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When's the best time of day to take Topamax?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Dec 22, 2020.

Official Answer

by Drugs.com

Key Points

Topamax (topiramate) is taken alone or with other medicines to control certain types of seizures due to epilepsy and for the prevention of migraine headaches. When taken twice a day, the medicine is usually taken in the morning and evening. When increasing your dose at the beginning of treatment, your dose may be taken only at night for a short while.

Topamax is classified as an anticonvulsant (seizure) medication, but is prescribed for other conditions such as migraine. It is available as a generic option and can save you money. Copay cards are also available.

When you first start treatment, you will start with a low dose of Topamax and slowly increase to the amount needed to control your seizures or migraine and to help limit side effects. Your dose is not usually increased more than once per week.

Topamax can cause drowsiness, dizziness and slowed reactions, so use caution when using this medication. Do not drive, operate machinery or engage in other potentially harmful activities until you know how you will respond to the medicine. Topamax can slow your thinking and motor skills, and may affect your vision.

Topamax used alone for seizures (partial-onset seizures and primary generalized tonic-clonic seizures):

  • Adults and children 10 years of age and older usually start taking Topamax twice a day, in the morning and in the evening. You start with a low dose of Topamax and slowly increase to the amount needed to control your seizures.
  • In children 2 to 9 years of age, treatment may begin with one dose given in at night. After one week, the doctor may increase the dose and give as two doses per day based upon how well the medicine is tolerated and the results. Doses in this age group are based on weight.

Topamax used with other medicines for seizures (partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome):

  • Adults 17 years of age and older usually start taking Topamax once or twice a day at a lower dose, and their dose is slowly increased to reach the amount needed to control your seizures.
  • In children 2 to 16 years of age treatment should begin with one dose given at night for the first week. After one week, the doctor may then increase the dose and give as two doses per day based upon how well the medicine works for you and is tolerated. Doses in this age group are based on weight.

Topamax used to prevent migraine headaches:

  • Adults and adolescents 12 years of age and older initially take Topamax as one dose at night for one week. After one week, the dose can be slowly increased and given as two doses per day, in the morning and evening.
  • Your doctor can determine your dose based upon how well the medicine works for you and how well you tolerate it.

Topamax dosage (in more detail)

Should I take Topamax with food?

You can take Topamax with or without food. The tablets are bitter so do not break, crush or split them. Do not drink alcohol while taking Topamax. Drink plenty of fluids like water while taking Topamax.

Topamax side effects (in more detail)

Other brand names for topiramate include Trokendi XR, Topamax Sprinkle (discontinued), and Qudexy XR.

This is not all the information you need to know about Topamax (topiramate) for safe and effective use. Review the full Topamax information here, and discuss this and any questions you have with your doctor or other health care provider.

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