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User Reviews for Divalproex sodium

Also known as: Depakote, Depakote ER, Depakote Sprinkles

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Divalproex sodium.

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Condition Avg. Ratings Reviews Compare
Hyperekplexia
10
   
1 review 8 medications
Borderline Personality Disorder
9.0
   
1 review 0 medications
Mania
7.8
   
23 reviews 15 medications
Epilepsy
7.1
   
56 reviews 41 medications
Bipolar Disorder
6.4
   
168 reviews 30 medications
Migraine Prevention
6.2
   
61 reviews 29 medications
Summary of Divalproex sodium reviews 7.8 310 reviews

Reviews for Divalproex sodium

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Depakote (divalproex sodium) for Bipolar Disorder: "Hi I've recently got married to my partner of 6 yrs, last year he was diagnosed with bipolar he has tried all different kinds of medicine but he’s started a new one call Depakote 5-10-17 for the last 2 weeks he’s had 2 personalities Mr Nice and Mr Horrible it can changed within mins do you think I should contact his doctor or bear with it. He’s never been like this I can’t talk to him, I can’t even look at him without him asking me what my problem is. This is really out of character. He is normal downer I know when they are coming and I can take time out and after 3-4 he’s back to him normal happy self but this I not sure how much more I can cope with!! We have a 5 yr old who keeps saying will daddy get better! I’m just in desperate need for some."

Life15hard (taken for less than 1 month) October 14, 2017

4 users found this comment helpful.
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Depakote ER (divalproex sodium) for Bipolar Disorder: "I take non generic Depakote ER 1750 mg?? Haldol 4 mg, and propranolol 20 mg. I have some hair loss, insomnia, and shakiness. I believe the medicine is finally working after 17 years of trying every bipolar medication with Depakote ER. I lose my patience and get angry at customer service representatives sometimes. I lose my patience and get mildly angry at my husband but it appears to be under control. The insomnia at times gets really bad and I wind up calling lifenet to cope. I will be trying melatonin 3mg to see if this helps. I want to try 1500 mg of Depakote ER to see if my insomnia improves also."

   
7.0

chew chew (taken for 10 years or more) October 14, 2017

1 users found this comment helpful.
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Depakote (divalproex sodium) for Bipolar Disorder: "It made my bi polar disorder worse, I had bad ringing in my ears also my heart rate increased. But it wasn't worse then when my hallucinations got so much worse then they already are."

   
9.0

Babi Girl95 October 2, 2017

5 users found this comment helpful.
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For Bipolar Disorder: "Was prescribed for moderate to severe depression and anxiety. Was never put on mood stabilizers before was never diagnosed or had bipolar or manic disorders. It was a new doc so I thought it was a new approach and went along with it. After lithium threw me deeper into my depression my doc tried the depakote. It definitely helped bring me out of my lithium fog but after 4 to 6 months I gained 10 lb and found myself in and out of depression. I ultimately had to leave this doc as he didn't want to try anything else and recommended ECT! That was hard to hear and he was completely blowing me off. I also had tried to reach out to my therapist someone I was seeing 2x a week for 8 months and she never got back to me. I'm now on an antidepressant and waiting..."

   
2.0

Jilld1314 (taken for 1 to 6 months) October 1, 2017

1 users found this comment helpful.
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For Bipolar Disorder: "I can't rate it yet but I gave it a 5 because it's been about 5 days. I've noticed a calm relax feeling. Normally after I exercise, I still have energy. Since I've started to take it, I've noticed a good calm relax tired feeling. Not a drowsy tired, which is good. Also, I'm noticing an attitude switch for the good. As for weight gain, nothing yet and I hope it stays that way. I'm eating much better and exercising more to balance just in case. I definitely feel a change for the good. Hopefully this is a fix until I can do it off medicine. If not, it is what it is. I'll keep an open mind. Let me know if anyone has anything different."

   
5.0

Joseph Robinson Jr September 18, 2017

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For Migraine Prevention: "I've been getting migraines since I hit 30 and they just kept getting worse each year. My neurologist had my on several drugs that seemed to work for a time before they stopped working. Finally I was put on Depakote 2 months ago and it's been fantastic! In just over 8 weeks I've only had a single migraine when normally I'd have 3-5 a week and so far I don't seem to be suffering from any side effects. I can finally work and have an actual social life again!"

   
10

Adam J (taken for 1 to 6 months) September 4, 2017

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Depakote (divalproex sodium) for Bipolar Disorder: "Love this medication, after 2-3 years of severe long lasting manic episodes finally decided to take meds full time. Hardly any side effects, very hungry, simply eat normally and you wont put weight on, the medication doesn't make you fat, eating does. Occasionally very tired and my stomach from time to time gets a little funny, just take with lots of water and food. Very calm, can concentrate, no racing thoughts, level, basically gave me my life back, works well at 750 even though I'm 80kgs, Dr upped me to 1000mg but felt too sedated so dropped back down. I move to 1000mg if I feel like I'm starting to drift a little for a few weeks then move back. However, this is the 7th med I have tried, all others have failed, never write one med off"

   
9.0

qwertyazsxdc (taken for 5 to 10 years) August 26, 2017

9 users found this comment helpful.
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Depakote ER (divalproex sodium) for Bipolar Disorder: "I started Depakote ER 2000mg at bedtime about a year ago after decades of ineffective treatment for depression and anxiety. Depakote proved that I was misdiagnosed: it quickly alleviated my psych. symptoms and allowed me to reduce Xanax XR dose by half and eliminate PRN Xanax. I haven't experienced the weight loss side effect, but did lose a lot of hair at first. The hair seems to be thickening up now. I would give it 10 stars except for the hair loss."

   
9.0

LAGuy (taken for 1 to 2 years) August 14, 2017

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For Migraine Prevention: "I have been experiencing migraine from my teens. It has peaked in the middle age. After retirement it has again started viciously, the neurologist said it is because of pill pooping out. Tried propronolol, topiramate etc etc and even tried valproatete. Finally I tried divalporex ER 500 within days the migraine episodes came down and migraine if any does not progress into throbbing episodes requiring triptans. Gladly it goes away like a normal headache."

   
8.0

Partha vu2GPS (taken for 1 to 6 months) August 9, 2017

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Depakote (divalproex sodium) for Epilepsy: "I used to have a wonderful smart son. About 12 years ago, I noticed changes starting to take affect in his life. He was becoming agitated, he was loosing his memory, he had no energy. I was told this was due to his having so many seizures. I just this week, after having a really bad week a few weeks ago, the doctor decided to take him off of this medication in a hospital controlled setting. After one day of not taking this medication, I am starting to see the personality of my son come back. He had gotten to the point that he made terrible decisions, he was depressed often, he was confused and was loosing his memory and his ability to talk and remember words. I'm sorry, but the benefits of controlling seizures was not worth this."

   
2.0

J A J July 24, 2017

5 users found this comment helpful.
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Depakote (divalproex sodium) for Migraine Prevention: "Horrible! I was on it for a month, and quit immediately. I have migraine with aura. My neurologist told me a secret behind closed doors cause he was a cool dude. He said get off all the crap and once the aura comes chug two beers and it will disappear no aura no headache. He swore by it and so do I."

   
1.0

Craigsugarhill (taken for 1 to 6 months) July 14, 2017

1 users found this comment helpful.
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Depakote (divalproex sodium) for Epilepsy: "Have taken this med for 28+ years with no seizures during this time. I have experienced no side effects except that my hair has become very curly. Lots of compliments! No down side. I am seizure free. No other med has worked for me."

   
10

Heroncrest July 14, 2017

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For Epilepsy: "My husband took this for a week and he turned into a unmotivated, angry, heart palpitating, paranoid Zombie. He had no relief for his headache and had tremors so bad he could not hold a fork to eat. Stomach pain, loss of appetite, hair falling out and left arm pain, to name a few more...I don't know why any doctor would order this for brain tumor pain. It is just awful. This drug may work for others but for pain it's useless..."

   
1.0

Anonymous (taken for less than 1 month) May 30, 2017

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For Bipolar Disorder: "So weird everyone complains of weight gain. This drug (divaproex sodium) makes me lose weight to the point it's actually a bit alarming. Appetite completely gone. I've stopped and started 3-5 times as I never take anything more than a year without stopping. Every time I take it like this week for example I started at 151 pounds 5"7 female. I don't work out or exercise ever and have dropped 12 pounds in 3 days. It actually usually gets so bad I have to go talk to my doctor about my weight loss. I can stomach food but it comes out in liquid form within 15 mins and clears my system. This drug is a major weight loss drug from me. I know everytime I start it it's a given I will be losing 10 pounds minimum. Good for mood."

Anonymous (taken for less than 1 month) May 19, 2017

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For Bipolar Disorder: "After two valiant attempts to get past the adverse effects, I'm finished with Depakote. The first attempt lasted a week; as it can exaggerate the effects of other meds, I became so drowsy I couldn't drive. For the second attempt, it wasn't combined with any other medication and lasted 3 weeks. I felt continually agitated and anxious, began to quickly gain weight, had terrible gas and was going to the bathroom 4-5 times a day. Additionally, my hair began to fall out so quickly, even my husband noticed (and he's NOT very observant!). The most disturbing symptom was the frequent presence of pronounced, irregular heart beats and at least one near-syncopal episode. All this in just 21 days- thanks but no thanks!"

   
2.0

Undun (taken for less than 1 month) May 12, 2017

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Depakote (divalproex sodium) for Migraine Prevention: "If you want to sleep a lot, as in all day long and gain lots of weight, enjoy. I am listless, and have pre-diabetes now. "

   
3.0

depabie (taken for 1 to 2 years) May 6, 2017

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For Borderline Personality Disorder: "It helps with the intense mood swings, negative emotions are less severe. On an 800mg a day dose, half in the morning, half at night."

   
9.0

Anonymous (taken for 1 to 6 months) May 5, 2017

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Depakote (divalproex sodium) for Bipolar Disorder: "Best med I've been on for Bipolar I. After 10 years on Lamictal as monotherapy, with continued mania and depression. I was hospitalized and switched to Depakote. I'm sad my doctors didn't try getting rid of the Lamictal sooner. I take 500mg (delayed-release) twice a day and, along with 80mg of Latuda, I haven't felt this stable or anxiety-free since I can remember. I'm not dulled out, back to my normal, serene self. Depakote is known to work wonders for mania, and I can attest to this effect being noticeable right away. I have gained a few pounds but I'm too happy with how calm, collected, and lucid I feel to think about letting Depakote go. No other side effects, and I don't find it highly sedating -- guess I'm one of the lucky ones."

   
10

FuckLamictal (taken for 1 to 6 months) April 15, 2017

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For Migraine Prevention: "Has no effect on my migraines whatsoever. In fact they are more intense and make me more sick to my stomach. I suffer from diarrhea almost every night. I am basically bedridden."

   
1.0

Shirl2159 March 26, 2017

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Depakote (divalproex sodium) for Migraine Prevention: "I meet with a neurologist for my migraines. He put me on depakote at bedtime. I've been on it almost 6 months now and I am starting to have them as frequent as I used to...3 times a week. I also take Keppra and duloxetine every morning. I've been struggling for almost 20 years now. I just can't get rid of one all the way. Any hospital visit that I go to, they give me benadryl and tramadol, even when I tell them it doesn't work for me. I've only gone to the hospital about 6 times in my life for them."

   
2.0

dLynR_88 (taken for 1 to 6 months) March 26, 2017

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Depakote (divalproex sodium) for Bipolar Disorder: "Depakote was a nightmare. Besides having acute, non-stop stomach pain with chronic diahrrea, my hair started falling out in clumps. Good thing I have thick hair or I could have been bald at the end of this drug. I don't recommend this to anyone. It was like taking poison."

   
1.0

Velveteen Rabbit (taken for 1 to 6 months) March 1, 2017

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Depakote (divalproex sodium) for Migraine Prevention: "Depakote was started three months ago when we exhausted all efforts with every other preventive med for migraines and headaches . I have been Experiencing these my entire life. Since 6 years old . Now 35., imitrex was used to try to knock off the migraine but insurance only provides nine pills a month so I found myself breaking them just to get through a day .And if over used they will no longer work. So I'm adding in aspirin all that junk. Ending up in ER. Just to go back the next two days because the stubborn migraine would come back , or laying in bed holding my head with ice. needless to say , on a small dose 250 a day . Wow few headaches a week I can deal with. Weight gain well now I can workout no real excuse there."

   
8.0

Ljtb123 March 1, 2017

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Depakote (divalproex sodium) for Migraine Prevention: "50 Year old male, 6'5" 210 lbs, I have had migraines for ten plus years. I am on 100mgs of Topamax twice a day which gave me four to five migraine a month. Doctor put me on 250mgs Depakote and so far I am down to one migraine a month with no side effects from the Depakote - that I can tell. I call that a win!"

   
9.0

VADiesel February 22, 2017

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For Bipolar Disorder: "Only my depressions cause me problems, for which Epival (Divalproex Sodium) was entirely useless, even after a few months. Lithium and especially Lamotrigine proved much better options for me."

   
1.0

Canada345 (taken for 1 to 6 months) February 19, 2017

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For Bipolar Disorder: "I have struggled silently with impulses to self-destruct/self-injure for many years. Various things would trigger episodes, frustrating conversations. Some temptations were very strong, and sometimes I quickly self-injured. I let people think I was suicidal, and therapists were geared to interpret that way, but it wasn't that; it was overwhelming impulses to hurt myself, which I couldn't explain and felt humiliated about. Then I got to a very good psychiatrist, who put me on Divalproex extended-release pills, which I take at night. While I am groggy in the morning, and feel tired in the afternoon, and sometimes require a nap. Recently, I've been triggered, but the impulse to hurt myself was much less. The drug was to slow things down."

   
8.0

Secret struggler February 19, 2017

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