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User Reviews for Divalproex sodium

Also known as: Depakote, Depakote ER, Depakote Sprinkles

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Divalproex sodium.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Hyperekplexia 1 reviews 8 medications
   
10
Mania 23 reviews 14 medications
   
7.8
Epilepsy 51 reviews 39 medications
   
7.4
Bipolar Disorder 145 reviews 33 medications
   
6.5
Migraine Prevention 53 reviews 30 medications
   
6.4
Summary of Divalproex sodium reviews 273 reviews 7.6

Reviews for Divalproex sodium

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For Bipolar Disorder: "While new to depakote, I'm not really sure this med is helping my bipolar disorder. I was on lithium er for five years and life was good, no night terrors, no mania, low level depression events at times and I was nice or cordial with people but tremors got so bad couldn't do much of anything With the depakote the night terrors are horrific at best, think I'm rapid cycling, mania appears out of the blue and depression I don't want to think about. Is it the dosage or that I'm new to depakote. Any insight appreciated"

   
4.0

Zoey's mom September 16, 2016

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For Epilepsy: "My 10 year old daughter has had seizures for 2 1/2 years. She has had about 100 petit Mal seizures a day. She has been on two other medicines that didn't help. She started taking this medicine and her seizures are down to 1-2 a day. Love this medicine for her!!!"

   
10

IzzyGirl10 September 15, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "I have Bipolar 1 rapid cycling and life was hell. Manic episodes were a little intense but the depression is what really killed me. It got worse and worse over time to the point I felt numb to the world. Life sucked and I wanted out. After taking many medications that didn't work (Abilify and Lithium to name a few) so I ended up in a mental hospital where they finally gave me Depakote. It literally SAVED MY LIFE!! I feel normal and stable for the first time in my life and I couldn't be happier. Im enjoying every second of my life now. God bless this drug (:"

   
10

SplashMaster6 (taken for 6 months to 1 year) September 15, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "I was suffering from bipolar for 10 months. After taking many medicines i was on divalproex 500 mg for 3 years and lamotrigine 150mg for 2 years. I was able to handle stress and forget that i have any depression. My dosage for both was kept to lowest 250 mg for divalproex and 50 mg for lamotrigine. But on this stage after having stress my symptoms reuccured but was not severe as before. I will have too increase the dose again."

   
10

Huzaiff (taken for 2 to 5 years) September 5, 2016

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Depakote (divalproex sodium) for Migraine Prevention: "I had debilitating migraines for 15 years and went on a small dose of Depakote (125 mg) twenty years ago. It was amazing. Maybe five headaches over all those years. However I have now gone off hormones and having steady weight gain, increased dizziness and some depression. I am uncertain what to do. Our chemistry changes as we age, and the science is not keeping up."

   
10

Meadow kat September 4, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "I have major bi-polar disorder as well as severe depression and PTSD. This med (along with Seroquel and Wellbutrin) has been a literal lifesaver. For the first time in my life my moods are stable as well as manageable."

   
10

TLGeer September 1, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "Was on this drug for about four years with Wellbutrin. The combination worked well for the first three years; however developed severe tremors and other side effects."

   
4.0

PostmodenistCupie (taken for 2 to 5 years) August 19, 2016

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For Mania: "This drug really helped me! I noticed a huge difference almost immediately and so did others around me. It helped me put down the bottle and focus on daily tasks along with not freaking out on other drivers with road rage as I previously would do. I would definitely recommend trying it, at least. As far as the weight gain aspect, that's kind of in my favor because it was always hard for me to keep weight on/gain weight. So I'm happy to gain some weight. I gained about 10 lbs in a week or two. That being said, it has become a chore to constantly be eating & only eating healthy foods due to my extremely high triglycerides (genetic)."

   
8.0

Anonymous1234282882 August 18, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "Depikote was prescribed to me after 2 manic episodes. I've been on a lot of bipolar meds so many that have made me so depressed I spent a whole summer in bed. Depikote def saved my life. It's been a year now a little anxiety but not nearly as much as I've had in the past and a little weight gain and tiredness. But no mania and very little to no depression so thankyou depikote I rate u a 10 it's been a year and no mania :) ur a life saver I take 1500 mg though to so that might be y I'm so tired"

   
10

46j1592i August 18, 2016

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Depakote (divalproex sodium) for Epilepsy: "I have nothing good to say about this drug, zero. After doing some reading, it said that depakote normally is recommended in doses up to 1000 mg a day. I was taking 3000 mg a day for 20 years. My whole life was turned upside down by it. It affected my life in so many ways. First of all, at the dose I was taking, it had so many negative side effects, it was amazing I made it through college and graduated. The side effects at the dose I was taking were very severe. The side effects were depression, weight gain, foot drop, stuttering, tremor, and kept you in a constant haze. I had all these exponentially worse than people who take smaller doses. This was the worst drug imaginable and should be banned by the FDA."

   
1.0

Shan 22 July 21, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "After my first manic episode at 39, was hospitalized and chose Depakote over Risperdal due to weight gain fears. It's been 2 weeks and along with intensive therapy and healthy lifestyle it's definitely brought me back to reality"

   
7.0

Bipolar 1 recently diagnosed (taken for less than 1 month) July 19, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "2007 - Put on 750 mg/day of Depakote alongside Lithium 800 mg/day. Killed libido stone dead. Did not help stabilise mood but worked away destabilising good lithium effect. Found this out after stopping Depakote 2014. Depakote has caused prostate cancer which was removed by radical prostatectomy June 2014. So it has caused me to be severely incontinent now, with erectile dysfunction. This month June 2016 it has been confirmed I have Multiple Myeloma a blood cancer. Depakote is the suspected trigger again. These effects result from being put on Depakote for seven years with no investigation of physical symptoms being reported to "psychiatric professionals""

   
1.0

Sion (taken for 5 to 10 years) July 12, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "I took my first dose of Depakote at night before bed. The next day I was so leveled out; I wasn't talking fast it was great. The rest of the day starting around 1:00 p.m. I slept all day. I woke up at 12:00 a.m. with my eyes extremely wide and dilated, my skin on my arms and legs was swirling (like the Starry Night painting), the walls were moving and things on the wall were levitating up and down. I was up until 3:00 a.m. and an on call nurse told me to sleep so it would wear off; I have never taken this medication again. (Taken for Schizoaffective Disorder, Bipolar type)"

   
3.0

TamaraAngel (taken for less than 1 month) July 11, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "I started taking Divalproex(Depakote)250mg on June 10th and than on June 17th I was admitted into a psychiatric hospital because of my bipolar. I learned from the psychiatrist there that the dosage I was on was absolutely nothing and would have no effect on me. The psychiatrist ended up raising the dose to 750mg. I definetly can tell that my mood is leveled out for the most part. I would recommended this to people with bipolar and people with seizures(I was diagnosed a few years ago with non eptiletic seizures). So far I dont see any side effects, thank God. I take this medication at night along with: Aripiprazole(Abilify)15mg Trazodone(Desyrel)50mg Hydroxyzine(Vistaril)50mg Clonazepam(Klonopin)1mg"

   
8.0

StayStrongJustBreath92 (taken for less than 1 month) June 25, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "Depakote put about 60 pounds on me. It did nothing for my mood accept make me a zombie. I sat around and did nothing. I had no energy, my skin itched non-stop, I developed migraine headaches and felt plain shitty all over. My muscles ached, stomach/abdomen hurt. I complained about it and my doctor upped the dose and I was on 2000 mg xr when I could not stand it any longer. I took myself off of it and have changed doctors. I hope this one will listen to what I say."

   
1.0

info2pondergmail.com (taken for 1 to 2 years) June 22, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "I was treated for clinical depression from age 18-40 using a variety of medications. I've also struggled with alcoholism, drug and sex addiction most of my adult life. I had a period of six years' solid sobriety beginning in the mid 90's but, even sober, battled with diagnosed clinical depression. At that time I was being treated with Serzone. The more the doctor increased the dosage the more depressed I would become. I obsessed on failed relationships, acted out sexually and financially in very risky ways. I finally changed Psychiatrists at the suggestion of my Therapist. The new doctor analyzed my symptoms and indicated that I had been misdiagnosed with clinical depression. His prognosis was Bipolar II Disorder accompanied by acute depression"

   
5.0

NunyaSAT (taken for 10 years or more) May 30, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "I've been taking this for a few years and I have severe headaches often along with suffering with low back pain which is constant on my left side and nothing is soothing it. Laying down is excruciating and I'm in the process of running test. This started about 4 months ago and I have been trying to deal with it and hope that it would eventually go away. It's becoming unbearable."

   
4.0

Langelle23 (taken for 2 to 5 years) May 19, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "Noticed that depakote improved stability of mood and reduced depression. However, it did not help with mania mood swings. This drug also totally removed my libido. I have never experienced such an inability for sexual activity than while taking this drug. A week after stopping the drug and sexual libido is back. I would avoid this drug if male."

   
4.0

Manuel231 May 15, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "Depakote has worked great for me. It totally helps with mania. The only medication that clears up my head and makes me feel normal. Also it gets rid of my migranes. The only bad thing is a few side effects. I gained weight and my hair fell out. And I was pretty lathargic at first. Takes a while but once it kicks in I felt like a whole person. I was off of it for a long time and recently was put back on it so going through side effects again but felt a difference rite away."

   
9.0

jamel102065 (taken for less than 1 month) May 13, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "Honestly this medicine has saved my life! I went from having multiple long lasting episodes of mania to none. Ya i still get the thoughts but im relaxed and able to make conscious choices now that im on it. The only negative side affect is the hair loss but its temporary, but so worth it. Nothing is better than feeling like you are in control of yourself, and this medicine does this for you dont be scared to ask your doctor about it!"

   
10

Susyg (taken for 6 months to 1 year) April 27, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "Really intense side effects. Weight gain, zombie like behavior, etc."

   
1.0

rxqp89 (taken for 1 to 6 months) April 22, 2016

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Depakote (divalproex sodium) for Bipolar Disorder: "I took Depakote 500mg for a week then increased my dose to 1000mg after the next week. The next day I began having terrible stomach pains and pains in my kidneys, especially after eating. I emailed my doctor and he told me the side effects would subside but they didn't. They actually got worse and the abdominal pain would linger all day and night. I also had a hard time sleeping, I would wake up every 1-2 hours and sleep less than 6 hours a night, along with having very vivid dreams. The dreams later got more and more violent/terrifying and I began to fall into a very deep depression, one I had never felt in my entire life. I stopped taking this medication after three weeks. I will never take this medication even if it saved my life."

   
1.0

Bipolar2 April 2, 2016

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Depakote ER (divalproex sodium) for Bipolar Disorder: "Have been taking this med since 1992 w/ some breaks here and there. I too have been on, what would seem, every med for Bipolar diagnosis. I take 1750mg and also take 400mg of Lamictal (another mood stabilizer which seems to help with the depression) My only issue had been weight gain which remains a problem. 10 years stable, after being hospitalized for 8 months due to manic episode and psychotic break (was only taking Topamax at that time). Would highly recommend."

   
9.0

blessed5# March 11, 2016

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Depakote (divalproex sodium) for Migraine Prevention: "Started having migraines about ten years ago. The only treatment that has ever worked for me is Depakote. Everybody is different, but for me this was a Godsend. Nothing worked and Topomax was only a temporary solution. The thing is that after a two month regiment my headaches completely went away. I stopped taking the medication for two or three years before my migraines returned. I went on another regiment and again I went several years without a headache. Yes, I did have slight weight gain, and yes it did affect my ability to perform sexually, but I did not have to continue taking it for more than 3 months. Cysticercosis as a child and a catalyst of factors cause my headaches. Depakote works."

   
10

Manny05 March 10, 2016

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Depakote (divalproex sodium) for Epilepsy: "This medicine took 3 weeks to fully kick in. I had the side effect of increased appetite, but I haven't gained any weight because I eat a low carb diet and workout 4 times a week. I do not have any side effects anymore and this mostly controls my temporal lobe epilepsy."

   
10

Anonymous (taken for 1 to 6 months) February 28, 2016

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