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Medications for Chronic Myofascial Pain

Other names: CMP; MPS; Myofascial Pain Syndrome; Myofascial Syndrome

What is Chronic Myofascial Pain:  Chronic myofascial pain (CMP), also known as Myofascial pain syndrome (MPS), is a syndrome characterized by chronic pain caused by multiple trigger points and fascial constrictions.

Medications to treat Chronic Myofascial Pain

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
cyclobenzaprine Off Label B N X 6 reviews
5.0

Generic name: cyclobenzaprine systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
amitriptyline C N X 3 reviews
8.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
clonazepam Off Label D 4 X 1 review
8.0

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
ibuprofen C N X Add review
5.0

Generic name: ibuprofen systemic

Brand names:  Advil, Motrin, IBU, Addaprin, Actiprofen, Motrin IB, Proprinal, A-G Profen, Haltran, NeoProfen, Nuprin, Q-Profen, Genpril, Ibu-4, Ibu-6, Ibu-8, IBU-200, Ibu-Tab

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
naproxen C N X 1 review
5.0

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Anaprox-DS, EC-Naprosyn, Flanax Pain Reliever, Aflaxen, Anaprox, All Day Pain Relief, Naprelan, All Day Relief

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Aleve C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Advil C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Motrin C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Naprosyn C N X 1 review
3.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
IBU C N X Add review
6.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Addaprin C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Actiprofen C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Anaprox-DS C N X Add review
7.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
EC-Naprosyn C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Flanax Pain Reliever C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Motrin IB C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Proprinal C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
A-G Profen C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Aflaxen C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Anaprox C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Haltran C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
NeoProfen C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Nuprin C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Q-Profen C N X Add review Rate

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
All Day Pain Relief C N X Add review Rate

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Learn more about Chronic Myofascial Pain

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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