s time, I avoided much of the “new med” issues. The doc said we could go up to 9mg, if necessary. I can’t take opioids nor narcotics, so Naltrexone has been a Godsend for me. I have Lupus, Fibromyalgia and severe arthritis in my neck. Naltrexone is the only drug that has worked - and has worked without the nasty side effects of other drugs. Hope this info helps!”

9 / 10
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MJ May 21, 2020

“LDN saved my life. I spent years thinking I just had bad depression & PTSD thanks to all the trauma. At 25 though, I got hit with a wave of intense brain fog. I couldn't read a paragraph & retain the information, leaving the oven on, front door unlocked, driving my marriage into the ground because I wouldn't remember conversations, getting lost in the grocery store, had to withdraw from my college classes. It was this bad for nearly a year. Getting the Fibro diagnose only tanked my moral. I felt like like an 85 year old with dementia, & have a disease most people think is BS. Yay! I've been on LDN for 3 months now & found those 50 IQ points I had lost in the fog. I'm no longer an elderly young person! I'm reading books, back in school & getting 100% on assignments. I'M BACK & the only change I made is LDN & while I never cared about the fibro pain ("pain is weakness leaving the body, oorah!"-my favorite drill sergeant) the flare ups are less intense, shorter, & easier to manage.”

9 / 10
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purplekelle · Taken for 1 to 2 years March 16, 2019

“I have suffered with mild/moderate level neuro-inflammation for over 30 years. This includes severe fatigue, brain fog, heart arrhythmia, visual disturbances and more. Never in these years has anything helped my ME/CFS as well as LOW dose naltrexone. I started at 0.5mg and raised it 0.5mg every two weeks until I got to 4.5mg/day. 30 minutes after my first dose, my brain fog/headache completely disappeared! Nothing has done that for me before. I share my whole story online and I recommend LDN (Low-dose naltrexone)- more info for your doctors who would prescribe it on the site LDN researchtrust if you need help figuring it out. I don't tolerate other medicines well, but this has been a lifesaver! Good luck all!”

10 / 10
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TAS March 28, 2020

“I have been taking Naltrexone LDN for fibro for about 2 years now. The difference is amazing, like a miracle. At 42, I felt like I was 90. My body was just inflamed and it constant pain. When I moved everything felt tight, sore and painful. My inflammation was very high and my doctor put me on 9mg of LDN to start. I was at that dose for about 9 months and my inflammation was still very high and I was also still struggling to lose weight. My doctor upped the LDN to the full dose naltrexone level of 50mg to help with the weigh tloss and it did, between the 9mg and 50mg I lost 30lbs. However, the 50mg dose was a little too high for me, as it made me so sleepy, so I dropped it down to roughly 32mg, but I take it in split doses of 16mg, 12 hours apart. That has proved to be my perfect dose. I no longer have any body aches or pains, I wake up feeling 20 again and the naltrexone gives me energy throughout the day. I also have hypothyroidism and lack of energy had been a huge problem for me as well.”

10 / 10
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Idahogirl February 21, 2021

“LDN ( low dose naltrexone) has changed my life in almost every way! Cured: fibromyalgia, rheumatoid arthritis, and Cushing disease! No more chronic pain, fatigue, or weakness. There’s no detectable testing as far as blood work and was severely disabled over a decade on multiple RA meds. LDN does not just treat it cures!!!!”

10 / 10
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Mamared · Taken for 1 to 2 years July 27, 2019

“I take this for my fibromyalgia at 4.5mg dose. I had the weird night time dreams/sweats, etc at first, so I switched to taking it in the morning for the rest of the first month. After that I switched back to taking it at night because I take other medications at that time and struggled to remember my low-dose naltrexone (LDN) in the morning. It doesn’t disturb my sleep anymore and I wake up refreshed most days. If I know I’m going to have a physically taxing day, I will skip my evening dose and take it first thing in the morning. I’ve found this enables me to go all day without pain or feeling overly tired. I highly suggest people research how the drug works when deciding what time of day to take it, and before giving up on taking it. It took me 3 months to notice improvement and I’m glad I stuck with taking it. I’ll never go off.”

10 / 10
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Qlder · Taken for 2 to 5 years June 6, 2019

“I was on the verge of leaving my job and applying for a disability pension when I started LDN (low dose naltrexone) for fibromyalgia, it took a while to get the right dosage that works (I'm now on 6mg) but it has saved my life. It stops the pain, most days the tender points aren't tender at all. I also use 5 HTP at night for sleep and in the morning for mood, D ribose for energy, and am currently testing acetyl L carnitine for energy. Feeling extremely grateful for being virtually cured.”

9 / 10
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Frequently asked questions

Ann · Taken for 1 to 2 years August 18, 2019

“Hi. It is very important to titrate VERY SLOWLY to your naltrexone dose for fibromyalgia. I had pills that were 3 milligrams. I divided it up by thirds the first two weeks then by half the second two weeks. Then divided up by thirds again taking 2/3 at a time for two weeks until I was on the whole 3 mg dose. I’ve never gone up from there. I had debilitating hip pain due to Hashimoto’s end it is go on or down to a one or two on the pain scale. It was a rough transition. It really messed up my sleep and I’m already in insomniac. I will never go without this medicine. I’m not somebody who likes to take meds. If you had a bad reaction maybe try very low-dose for a long time and slowly build up. By the way when I first got it I tried the whole dose and I was a mess. That’s why I went slow.”

10 / 10
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Memphis November 29, 2019

“I've was diagnosed with fibromyalgia in 2013. I tried the traditional medications and none helped and I suffered with horrible side effects. I stopped medical treatment in 2016 because I was so frustrated with spending money and getting no improvement. In November of this year at the advice of my primary care doctor I saw a rheumatologist. He listened and recommended the LDN. My pain level dropped tremendously. I suffered with burning aching pain in my back and legs. I've been on the medication for about 3 weeks. I really have not experienced any side effects.”

8 / 10
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Dan4354 March 8, 2019

“I got this medication from my doctor, after I was telling her the amount of alcohol I was drinking. I always had, when I was drinking or not, extreme restlessness and exhaustion in once. My muscle were hurting, I could sleep 10 hours and was not feeling rested. Could not concentrate very good, had social anxiety etc. I took 25 mg at night went to bed and.... Wow I felt like I was high. The pain gone, exhaustion gone, depression gone everything I described above were non existent anymore. I felt I had helium balloons on my arms and head. Feeling rested after 6 hours of sleep, being awake the whole day... The day feels so long now, because I can use every minute. Also I felt no desire for any drug anymore. I went out with people drinking, drank just mineral water. Impossible for me before the pill. I'm not lying. I also can't believe what happened. I am pure Bliss.. I was about 10 years like that. Now I'm free. Try this miracle drug! Highly recommended!!”

10 / 10
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Anonymous · Taken for less than 1 month April 19, 2019

“After 4 weeks of low dose naltrexone (LDN) it has reduced my Fibromyalgia pain from an 8 to about a 2-3. I have fatigue I still struggle with but it has also given me a boost in energy as well. I am able to keep my full time job that I almost had to quit and have been able to do more and more outside of work then I was for years. I’ve had Fibromyalgia for 4 years and tried many medications and this is only one that has helped. I had to go online to finally find a Dr to prescribe it. I currently take 3.0mg and is absolutely worth a try.”

10 / 10
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Peony · Taken for 1 to 6 months October 2, 2019

“Diagnosed 30 years ago with fibro. Pretty miserable. I tried antidepressants, opiates, muscle relaxers, as well as non medical therapies. For me the NDL (low dose naltrexone) gave more energy and less burning pain. Its also much less expensive than lyrica with fewer side effects.”

10 / 10
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Zaxacava February 22, 2016

“I have never been this functional before. 8 months ago my functional capacity was at 50%. All I was doing was work, recover, and burn through an excessive amount of sick, vacation, and banked time. At home I was almost zombie like. I would spend all of my time curled up on the sofa in pain, fog, or fatigue. Thanks to LDN: Today I was able to pool run for 30 min! I did laundry and sorted all of the socks. Yesterday we had friends over to hang out for the first time in ages. I was able to go to a movie. I was tired after it all but it wasn't an all encompassing thing. I flirted with my fianc”

8 / 10
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Mel999 April 2, 2014

“I have been diagnosed with Fibromyalgia for 12 years (took 5 mg of hydrocodone daily). I was able to work, function as a normal person & pain was manageable. In June I had several pulled muscles & a rotator cuff injury - pain was off the charts. The doctors in Tucson will not write pain meds under any circumstances - cut me off cold turkey and I pulled neck muscle. For 6 months my pain level was a 15 (scale of 1-10) suicidal pain with no relief in site. I was referred to country doctor in Wilcox, AZ - he said he would write me pain meds, but was I willing to try a alternate prescription that would possible get rid of my pain. I started out with 4.5mg daily at night and within 4 weeks my pain went down to around 2-3.”

8 / 10
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Jillzie · Taken for less than 1 month December 28, 2020

“I cannot believe how this med naltrexone has helped my fibro. I've tried many meds and always have side effects. The only side effect I have with this is a bit sleepiness but I take it at night. I'm still on a starting dose of 1.5 but AMAZING!!!!”

10 / 10
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Sara · Taken for 6 months to 1 year November 5, 2019

“I started low dose naltrexone (LDN) for Fibromyalgia after years of feeling like a lab rat! It is amazing I no longer feel like I am in a fog, everything is so much clearer. Pain is minimal, I have still have had an occasional flare but few and far between and mainly when I over do it. I feel like I have gotten my life back. I do take it in the morning 4.5mg because it had been causing insomnia.”

9 / 10
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Nonymus · Taken for 6 months to 1 year August 20, 2013

“Since I began taking 5 mg naltrexone at night, I fall asleep quickly, I sleep very well for 8 to 9 hours. I wake up refreshed and without pain. I no longer take antidepressants, sleeping pills, anxiety or pain medication. My mental functioning is much better but not back to Pre-CFIDS standard. I don't have normal energy or drive but my life is so much closer to normal than it was a year ago, I have no complaints. The only other medication I take is for high blood pressure. The only side effect I have is a slight headache when I wake in the morning but it ALWAYS goes away soon after I get up. I would take this medication if the only thing I got from it was good quality sleep.”

10 / 10
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More FAQ

Dr Chris Bowman May 5, 2017

“I have a patient with fibromyalgia in Kent UK who was given Low-dose naltrexone by another physician. Her energy improved and her pain reduced so much that she was able to return to working 20 hours a week. I am currently trying it on a second patient.”

9 / 10
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Arun P · Taken for 2 to 5 years November 26, 2016

“I developed a condition that had symptoms like fibromyalgia, Ms, Lupus after a surgery. I was at my worst when I discovered this drug. Low dose Naltrexone helps me a lot. I'm on 1.5 mg. I skip doses once in 3-4 days when I start feeling wired and over stimulated. Works great.. Made me feel better, helped with skin conditions no doctor able to cure. Only bad part is that it kind-of over stimulates you once in a while. Makes you feel all wired. Have to stop the dose for a day or two and it's gets normal.”

9 / 10
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Aquatina September 30, 2015

“I've been taking 4.5 mg naltrexone for about 45 days. It has helped my pain better than any thing in the 20 years I have been suffering with fibro. I still have some bad days but for now I'm seeing more good days and even a great day or two and far less bad days. Until know I was having pain everyday of my life. I had to see a many a dr and had not even heard of this medicine for fibro. I'm getting my life back on track at last.”

9 / 10
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Austin R. December 14, 2017

“This drug is a miracle drug for me. I'm currently 24. I've been living with fibromyalgia symptoms since I was 20. The very first time I took a single 4.5 mg dose of Naltrexone, I awoke 4 hours later with no pain. It did, and still does, feel like I have a whole new body now. If you have a condition that causes chronic pain, I highly suggest you give low dose Naltrexone a try. Talk to your doctor about it. I can't promise it will help everybody, but for me it has made an incredible difference.”

10 / 10
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Di724 · Taken for less than 1 month November 12, 2020

“I just started low dose naltrexone 1.5 for Fibromyalgia (FM) I immediately saw a difference. No more body pain. At first I thought could I just be having a good week without much pain . But after two weeks I can't believe I good I feel. For 6 yrs I was in pain everyday. I took motrin everyday, until I had an AFib episode. Now I can't take any NSAID's. I'm so happy my doctor prescribed me this. I feel like I'm 40 again. I'm now 54 and I suffered for 6 yrs not know what was wrong with me.”

10 / 10
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Pdlgrl · Taken for less than 1 month June 15, 2019

“I was so looking forward to starting Naltrexone for my fibromyalgia and hoping to eventually get off of my steroid, Aleve, azathioprine & gabapentin. But I began to gradually feel worse with joint and muscle pain on the 1.5mg dose. When after 2 weeks increased to 3mg and widespread pain was off the chart, laid in bed at night moaning & crying in pain. I stopped it the next day and have been feeling better. Thinking about restarting at 1mg and taking in daytime instead of pm. So very disappointed....”

1 / 10
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Greg in OR March 17, 2016

“I have Complex Regional Pain Syndrome/Regional Sympathetic Distrophy .I started LDN (Low Dose Naltrexone, 4.5mg) during a Stanford double blind trial in January 2016 and received a months supply. During the first week I felt some of the muscle cramping associated with Naltrexone but that and my nerve pain subsided after about a week. The next three weeks sailed by and my activity level increased as I was essentially free of CRPS/RSD nerve pain. The chronic pain in my lower back was significantly decreasing too. When my supply ran out I experienced some of the CRPS/RSD pain but not at the level I'd had before. That wasn't the case with my chronic lower back pain and that came rearing back. It was a month before my Dr could get me the compounded LDN. Again, my pain has dissipated. Weening off Gabapentin soon!”

9 / 10
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BP November 18, 2020

“I've had Fibromyalgia for about 7 years. I've tried everything and had all but given up. I happened to see info online about LDN (low dose naltrexone). I asked my doctor about it and she wrote a script but said it probably wouldn't do anything. But I insisted...desperate to try anything. However, it was for 1/2 of a 50mg tablet once per day. I felt like I had done a gram of cocaine. 2-3 hrs of sleep per night, major anxiety, heart racing etc. Couldn't focus, hands shook etc. I stuck with it for one week when I realized, my pain had dropped SIGNIFICANTLY for the FIRST time in about seven years. Thrilled at he results I had to figure out how to continue the medication but get rid of the side affects and get some sleep. I called the doc to ask what I could do as the online info said it said LDN should be 1.5 mg. She said it only came in 50 mg and I'd have to get the suggested low dose from a "compounding" pharmacy. I have no idea how to do that. Can anyone help?”

8 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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