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Topiramate for Smoking Cessation User Reviews

Brand names: Topamax, Trokendi XR, Eprontia, Qudexy XR

Rating: 7.5

Topiramate has an average rating of 7.5 out of 10 from a total of 6 reviews for the off-label treatment of smoking cessation. 67% of reviewers reported a positive experience, while 17% reported a negative experience.

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  • GBa...
  • Taken for 1 to 6 months
  • April 9, 2020

Topiramate "I was prescribed Topamax for migraines, but because this drug treats so many conditions, it had several unintended benefits. I've been on it now for about 2 months and have cut my vaping in half, lost about 2 inches from my waist, and reduced nerve pain caused by neuropathy in my legs. It actually does better for these conditions I have than for migraines, but does help with them as well. There are some nasty side effects in the first few weeks, so keep that in mind if you are prescribed this med for any reason, they should dissipate with time. I call it the do-all drug because there are about a dozen off-label uses for it. I enjoy vaping and wasn't happy, but it is saving me money! For smoking, the main study shows that about 40% are able to abstain for over 2 years. I smoked for 25 years before vaping the last 10, and it is very effective in curbing my cravings, even giving me a sense of aversion to the vaping experience."

8 / 10
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34 Report
  • sup...
  • Taken for 1 to 6 months
  • December 23, 2015

Topiramate "Horrific experience! It was working, but had to stop to protect sanity. Side effects were so awful that I give it a '2' rating, despite the effectiveness of quitting, a '9'. Piece of cake to reduce by half, in a matter of days, with zero effort. 46-year smoker. Had to stop before I ever reached full dosage. Almost went to the ER to have myself admitted for psych treatment. (Also lost 20 lbs. in one month, with no effort.) Trust me - I would have loved to have stayed on it. Some effects - mild paranoia, visual and auditory hallucinations, cry at the drop of a hat, intense sense of insecurity, inadequacy, fear of loss of self-control. 3 months later, still smoking about 25% less and 10 lbs loss. Other side effects I can't recall, except acne and weird skin rash."

2 / 10
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26 Report
  • Moo...
  • September 3, 2014

Topiramate "This slows down my smoking, but I haven't quit yet. It puts me in a better mood, and Mom said it's to lose weight, but I don't think so. The one to lose weight is phentermine. I take Topamax 100 mg twice a day, atenolol at night, and Klonopin at night. Atenolol sleeps my body, and Klonopin sleeps my mind, and it makes me dream really good, like the show Fat Guy Stuck in Internet. It just puts you in your fantasy at night."

8 / 10
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26 Report

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  • Uni...
  • Taken for 10 years or more
  • September 27, 2021

"I was prescribed topiramate for epilepsy and have been on it for 10 years. I quit smoking within 2 weeks of starting the medication and have hated smoking since. Cannot even smoke 1 cigarette, and I used to be 30 a day. I wouldn't recommend it purely for smoking cessation, but it is a definite plus point."

10 / 10
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4 Report
  • Kha...
  • Taken for less than 1 month
  • January 18, 2025

"I already feel completely turned off by the thought of smoking just two days on this medication, which was quite the opposite of how I was before. Also, my mood and energy feel so much better; positive self-worth. No side effects besides it helping me to fall asleep at night, waking up more refreshed. I would highly recommend this medication for anyone struggling with mood disorder, anxiety, and depression as well. 10/10."

10 / 10
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  • Lil...
  • Taken for less than 1 month
  • September 15, 2016

"I'm probably a very rare case. I'm being prescribed Topamax 25 mg at night as needed for sleep through the withdrawal of a prescribed pain medicine from a car accident. It is being prescribed only temporarily for two months. After reading all of these reviews, I am now terrified of hair loss, as I have grown my hair to donate for almost 20 years now. I have always had very thick, wavy/curly hair and felt others could benefit from it and liked giving back. Can anyone please give their input on if they think the temporary use of this medication will affect my hair? Thank you so much in advance."

7 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.