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Cyclobenzaprine and Confusion: What Users Say

Brand names: Amrix Comfort Pac with Cyclobenzaprine

Confusion: mentioned by 15 users (2.4%)

Based on user experiences from 618 Cyclobenzaprine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 19.9%
dry mouth 8.3%
tiredness 7.6%
sleepy 5.3%
dizziness 4.2%
hangover 2.8%
confusion 2.4%
depression 2.4%
insomnia 2.4%
brain fog 2.1%

Reviews for Cyclobenzaprine

Commonly mentioned side effects
  • Fra...
  • February 19, 2012

Cyclobenzaprine for Sciatica "This was the first time I had ever taken cyclobenzaprine. I took one (1) 10mg tablet on a Thursday evening around 6:30 pm, and all day the next day I felt slight confusion, loss of concentration, and it felt like my head was in a fog. It did not help with pain but allowed me to get some much-needed sleep."

5 / 10
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84 Report
  • Shi...
  • Taken for less than 1 month
  • May 21, 2017

Cyclobenzaprine for Muscle Spasm "My mom, who is 92 and has dementia, was prescribed Flexeril along with Tramadol for muscle pain. After 4 days of taking them, she woke up this morning totally confused and hallucinating. She had no idea where she was and was in tears. This forgetfulness was not her normal. The doctor prescribed Tramadol to be taken twice a day and the Flexeril 3 times. On the 1st day, she slept all day, and early evening sat with her head in her hand. When I'd ask how she was feeling, she looked at me dazed and said great, and then her head would drop back into her hand. The next day, I reduced the meds to once a day. She was still sleeping a lot, but this morning she was very confused and dazed! She is done with both meds. Dementia and these meds are NOT good!!!"

1 / 10
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44 Report
  • Dan...
  • July 9, 2018

Cyclobenzaprine for Muscle Spasm "I've been on Flexeril now for about 2 years. My neurologist was treating me for temporomandibular joint (TMJ) syndrome. I was okay taking 10 mg once a day. It was when he increased my dosage that I started to have very, very serious side effects. Among the normal side effects-sleepiness, grogginess, confusion-that's a given, but it was working, so I tolerated it. When I jumped to 20 mg a day, within a week or two, I started to develop much more serious side effects. I developed a rapid heart rate, and one of the most serious was I could not urinate. I was put on a catheter on Easter Sunday for about 5 weeks. Just prior to that, I was having difficulty swallowing. Along with that, I started to have hallucinations big time. I ended up with such bad nightmares that I literally fell out of my bed three nights in a row. My urologist finally put the pieces together when he found out how long I had been on Flexeril. He told me to stop immediately, and when I did, within a week or two, most of my symptoms have disappeared."

5 / 10
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32 Report

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Frequently asked questions

  • Jbi...
  • December 20, 2016

For Muscle Spasm "This stuff is brutal. Helps me sleep with all of my neck and shoulder stiffness and pain, but I'm exhausted, lethargic, dizzy, off balance, panicked, and confused for 2 days after. I can't take this anymore. I feel like I'm in purgatory when I take this stuff."

2 / 10
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28 Report
  • JM2...
  • August 23, 2011

Cyclobenzaprine for Sciatica "Taking for back pain in left lower disc. Works very well, but I must take it by 8 pm or after dinner, or I wake up very sluggish the next morning (I wake up at 8:30 am) and feel cloudy-headed for the whole morning. I only take it when the pain is really bad."

8 / 10
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35 Report

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  • Anonymous
  • July 21, 2009

For Sciatica "I notice no pain relief from this drug. It makes me extremely sleepy throughout the day and causes my mouth to stay dry. At least I get a good night's sleep, but I wake up feeling groggy and never get going after that. Sometimes causes me to feel confused, but maybe that is the groggy effect returning. I'm male, 42 years old, and in good health overall."

5 / 10
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19 Report
  • Sha...
  • July 28, 2016

For Muscle Spasm "It knocked me out for 12 hours. Didn't get rid of my pain. Made me feel confused and very irritable. I'm still feeling effects 5 days later (small waves of confusion/anxiety with nausea). I wouldn't recommend it. Rather have someone stand on my hurt back all day than to use this again."

1 / 10
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20 Report

More FAQ

  • Sha...
  • July 28, 2016

For Muscle Spasm "It knocked me out for 12 hours. Didn't get rid of my pain. Made me feel confused and very irritable. I'm still feeling effects 5 days later (small waves of confusion/anxiety with nausea). I wouldn't recommend it. Rather have someone stand on my hurt back all day than to use this again."

1 / 10
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20 Report
  • Dee...
  • July 14, 2016

For Muscle Spasm "I have tried this several times. While it works well for the muscle spasms, I can't function the next day. I am very confused and looking for something to get it out of my system. I just read it can stay in your system 5 to 10 days."

2 / 10
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12 Report
  • Jar...
  • Taken for 1 to 6 months
  • November 5, 2015

For Muscle Spasm "This worked for me! It let the tense muscles in my back relax, so I could fall asleep. I had a lot of confusion while taking the medication (like a mental fog), so I stopped taking it and now take melatonin."

6 / 10
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13 Report
  • lie...
  • Taken for 6 months to 1 year
  • March 4, 2019

Cyclobenzaprine "Almost died taking this medication. I was Amrix for anxiety (off label). I was given something that was very dangerous and without consideration to risk. I am sure this medication makes people feel good if sleep is needed, I just hope they know they will be too tired and confused to realize the truth. Just getting health back. Sick of dangerous medication."

2 / 10
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11 Report
  • Anonymous
  • November 7, 2008

Cyclobenzaprine for Sciatica "Flexeril does not really take away my pain, but it helps me relax and sleep. If you take too much, it will cause confusion."

6 / 10
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72 Report
  • Jef...
  • Taken for less than 1 month
  • October 6, 2013

Cyclobenzaprine for Muscle Spasm "I broke out in a bright red rash on my face. Was very irritable and dizzy. Was extremely hot and suffered a lot of confusion."

1 / 10
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33 Report
  • Cat...
  • July 1, 2016

For Muscle Spasm "I was extremely confused on this medication, it was awful. I am glad that my doctor diagnosed me properly, as I could easily have been mistaken for dementia."

1 / 10
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16 Report
  • Cat...
  • July 1, 2016

"I was extremely confused on this medication, it was awful. I am glad that my doctor diagnosed me properly, as I could easily have been mistaken for dementia."

1 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.