When's the best time of day to take Topamax?
Key Points
Topamax (topiramate) is taken alone or with other medicines to control certain types of seizures due to epilepsy and for the prevention of migraine headaches. When taken twice a day, the medicine is usually taken in the morning and evening. When increasing your dose at the beginning of treatment, your dose may be taken only at night for a short while.
Topamax is classified as an anticonvulsant (seizure) medication, but is prescribed for other conditions, too, such as migraine. It is available as a generic option which may save you money. Copay cards from the manufacturer are also available.
When you first start treatment, you will start with a low dose of Topamax and slowly increase to the amount needed to control your seizures or migraine and to help limit side effects. Your dose is not usually increased more than once per week.
Topamax can cause drowsiness, dizziness and slowed reactions, so use caution when using this medication. Do not drive, operate machinery or engage in other potentially harmful activities until you know how you will respond to the medicine. Topamax can slow your thinking and motor skills, and may affect your vision.
Topamax used alone for seizures (partial-onset seizures and primary generalized tonic-clonic seizures):
- Adults and children 10 years of age and older usually start taking Topamax twice a day, in the morning and in the evening. You start with a low dose of Topamax and slowly increase to the amount needed to control your seizures.
- In children 2 to 9 years of age, treatment may begin with one dose given in at night. After one week, the doctor may increase the dose and give as two doses per day based upon how well the medicine is tolerated and the results. Doses in this age group are based on weight.
Topamax used with other medicines for seizures (partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome):
- Adults 17 years of age and older usually start taking Topamax once or twice a day at a lower dose, and their dose is slowly increased to reach the amount needed to control your seizures.
- In children 2 to 16 years of age treatment should begin with one dose given at night for the first week. After one week, the doctor may then increase the dose and give as two doses per day based upon how well the medicine works for you and is tolerated. Doses in this age group are based on weight.
Topamax used to prevent migraine headaches:
- Adults and adolescents 12 years of age and older initially take Topamax as one dose at night for one week. After one week, the dose can be slowly increased and given as two doses per day, in the morning and evening.
- Your doctor can determine your dose based upon how well the medicine works for you and how well you tolerate it.
Related: Topamax dosage (in more detail)
Related questions
- Can you stop taking Topamax suddenly?
- Does topiramate cause hair loss?
- How long do you stay on Topamax for migraines?
Should I take Topamax with food?
You can take Topamax with or without food. The tablets are bitter so do not break, crush or split them. Do not drink alcohol while taking Topamax. Drink plenty of fluids like water while taking Topamax.
Learn more: Topamax side effects (in more detail)
Other brand names for topiramate include Trokendi XR (a long-acting form), Topamax Sprinkle (discontinued), and Qudexy XR (also long-acting).
This is not all the information you need to know about Topamax (topiramate) for safe and effective use. Review the full Topamax information here, and discuss this and any questions you have with your doctor or other health care provider.
References
- Topamax (topiramate). Product Labeling. Revised June 2020. Janssen Pharmaceuticals, Inc., Titusville, NJ. http://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/TOPAMAX-pi.pdf
Read next
How long does it take for Topamax to start working?
It may take 8 to 12 weeks for you to see the full effect of Topamax on your migraine headaches. In clinical studies, some people had fewer headaches after 4 weeks of treatment. In the treatment of epilepsy, Topamax is also started slowly and the dose is increased over a 6-week period. Continue reading
How long does Topamax stay in your system?
Topamax stays in your system for approximately 4 to 5 days after the last dose, but this may vary depending on personal factors, such as your age, weight, dosage, and what other medications you currently take. This estimate is based on the half-life of Topamax which is about 21 hours and experts agree that it takes up to 5 half-lives for a drug without active metabolites to be completely removed from the body. A drug’s half-life is the time it takes for 50% of that drug to be removed from the body. Topamax does have some metabolites, but these are not considered active and only make up about 5% of an administered dose. This means it takes 84 to 105 hours for Topamax to leave your body. Continue reading
Is Topamax a controlled substance?
Topamax is not classified as a controlled substance under the U.S. Controlled Substances Act (CSA). Topamax is an anticonvulsant (seizure) medication, but is also prescribed for other conditions such as prevention of migraine. It may causes side effects like confusion, drowsiness, dizziness, or blurred vision. Know how Topamax may affect you before driving or performing other hazardous activities. Continue reading
Related medical questions
- Are Topamax and Trokendi XR the same thing?
- Does topiramate cause weight loss?
- How does Trokendi XR help with weight loss?
- What is topiramate used to treat?
- What not to take with topiramate?
Drug information
- Topamax Information for Consumers
- Topamax prescribing info & package insert (for Health Professionals)
- Side Effects of Topamax (detailed)
Related support groups
- Topamax (99 questions, 697 members)