Comparing Baclofen vs Flexeril
| Baclofen | Flexeril |
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| Baclofen | Flexeril cyclobenzaprine |
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Baclofen relieves muscle spasms associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Choose a suggestion below Muscle Spasm (Involuntary Hypertonicity)
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| More about Baclofen | More about Flexeril (cyclobenzaprine) | ||||||||
| Generic Status | |||||||||
| Availability | |||||||||
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Prescription only |
Prescription only |
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| Ratings & Reviews | |||||||||
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Baclofen has an average rating of 6.9 out of 10 from a total of 391 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
Flexeril has an average rating of 6.1 out of 10 from a total of 181 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 27% reported a negative effect. |
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| Drug Class | |||||||||
| Side Effects | |||||||||
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Commonly reported side effects include: drowsiness. See the full baclofen side effects document. |
See the full Flexeril side effects document. |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all baclofen prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Form(s) Available | |||||||||
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N/A | ||||||||
| Brand Names | |||||||||
| Fleqsuvy, Gablofen, Lioresal, Lioresal Intrathecal, Lyvispah, Ozobax | Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
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6.8 hours |
72 hours |
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| CSA Schedule** View glossary of terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | |||||||||
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A total of 356 drugs are known to interact with baclofen:
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A total of 393 drugs are known to interact with Flexeril:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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November 22, 1977 |
August 26, 1977 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.