Comparing Fluoxetine vs Naltrexone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Fluoxetine	Naltrexone	Enter another drug to compare

Fluoxetine

Naltrexone

Prescription only

Fluoxetine may be used for the treatment of certain types of mood disorders and also some eating disorders. It is more likely to cause insomnia than drowsiness. Taking fluoxetine with other... View more

Prescription only

Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction. People taking naltrexone need to have completely stopped taking all types of opioids... View more

More about Fluoxetine

More about Naltrexone

Ratings & Reviews

Fluoxetine has an average rating of 7.3 out of 10 from a total of 2234 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect.

Naltrexone has an average rating of 7.9 out of 10 from a total of 602 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 16% reported a negative effect.

View all 2234 reviews

View all 602 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Anxiety (17.1%)
Insomnia (8.5%)
Tiredness (7.3%)
Nausea (7.2%)
Sexual dysfunction (6.6%)
Depression (6.3%)
Loss of appetite (5.6%)

View all Fluoxetine side effects

Nausea (8.1%)
Anxiety (7.1%)
Tiredness (6.5%)
Depression (6.0%)
Insomnia (5.6%)
Fatigue (5.0%)
Headaches (4.8%)

View all Naltrexone side effects

Drug Class

Selective serotonin reuptake inhibitors

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	20 mg
Per unit^*	$0.18
Cost^*	$17.97

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Quantity	20 each
Strength	50 mg
Per unit^*	$1.75
Cost^*	$34.97

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Dosage Forms

Oral capsule
Oral delayed release capsule
Oral solution
Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

210 hours

10 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 682 drugs are known to interact with Fluoxetine:

165 major drug interactions (620 brand and generic names)
495 moderate drug interactions (2127 brand and generic names)
22 minor drug interactions (92 brand and generic names)

A total of 352 drugs are known to interact with Naltrexone:

34 major drug interactions (160 brand and generic names)
318 moderate drug interactions (1321 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of FLUoxetine such as dizziness, drowsiness... View more

Naltrexone may cause liver problems, and using it with other medications that can also affect the... View more

Disease Interactions

First Approval Date

December 29, 1987

November 20, 1984

WADA Class View classifications

N/A

More Information

Patient Resources

Fluoxetine uses

Naltrexone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Fluoxetine vs Naltrexone

See also:

Vraylar

Lexapro

Rexulti

Abilify

Zoloft

Seroquel

Xanax

Prozac

Cymbalta

Wellbutrin

Further information

Comparing Fluoxetine vs Naltrexone

See also:

Further information

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