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User Reviews for Cyclobenzaprine

Also known as: Amrix Comfort Pac with Cyclobenzaprine

Cyclobenzaprine has an average rating of 6.0 out of 10 from a total of 558 ratings on Drugs.com. 47% of reviewers reported a positive experience, while 30% reported a negative experience.

Condition Avg. Rating Reviews Compare
Muscle Spasm  
5.6
360 reviews 50 medications
Sciatica  
5.9
69 reviews 282 medications
Fibromyalgia  Off-label
7.8
55 reviews 21 medications
Migraine  Off-label
7.7
42 reviews 88 medications
Chronic Myofascial Pain  Off-label
4.8
16 reviews 42 medications
Temporomandibular Joint Disorder  Off-label
6.2
16 reviews 31 medications
Summary of Cyclobenzaprine reviews 6.0 558 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Cyclobenzaprine

K · Taken for less than 1 month · February 26, 2020

Flexeril (cyclobenzaprine) for Muscle Spasm: “I took this briefly for pelvic pain and muscle spasm. I would never wish to scare anyone with side effect horror stories, but I strongly urge anyone taking this drug to pay attention to how they feel emotionally while on it. After just a few days of taking this drug, I felt highly irritable and was in the darkest of places in my mind. I was taking Tramadol at the same time so I thought maybe it was a combination of the two. I stopped the tramadol for several days and just took the flexeril, but I still felt unmotivated, depressed, and angry. I decided it was not worth it even if it offered physical relief. My advice is always do your research before starting a new medication. Many doctors don’t discuss these side effects with patients and depending on what you’re taking, you may unwittingly be on a dangerous combination of drugs that can affect you not just physically, but emotionally as well.”

1 / 10
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TomB · Taken for 5 to 10 years · June 6, 2019

Flexeril (cyclobenzaprine) for Muscle Spasm: “I don't understand why so many users are started on 10 mg. I have had low back spasms due to work injury aggravated by ageing (now 67 yrs). I take one 5 mg in evening as need with acetaminophen and am able to get good relief for my problem, only occasional daytime use. I do not take every day, only as needed, seldom more than two or three consecutive days. Sometimes more is not better, lowest effective dosage is the way to go. For those complaining on 10 mg, get a pill splitter & try 5 mg.”

9 / 10
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Anonymous · May 23, 2013

Flexeril (cyclobenzaprine) for Sciatica: “I have two bulging discs L4/L5 and L3/L4 and herniated L5/S1 and pinched nerves. My hydrocodone wasn't enough, I started taking Flexeril twice a day and the pain reduced to almost nothing and the burning down my legs stopped from my pinched nerves. It doesn't last as long as I would like but it makes the day go by a lot easier and is definitely worth taking it.”

10 / 10
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fayfaith · May 11, 2014

Flexeril (cyclobenzaprine) for Muscle Spasm: “It really does work and helps me to relax so I can rest & sleep. And I've taken it for off & on for several years! I have arthritis, pinched nerves, muscle spasms & a lot more elements. IT WORKS. But what works for one might not work for another. Best wishes to everyone!”

10 / 10
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Miss · Taken for 2 to 5 years · June 4, 2020

Flexeril (cyclobenzaprine) for Sciatica: “Been Rx for this med Flexeril for years, I may take it once a month when I have a flare up from my chronic pain from Fibromyalgia . I’m also on Norco (hydrocodone) and take flexeral when needed. It takes 2 hours to start working and it knocks me out, I wake up with less pain and actually able to move in the morning before taking my pain medication. On 10mg, I cannot take it during the day, (I did in the beginning and didn’t notice much) but eventually to only at nighttime.”

8 / 10
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Working Man · Taken for 6 months to 1 year · May 16, 2014

Flexeril (cyclobenzaprine) for Muscle Spasm: “I find Flexeril 'tops' for killing muscle pain associated with spasm, knots and/or injury. Compared to Valium (which I also have) the Flexeril does a better job for the actual pain & spasm. However, Flexeril does have heavy side effects which could discourage first time users: - Dry mouth and eyes. - A 'tight feeling' of the upper chest & bronchioles (very similar to what a high dose of Benadryl does). - Slightly blurry vision. - A substantial drowsiness which, for me, occurs about 4 hours after taking the dose. It becomes a struggle to stay awake. Definitely never go above the recommended dose - because of the harsh side effects.”

9 / 10
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grateful yogi · June 10, 2017

Flexeril (cyclobenzaprine) for Muscle Spasm: “I have severe degenerative disc disease and Flexeril was one of many different medicines my G. P. tried on me, to avoid opioids, when he decided that he would not continue my Rx's given to me properly by an M. D. in pain management. I took only one pill not 2, which knocked me out. 1 did nothing. 2- I could not focus, drive, etc- I was only on Soma, Clonazapam & they are fine without Flexeril; I can concentrate, without sleepiness, just need pain medication and if someone will not prescribe, best of luck- to us all--we the injured & healing, even doing our PT ,yoga daily for me, as it indeed strengthens all muscles, especially involving the spine, are prejudiced against. Thanks FDA. We are the suffering; boo on the government, pharma companies, who will not provide relief that works.”

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Frequently asked questions

Anita · Taken for 1 to 6 months · October 3, 2018

Flexeril (cyclobenzaprine) for Muscle Spasm: “I injured my back at age 24 and have had flare ups over the years. I'm now almost 60 and back pain is almost a daily thing. Being barely able to walk, I went to my PCP to get something for it but she's a die hard no opioids or controlled substances of any kind. Instead, she gave me flexeril - 10 mg twice a day. I had never taken them before and didn't have much hope for pain relief. But, I was wrong. After taking them for a few days I felt like a different person. Now I only take as needed. I've had no side effects except for dry mouth. Not even the "loopiness" or drowsiness she had warned me about.”

8 / 10
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My aching back · Taken for less than 1 month · August 24, 2020

Flexeril (cyclobenzaprine) for Sciatica: “I have just had severe sciatica pain in my left side with pain that goes whizzing down the front of my left leg. I was given Flexeril and taking 800 mg Advil. Flexeril works slightly. I can walk well for about 2 hours. After that, it's agony every minute I'm at work. It wears off too fast. Slight short lasting relief won't get me through an 8 hour shift. Doctors don't seem to want to give out the stuff that DOES work. Such as Soma, Norco or Percocet. Torodol maybe. Tramadol maybe. Anyway. Flexeril gives 2 hours of slight relief.”

2 / 10
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Buni · Taken for 5 to 10 years · February 16, 2014

Flexeril (cyclobenzaprine): “I have had great difficulty sleeping (staying asleep) for years and years and the only thing that really works to help me get a good night sleep and also help with my fibromyalgia is Flexeril. I take 5 mg most nights and on occasion possibly 8 mg (breaking the 10 mg) and sleep like a baby with no painful muscle cramps in legs and come completely awake in the mornings with a cup of coffee. The wonderful thing about Flexeril is that it also relaxes the MIND which can keep a person awake for hours thinking and rethinking "to-do" lists as well as other anxious thoughts. I have taken it for a long time and have no adverse side effects. ”

10 / 10
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Chloe · Taken for less than 1 month · December 31, 2019

Flexeril (cyclobenzaprine) for Sciatica: “I wish I could give Flexeril a rating of zero. I was diagnosed with sciatica 2 weeks ago and was given this medication. I do my physical therapy/stretching each day, but I feel like taking this medicine is useless. It doesn't relax my muscles at all. My pain was at a 9 two weeks ago, but now it's at a 12 after all the daily stretching. I'm in agonizing pain when I sit, walk, move, and Flexeril hasn't helped me at all. I'm glad it works for some people, but for me it works less than ibuprofen.”

1 / 10
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BeeGees · Taken for less than 1 month · May 13, 2013

Flexeril (cyclobenzaprine) for Muscle Spasm: “Definitely relaxed my back muscles. The only odd side effect is a very, very, very strong hangover. I couldn't focus my eyes on one thing for more than a second. Caused me to sleep about 18 hours at a time.”

8 / 10
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Sunshine9 · February 3, 2013

Flexeril (cyclobenzaprine) for Muscle Spasm: “I get muscle tightness and spasms often after workouts as a side effect of arthritis in my back & neck (which was diagnosed for me in 2011). Flexeril was prescribed for this problem. It works great, but here is my feedback. First few times I took it, it knocked me out. Had to lay down & sleep. Took awhile of taking it in smaller doses, where this effect went away. After 3 weeks of use, I started holding fluids really bad. So I no longer use it daily, only as desperately needed. Also causes constipation, so be prepared to add Fiber to your diet to help with that. When I do take it, I'm able to work out the problem areas in my neck (which bothers me the most) with sports cream rub, while on the Flexeril. I can definitely recommend!”

9 / 10
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Tammy73 · January 10, 2015

Flexeril (cyclobenzaprine) for Fibromyalgia: “Finally! Something that actually works. I've been diagnosed with fibromyalgia almost 2 years ago now and have been on Lyrica and Cymbalta with little relief. My doctor added Flexeril 3 days ago and I am in heaven! I have not felt rested in a very long time and my pain seems to be diminished somewhat. I really feel good and have actually smiled ALL day today. I sure hope this keeps up! Yay for Flexeril!”

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Randomperson · Taken for less than 1 month · February 18, 2020

Flexeril (cyclobenzaprine) for Muscle Spasm: “I was prescribed 10mg Flexeril last week as couldn’t turn my head right or left. I also have flaring bursitis. Was told to use this for night time to help me sleep. It did nothing at all. I had to take another one a few hours later. Same thing the next night. Didn’t take out for 2 nights, then took one: didn’t notice anything at all. Today I noticed I’m extra cranky and irritated- it was extremely hard to focus on a task and get things done. Nothing got accomplished today and not I won’t sleep. Do not recommend.”

1 / 10
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Gigi · Taken for less than 1 month · January 31, 2020

Flexeril (cyclobenzaprine) for Muscle Spasm: “I am so glad I found this article of comments online about Flexeril. I was wondering if the pain from the back muscle spasms was causing me to be so agitated and short tempered until I read another comment about a woman whose mood became very nasty and mean tempered when she was on Flexeril. I’m usually very easy-going but have been an intense pain since Monday when I’ve bent over and pulled a muscle. I’ve had this occur several years ago and was able at that time to go to my primary doctor and get a shot for inflammation and some info on exercises. These helped tremendously and eventually I got back to normal. However this time My doctor was out of town and I couldn’t get anyone to get me in for an appointment so I called for a refill on my Flexeril and every since I’ve been taking it three days I have noticed I am so agitated and quick tempered with my pets I have in my home ? after reading all this I will probably wean myself off...”

5 / 10
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freednerd · Taken for 1 to 6 months · February 27, 2013

Flexeril (cyclobenzaprine) for Muscle Spasm: “Helps with muscle pain and tension. Does cause drowsiness, but if you are hurting it is worth it. Take currently for Fibromyalgia when I am having a bad day. Can take small doses and function at work, but larger doses I will be asleep.”

8 / 10
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Anonymous · August 27, 2010

Amrix (cyclobenzaprine) for Muscle Spasm: “Regarding the comment above that states Flexeril works but Amrix does not... as a pharmacist, I would like to clarify that both Flexeril and Amrix are brand names of the drug cyclobenzaprine, a muscle relaxant. Flexeril is released all at once, thus must be taken multiple times daily. Amrix is released slowly over 24 hrs, thus it is taken once daily.”

10 / 10
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HankySpanky · November 22, 2014

Flexeril (cyclobenzaprine) for Muscle Spasm: “I take 10mg 3x a day along with ibuprofen when my lower back starts acting up. I am better in 2 - 3 days. Works great for me. My doctor used to also prescribe a narcotic pain reliever but that did nothing for the pain. Ibuprofen along with Flexeril works best.”

9 / 10
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Wishing for relief · Taken for less than 1 month · January 16, 2020

Flexeril (cyclobenzaprine) for Muscle Spasm: “This medicine sucks. I took it before bedtime as I was prescribed, and didn't really notice any effects. After two or three days like that, I began taking the medicine at about 7 pm so that I could be awake to notice if the medication worked or not. At 11 pm, I still felt nothing. I didn't feel any relief from my muscles nor was I the least bit drowsy. I told my doctor my concerns about it not working and her response was "It works longterm. You'll see the results after two weeks of taking the medicine." Well, two weeks have come and I still feel the same. I'm still sore, tense and in pain.”

1 / 10
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LAD:-) · February 9, 2017

Flexeril (cyclobenzaprine) for Muscle Spasm: “It is unbelievable what a person has to go through to get pain relief. Physicians don't seem to distinguish between real and fake in spite of a patient with no history of narcotic or opiod use. I was going into two weeks of an RA flair and in between rheumatologists. Barely able to walk or use my hands that were red and swollen like sausages and unable to speak without crying, I attempted my best to explain to my doc I was having an RA flair. He prescribed Lyrica. I went to an ortho surgeon asked for cortisone hand injections. Nope. Went to podiatrist asked for cortisone injections so I could walk. He gave me one, going back in 3 days for other foot. Ended up taking 3 generic 10 mg Flexeril. Went to bed, slept all nite, woke up pain free.”

10 / 10
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sleepy001 · December 11, 2014

Flexeril (cyclobenzaprine) for Muscle Spasm: “Yikes! I don't like taking medication of any kind. I've had a frozen shoulder for 8 months and am ready to gnaw off my own arm from the pain and lack of mobility. My PCP prescribed this for shoulder impingement. I took half of a 10 at 8 pm and slept all night. I do have a very dry mouth and feel hung-over this morning. I'd reserve this for bedtime use only.”

7 / 10
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Emelyn G · Taken for less than 1 month · April 1, 2020

For Chronic Myofascial Pain: “Hello All, I was prescribed cyclobenzaprine for the first time 12 years ago after a neck injury. Made me really drowsy and helped me sleep for hours and hours. I was 20 back then so I could afford it on days I didn't have college. Now 32 with 2 small kids and some nerve damage and degenerative arthritis on one shoulder, My Dr prescribed again. Decided to give it another chance. I take 5mg tab which helps me relax my mind and face muscles (For some reason I do not relax while I sleep). I wake up a little drowsy but nothing a cup of coffee wont fix. I take right before bed and works around 15-20 mins after taking. Hope this helps anyone out there.”

9 / 10
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bamanurse195 · Taken for less than 1 month · September 22, 2020

Flexeril (cyclobenzaprine) for Muscle Spasm: “I have had severe lower back pain and back spasms for a few days and was given this Flexeril as well as told to take Advil and Tylenol. Must say it does work best with the Tylenol. Took my spasms away and I was able to catch a break from the pain.”

10 / 10
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Anonymous · Taken for less than 1 month · April 11, 2015

Flexeril (cyclobenzaprine) for Muscle Spasm: “My doctor prescribed 10 mg flexeril 3 times per day for a painful and crippling muscle spasm in my lower back. The dosage helped relax my back, but it also relaxed everything else in my body. I had difficulty controlling my extremities, as if they were detached from the rest of my body. Sometimes I didn't have enough control of my tongue to speak clearly. Sometimes I felt weak and uncoordinated, for example, I had to take my time going up and down stairs. I felt generally sleepy and spaced out most of the time, and felt thirstier than usual. I also needed more sleep than usual, 10 hours. Overall effective for helping my condition, but the side effects were a little frightening.”

8 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.