Skip to Content

User Reviews for Divalproex sodium

Also known as: Depakote, Depakote ER, Depakote Sprinkles

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Divalproex sodium.

Filter by:
Condition DownUp Reviews Compare Avg. Ratings DownUp
Hyperekplexia 1 reviews 8 medications
   
10
Borderline Personality Disorder 1 reviews 0 medications
   
9.0
Mania 23 reviews 15 medications
   
7.8
Epilepsy 56 reviews 41 medications
   
7.1
Bipolar Disorder 164 reviews 29 medications
   
6.4
Migraine Prevention 61 reviews 29 medications
   
6.2
Summary of Divalproex sodium reviews 306 reviews 7.8

Reviews for Divalproex sodium

Sort by:

For Bipolar Disorder: "I can't rate it yet but I gave it a 5 because it's been about 5 days. I've noticed a calm relax feeling. Normally after I exercise, I still have energy. Since I've started to take it, I've noticed a good calm relax tired feeling. Not a drowsy tired, which is good. Also, I'm noticing an attitude switch for the good. As for weight gain, nothing yet and I hope it stays that way. I'm eating much better and exercising more to balance just in case. I definitely feel a change for the good. Hopefully this is a fix until I can do it off medicine. If not, it is what it is. I'll keep an open mind. Let me know if anyone has anything different."

   
5.0

Joseph Robinson Jr September 18, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Migraine Prevention: "I've been getting migraines since I hit 30 and they just kept getting worse each year. My neurologist had my on several drugs that seemed to work for a time before they stopped working. Finally I was put on Depakote 2 months ago and it's been fantastic! In just over 8 weeks I've only had a single migraine when normally I'd have 3-5 a week and so far I don't seem to be suffering from any side effects. I can finally work and have an actual social life again!"

   
10

Adam J (taken for 1 to 6 months) September 4, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Bipolar Disorder: "Love this medication, after 2-3 years of severe long lasting manic episodes finally decided to take meds full time. Hardly any side effects, very hungry, simply eat normally and you wont put weight on, the medication doesn't make you fat, eating does. Occasionally very tired and my stomach from time to time gets a little funny, just take with lots of water and food. Very calm, can concentrate, no racing thoughts, level, basically gave me my life back, works well at 750 even though I'm 80kgs, Dr upped me to 1000mg but felt too sedated so dropped back down. I move to 1000mg if I feel like I'm starting to drift a little for a few weeks then move back. However, this is the 7th med I have tried, all others have failed, never write one med off"

   
9.0

qwertyazsxdc (taken for 5 to 10 years) August 26, 2017

2 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote ER (divalproex sodium) for Bipolar Disorder: "I started Depakote ER 2000mg at bedtime about a year ago after decades of ineffective treatment for depression and anxiety. Depakote proved that I was misdiagnosed: it quickly alleviated my psych. symptoms and allowed me to reduce Xanax XR dose by half and eliminate PRN Xanax. I haven't experienced the weight loss side effect, but did lose a lot of hair at first. The hair seems to be thickening up now. I would give it 10 stars except for the hair loss."

   
9.0

LAGuy (taken for 1 to 2 years) August 14, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Migraine Prevention: "I have been experiencing migraine from my teens. It has peaked in the middle age. After retirement it has again started viciously, the neurologist said it is because of pill pooping out. Tried propronolol, topiramate etc etc and even tried valproatete. Finally I tried divalporex ER 500 within days the migraine episodes came down and migraine if any does not progress into throbbing episodes requiring triptans. Gladly it goes away like a normal headache."

   
8.0

Partha vu2GPS (taken for 1 to 6 months) August 9, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Epilepsy: "I used to have a wonderful smart son. About 12 years ago, I noticed changes starting to take affect in his life. He was becoming agitated, he was loosing his memory, he had no energy. I was told this was due to his having so many seizures. I just this week, after having a really bad week a few weeks ago, the doctor decided to take him off of this medication in a hospital controlled setting. After one day of not taking this medication, I am starting to see the personality of my son come back. He had gotten to the point that he made terrible decisions, he was depressed often, he was confused and was loosing his memory and his ability to talk and remember words. I'm sorry, but the benefits of controlling seizures was not worth this."

   
2.0

J A J July 24, 2017

2 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Migraine Prevention: "Horrible! I was on it for a month, and quit immediately. I have migraine with aura. My neurologist told me a secret behind closed doors cause he was a cool dude. He said get off all the crap and once the aura comes chug two beers and it will disappear no aura no headache. He swore by it and so do I."

   
1.0

Craigsugarhill (taken for 1 to 6 months) July 14, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Epilepsy: "Have taken this med for 28+ years with no seizures during this time. I have experienced no side effects except that my hair has become very curly. Lots of compliments! No down side. I am seizure free. No other med has worked for me."

   
10

Heroncrest July 14, 2017

1 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Epilepsy: "My husband took this for a week and he turned into a unmotivated, angry, heart palpitating, paranoid Zombie. He had no relief for his headache and had tremors so bad he could not hold a fork to eat. Stomach pain, loss of appetite, hair falling out and left arm pain, to name a few more...I don't know why any doctor would order this for brain tumor pain. It is just awful. This drug may work for others but for pain it's useless..."

   
1.0

Anonymous (taken for less than 1 month) May 30, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "So weird everyone complains of weight gain. This drug (divaproex sodium) makes me lose weight to the point it's actually a bit alarming. Appetite completely gone. I've stopped and started 3-5 times as I never take anything more than a year without stopping. Every time I take it like this week for example I started at 151 pounds 5"7 female. I don't work out or exercise ever and have dropped 12 pounds in 3 days. It actually usually gets so bad I have to go talk to my doctor about my weight loss. I can stomach food but it comes out in liquid form within 15 mins and clears my system. This drug is a major weight loss drug from me. I know everytime I start it it's a given I will be losing 10 pounds minimum. Good for mood."

Anonymous (taken for less than 1 month) May 19, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "After two valiant attempts to get past the adverse effects, I'm finished with Depakote. The first attempt lasted a week; as it can exaggerate the effects of other meds, I became so drowsy I couldn't drive. For the second attempt, it wasn't combined with any other medication and lasted 3 weeks. I felt continually agitated and anxious, began to quickly gain weight, had terrible gas and was going to the bathroom 4-5 times a day. Additionally, my hair began to fall out so quickly, even my husband noticed (and he's NOT very observant!). The most disturbing symptom was the frequent presence of pronounced, irregular heart beats and at least one near-syncopal episode. All this in just 21 days- thanks but no thanks!"

   
2.0

Undun (taken for less than 1 month) May 12, 2017

1 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Migraine Prevention: "If you want to sleep a lot, as in all day long and gain lots of weight, enjoy. I am listless, and have pre-diabetes now. "

   
3.0

depabie (taken for 1 to 2 years) May 6, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Borderline Personality Disorder: "It helps with the intense mood swings, negative emotions are less severe. On an 800mg a day dose, half in the morning, half at night."

   
9.0

Anonymous (taken for 1 to 6 months) May 5, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Bipolar Disorder: "Best med I've been on for Bipolar I. After 10 years on Lamictal as monotherapy, with continued mania and depression. I was hospitalized and switched to Depakote. I'm sad my doctors didn't try getting rid of the Lamictal sooner. I take 500mg (delayed-release) twice a day and, along with 80mg of Latuda, I haven't felt this stable or anxiety-free since I can remember. I'm not dulled out, back to my normal, serene self. Depakote is known to work wonders for mania, and I can attest to this effect being noticeable right away. I have gained a few pounds but I'm too happy with how calm, collected, and lucid I feel to think about letting Depakote go. No other side effects, and I don't find it highly sedating -- guess I'm one of the lucky ones."

   
10

FuckLamictal (taken for 1 to 6 months) April 15, 2017

18 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Migraine Prevention: "Has no effect on my migraines whatsoever. In fact they are more intense and make me more sick to my stomach. I suffer from diarrhea almost every night. I am basically bedridden."

   
1.0

Shirl2159 March 26, 2017

1 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Migraine Prevention: "I meet with a neurologist for my migraines. He put me on depakote at bedtime. I've been on it almost 6 months now and I am starting to have them as frequent as I used to...3 times a week. I also take Keppra and duloxetine every morning. I've been struggling for almost 20 years now. I just can't get rid of one all the way. Any hospital visit that I go to, they give me benadryl and tramadol, even when I tell them it doesn't work for me. I've only gone to the hospital about 6 times in my life for them."

   
2.0

dLynR_88 (taken for 1 to 6 months) March 26, 2017

4 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Bipolar Disorder: "Depakote was a nightmare. Besides having acute, non-stop stomach pain with chronic diahrrea, my hair started falling out in clumps. Good thing I have thick hair or I could have been bald at the end of this drug. I don't recommend this to anyone. It was like taking poison."

   
1.0

Velveteen Rabbit (taken for 1 to 6 months) March 1, 2017

9 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Migraine Prevention: "Depakote was started three months ago when we exhausted all efforts with every other preventive med for migraines and headaches . I have been Experiencing these my entire life. Since 6 years old . Now 35., imitrex was used to try to knock off the migraine but insurance only provides nine pills a month so I found myself breaking them just to get through a day .And if over used they will no longer work. So I'm adding in aspirin all that junk. Ending up in ER. Just to go back the next two days because the stubborn migraine would come back , or laying in bed holding my head with ice. needless to say , on a small dose 250 a day . Wow few headaches a week I can deal with. Weight gain well now I can workout no real excuse there."

   
8.0

Ljtb123 March 1, 2017

3 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Migraine Prevention: "50 Year old male, 6'5" 210 lbs, I have had migraines for ten plus years. I am on 100mgs of Topamax twice a day which gave me four to five migraine a month. Doctor put me on 250mgs Depakote and so far I am down to one migraine a month with no side effects from the Depakote - that I can tell. I call that a win!"

   
9.0

VADiesel February 22, 2017

6 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "Only my depressions cause me problems, for which Epival (Divalproex Sodium) was entirely useless, even after a few months. Lithium and especially Lamotrigine proved much better options for me."

   
1.0

Canada345 (taken for 1 to 6 months) February 19, 2017

0 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "I have struggled silently with impulses to self-destruct/self-injure for many years. Various things would trigger episodes, frustrating conversations. Some temptations were very strong, and sometimes I quickly self-injured. I let people think I was suicidal, and therapists were geared to interpret that way, but it wasn't that; it was overwhelming impulses to hurt myself, which I couldn't explain and felt humiliated about. Then I got to a very good psychiatrist, who put me on Divalproex extended-release pills, which I take at night. While I am groggy in the morning, and feel tired in the afternoon, and sometimes require a nap. Recently, I've been triggered, but the impulse to hurt myself was much less. The drug was to slow things down."

   
8.0

Secret struggler February 19, 2017

3 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "The generic Depakote immediately and effectively controlled my mania, and smoothed out my moods. In combination, I take two anti-depressants, Wellbutrin and Lexapro (both generic). This 3-prong regimen is very effective for me in controlling my bipolar disporder."

   
9.0

Tektonik66 (taken for 1 to 2 years) January 18, 2017

6 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "I just took my first dose & am hopeful yet apprehensive. Hoping to see what others are experiencing."

   
6.0

Neu (taken for less than 1 month) January 12, 2017

3 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Depakote (divalproex sodium) for Bipolar Disorder: "I have been through so many medications it's ridiculous... most of them didn't work AND caused severe side effects. The last one I was on before Depakote was lamotrigine (which really is better for bipolar II, from what I understand). I tend to run very manic (and don't have a thyroid anymore - cancer), so my doc and I decided this would probably be my best option. None of the new drugs worked on me. Depakote has been amazing. I can think a lot more clearly and I'm still me - just a lot more toned down. I've had no negative side effects except a slight tremor, but I'm also on xanax for severe anxiety, so its only noticeable when it's time for that. No weight gain, either. In fact, my appetite decreased. I haven't gained or lost, really."

   
10

espresso_dreams (taken for 1 to 2 years) December 27, 2016

42 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

For Bipolar Disorder: "It has worked well for me I was taking I can't even remember what that made me sleepy all the time and I did feel like a zombie. My doctor kept Zolof 100mg along with Depakote 500mg due to my panic attacks. After about a year we tried taking Zolof off but Depakote alone did not work for me. The combination did help my life a lot, more focused, I feel like I can organize my thoughts, get things done, follow through on plans... it changed my life for the better. The constant hunger and putting on weigh are a sadly too true for me, but given the improvement in the quality of life it gave me I find it a small price to pay. Also now that I am more focused I find it easier to actually get to the gym to work on loosing those 14 pounds."

   
8.0

hypomania (taken for 1 to 2 years) December 21, 2016

3 users found this comment helpful.

Did you?  Yes  No  |  Report inappropriate

Page 1 2 3 4 5 6 7 8 9 10 11 12 13 Next
Hide