Flexeril Interactions
There are 452 drugs known to interact with Flexeril (cyclobenzaprine), along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 92 are major, 354 are moderate, and 6 are minor.
- View all 452 medications that may interact with Flexeril
- View Flexeril alcohol/food interactions (1)
- View Flexeril disease interactions (2)
Most frequently checked interactions
View interaction reports for Flexeril (cyclobenzaprine) and the medicines listed below.
- albuterol
- albuterol
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- gabapentin
- gabapentin
- ibuprofen
- ibuprofen
- lisinopril
- lisinopril
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- metformin
- metformin
- Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- omeprazole
- prednisone
- prednisone
- tramadol
- tramadol
- trazodone
- trazodone
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Flexeril alcohol/food interactions
There is 1 alcohol/food interaction with Flexeril (cyclobenzaprine).
Flexeril disease interactions
There are 2 disease interactions with Flexeril (cyclobenzaprine) which include:
Report options
More about Flexeril (cyclobenzaprine)
- Flexeril consumer information
- Compare alternatives
- Reviews (238)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: skeletal muscle relaxants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Diazepam
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
