Generic Name: baclofen (BAK loe fen)
Brand Names: Lioresal Intrathecal, Gablofen, FIRST Baclofen
Medically reviewed by Kaci Durbin, MD Last updated on Dec 29, 2018.
What is baclofen?
Baclofen is a muscle relaxer and an antispasmodic agent.
Baclofen is used to treat muscle symptoms; such as spasm, pain and stiffness; caused by multiple sclerosis, spinal cord injuries, or other spinal cord disorders. It is given intrathecally (directly into the spinal cord) or orally (by mouth).
Do not use baclofen at a time when you need muscle tone for safe balance and movement during certain activities. Do not drive or operate heavy machinery until you know how baclofen affects you.
Do not stop using baclofen suddenly, or you could have unpleasant withdrawal symptoms.
Before taking this medicine
You should not use baclofen if you are allergic to it.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
epilepsy or other seizure disorder;
Parkinson’s disease, cerebral palsy, or rheumatoid disorders;
mental disorders such as schizophrenia or bipolar disorder;
a stroke or blood clot; or
if you also use a narcotic (opioid) medication.
Using baclofen may increase your risk of developing an ovarian cyst. Talk with your doctor about your specific risk.
Baclofen has not been studied in pregnant women. Tell your doctor if you are pregnant or if you become pregnant while using this medicine.
It is not known whether baclofen passes into breast milk or if it could harm a nursing baby. Tell your doctor you are breastfeeding before using baclofen.
Baclofen is not approved for use by anyone younger than 12 years old.
How should I take baclofen?
Take baclofen exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (do no use a kitchen spoon).
Call your doctor if your muscle symptoms do not improve, or if they get worse.
Do not stop using this medicine suddenly, or you could have unpleasant withdrawal symptoms such as hallucinations or a seizure. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include muscle weakness, vomiting, drowsiness, dilated or pinpoint pupils, weak or shallow breathing, seizure, or coma.
What should I avoid while taking baclofen?
Do not use baclofen at a time when you need muscle tone for safe balance and movement during certain activities. In some situations, it may be dangerous for you to have reduced muscle tone.
Drinking alcohol with this medicine can cause side effects.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Baclofen side effects
Get emergency medical help if you have signs of an allergic reaction to baclofen: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
weak or shallow breathing;
confusion, hallucinations; or
a seizure (convulsions).
Common baclofen side effects may include:
drowsiness, dizziness, weakness, tired feeling;
sleep problems (insomnia);
nausea, constipation; or
urinating more often than usual.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect baclofen?
Taking baclofen with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death.
Tell your physician if you are taking any of the following medications:ul>
Other drugs may interact with baclofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use baclofen only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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More about baclofen
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Compare Alternatives
- Support Group
- Pricing & Coupons
- 290 Reviews
- Drug class: skeletal muscle relaxants
- FDA Alerts (3)
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- Baclofen Intrathecal Injection
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