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Skeletal muscle relaxants

What are Skeletal muscle relaxants

Skeletal muscle relaxants (also simply called muscle relaxants) are a diverse group of medicines that have the ability to relax or reduce tension in muscle. Some (such as baclofen, methocarbamol, and tizanidine) work in the brain or spinal cord to block over-excited neuronal (nerve) pathways. Others (such as dantrolene and botulinum toxin) act directly on muscle. Cannabis extract is thought to have a dual effect.

Muscle relaxants treat two main conditions: spasticity (stiff, rigid muscles) caused by conditions such as cerebral palsy, multiple sclerosis, and stroke; or muscle spasms which are typically temporary and associated with conditions such as tension headache, low back pain, or fibromyalgia.

Only three muscle relaxants - baclofen, dantrolene, and tizanidine are FDA approved to treat general spasticity; however, six (carisoprodol, chlorzoxazone, cyclobenzaprine, metaxalone, methocarbamol, and orphenadrine) are approved to treat muscle spasm. Botulinum toxin is only approved to treat spasticity in certain muscle groups of the upper and lower limbs. Many other medications are also used to treat spasticity or muscle spasm although most are not approved for this indication.

Evidence supporting the effectiveness of skeletal muscle relaxants for muscle spasm is sparse; most trials are old and not of good quality. For this reason, skeletal muscle relaxants should only be used to treat muscle spasm if other treatments fail.

List of Skeletal muscle relaxants:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Dantrium (Pro, More...)
generic name: dantrolene
2 reviews
   
10
Myobloc (Pro, More...)
generic name: botulinum toxin type b
2 reviews
   
9.3
Soma (Pro, More...)
generic name: carisoprodol
149 reviews
   
8.9
Dysport (Pro, More...)
generic name: abobotulinumtoxinA
4 reviews
   
7.8
Zanaflex (Pro, More...)
generic name: tizanidine
88 reviews
   
7.7
Skelaxin (Pro, More...)
generic name: metaxalone
77 reviews
   
7.3
Amrix (Pro, More...)
generic name: cyclobenzaprine
44 reviews
   
7.2
Lioresal (Pro, More...)
generic name: baclofen
18 reviews
   
7.0
Botox (Pro, More...)
generic name: onabotulinumtoxinA
203 reviews
   
6.6
Flexeril (Pro, More...)
generic name: cyclobenzaprine
163 reviews
   
6.5
Norflex (Pro, More...)
generic name: orphenadrine
15 reviews
   
6.5
Lorzone (Pro, More...)
generic name: chlorzoxazone
20 reviews
   
6.4
Robaxin (Pro, More...)
generic name: methocarbamol
54 reviews
   
6.4
Botox Cosmetic (Pro, More...)
generic name: onabotulinumtoxinA
7 reviews
   
6.3
Parafon Forte DSC (Pro, More...)
generic name: chlorzoxazone
3 reviews
   
5.9
Fexmid (Pro, More...)
generic name: cyclobenzaprine
4 reviews
   
5.8
Gablofen (Pro, More...)
generic name: baclofen
3 reviews
   
5.8
Robaxin-750 (More...)
generic name: methocarbamol
28 reviews
   
5.6
Lioresal Intrathecal (More...)
generic name: baclofen
3 reviews
   
5.2
Xeomin (Pro, More...)
generic name: incobotulinumtoxinA
1 review
   
5.0
Comfort Pac with Cyclobenzaprine (More...)
generic name: cyclobenzaprine
2 reviews
   
4.5
Kemstro (More...)
generic name: baclofen
0 reviews
   
2.0
Antiflex (More...)
generic name: orphenadrine
0 reviewsAdd rating
Dantrium Intravenous (Pro, More...)
generic name: dantrolene
0 reviewsAdd rating
Mio-Rel (More...)
generic name: orphenadrine
0 reviewsAdd rating
Orfro (More...)
generic name: orphenadrine
0 reviewsAdd rating
Orphenate (More...)
generic name: orphenadrine
0 reviewsAdd rating
Remular-S (More...)
generic name: chlorzoxazone
0 reviewsAdd rating
Revonto (Pro, More...)
generic name: dantrolene
0 reviewsAdd rating
Ryanodex (Pro, More...)
generic name: dantrolene
0 reviewsAdd rating
Vanadom (More...)
generic name: carisoprodol
0 reviewsAdd rating
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