Flexeril Interactions
There are 451 drugs known to interact with Flexeril (cyclobenzaprine), along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 92 are major, 353 are moderate, and 6 are minor.
- View all 451 medications that may interact with Flexeril
- View Flexeril alcohol/food interactions (1)
- View Flexeril disease interactions (2)
Most frequently checked interactions
View interaction reports for Flexeril (cyclobenzaprine) and the medicines listed below.
- albuterol
- Ambien (zolpidem)
- aspirin
- Benadryl (diphenhydramine)
- clonazepam
- Cymbalta (duloxetine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- Neurontin (gabapentin)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Flexeril alcohol/food interactions
There is 1 alcohol/food interaction with Flexeril (cyclobenzaprine).
Flexeril disease interactions
There are 2 disease interactions with Flexeril (cyclobenzaprine) which include:
Report options
More about Flexeril (cyclobenzaprine)
- Flexeril consumer information
- Compare alternatives
- Reviews (237)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: skeletal muscle relaxants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Paracetamol
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Botox
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Tylenol
Tylenol is a pain reliever and a fever reducer used to treat many conditions such as headaches ...
Robaxin
Robaxin (methocarbamol) is used to treat skeletal muscle conditions such as pain or injury ...
Valium
Valium is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Learn ...
Advil
Advil (ibuprofen) reduces fever, pain and inflammation caused by headaches, toothaches, arthritis ...
Voltaren
Voltaren (diclofenac) is used to treat pain or inflammation caused by arthritis or ankylosing ...
Zanaflex
Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
