Baclofen Alternatives Compared
Baclofen Remove Baclofen from your drug comparison | Cyclobenzaprine Remove Cyclobenzaprine from your drug comparison | Tizanidine Remove Tizanidine from your drug comparison |
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Baclofen Remove Baclofen from your drug comparison | Cyclobenzaprine Remove Cyclobenzaprine from your drug comparison | Tizanidine Remove Tizanidine from your drug comparison | ||||||||||||||||||||||||
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Baclofen relieves muscle spasm associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... View more |
Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. The dosage should be individualized and because it only lasts for a short time in the body, can be... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: drowsiness. See the full baclofen side effects document. |
See the full cyclobenzaprine side effects document. |
Commonly reported side effects include: bradycardia, dizziness, drowsiness, hypotension, asthenia, fatigue, xerostomia. See the full tizanidine side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all baclofen prices |
View all cyclobenzaprine prices |
View all tizanidine prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Gablofen, Lioresal, Lioresal Intrathecal, Ozobax | Amrix, Comfort Pac with Cyclobenzaprine, Fexmid | Zanaflex | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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6.8 hours |
72 hours |
2.5 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 347 drugs are known to interact with baclofen:
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A total of 375 drugs are known to interact with cyclobenzaprine:
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A total of 575 drugs are known to interact with tizanidine:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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November 22, 1977 |
August 26, 1977 |
November 27, 1996 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.