Skip to Content

Medications for Borderline Personality Disorder

Other names: BPD; EID; EIRD; Emotion-Impulse Regulation Disorder; Emotional Dysregulation Disorder; Emotional Intensity Disorder; Emotional Regulation Disorder; Emotionally Unstable Personality Disorder; ERD; EUPD; Impulsive Personality Disorder; IPD; Personality Disorder, Borderline

About Borderline Personality Disorder:  Borderline personality disorder (BPD) is a serious mental illness characterized by pervasive instability in moods, interpersonal relationships, self-image, and behavior.

Drugs Used to Treat Borderline Personality Disorder

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
quetiapine Off Label C N X 74 reviews
7.0

Generic name: quetiapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

lamotrigine Off Label C N X 31 reviews
7.0

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

lithium Off Label D N X 4 reviews
4.0

Generic name: lithium systemic

Drug class: miscellaneous antipsychotic agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

risperidone Off Label C N X 15 reviews
5.0

Generic name: risperidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

olanzapine Off Label C N X 22 reviews
7.0

Generic name: olanzapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

fluoxetine Off Label C N X 5 reviews
9.0

Generic name: fluoxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

clonazepam Off Label D 4 X 4 reviews
8.0

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

aripiprazole Off Label C N X 17 reviews
7.0

Generic name: aripiprazole systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

sertraline Off Label C N X 9 reviews
6.0

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

diazepam Off Label D 4 X 3 reviews
7.0

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

lorazepam Off Label D 4 X 2 reviews
9.0

Generic name: lorazepam systemic

Drug class: benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

clozapine Off Label B N X 3 reviews
7.0

Generic name: clozapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

buspirone Off Label B N X 3 reviews
4.0

Generic name: buspirone systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

topiramate Off Label D N X 7 reviews
7.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

alprazolam Off Label D 4 X 1 review
5.0

Generic name: alprazolam systemic

Drug class: benzodiazepines

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

escitalopram Off Label C N X 3 reviews
8.0

Generic name: escitalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

divalproex sodium Off Label D N X 2 reviews
8.0

Generic name: divalproex sodium systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions,

For professionals: Prescribing Information

Off Label: Yes

oxcarbazepine Off Label C N X 3 reviews
8.0

Generic name: oxcarbazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

citalopram Off Label C N X 2 reviews
4.0

Generic name: citalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

haloperidol Off Label C N X 1 review
7.0

Generic name: haloperidol systemic

Drug class: miscellaneous antipsychotic agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

l-methylfolate Off Label N N 2 reviews
6.0

Generic name: l-methylfolate systemic

Drug class: vitamins

For consumers: dosage,

For professionals: A-Z Drug Facts

Off Label: Yes

lurasidone Off Label B N X 8 reviews
8.0

Generic name: lurasidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

carbamazepine Off Label D N X 2 reviews
5.0

Generic name: carbamazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

asenapine Off Label C N X 2 reviews
8.0

Generic name: asenapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

paliperidone Off Label C N X Add review Rate

Generic name: paliperidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Learn more about Borderline Personality Disorder

Micromedex® Care Notes

Symptoms and treatments

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Browse Drugs by Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide