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User Reviews for Zanaflex

The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Condition Avg. Rating Reviews Compare
Muscle Spasm 7.8
89 reviews 50 medications
Cluster Headaches 7.6
6 reviews 36 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Zanaflex

Rin February 26, 2020

For Muscle Spasm: “I have been on this medication Zanaflex for a few months due to degenerative disc disease in my neck, spine and lower back...I also have arthritis in my neck and back with severe muscle spasms. This medicine has helped me so much. It's not addictive and not a controlled substance which is fantastic. I wont take pain pills....I take 4mg 3 times a day and it helps me sleep.”

10 / 10
Star · Taken for 10 years or more October 18, 2019

For Muscle Spasm: “I have been on this medication Zanaflex for 17 years, it has always helped, I've never developed a tolerance to it. It does put me to sleep but with my condition I need to rest. I have yet to find a drug that does what this drug does. I have tried flexerill, robaxin and baclofen none of them do what zanaflex does”

10 / 10
Cher July 8, 2019

For Muscle Spasm: “Tried Zanaflex today for the first works really good. Took the pain away. But it made me sleep for 10 I won't be taking it any more..”

8 / 10
Big E · Taken for less than 1 month June 12, 2019

“I have Spinal issus and several other issues - so many I can't remember what they are, but it is my back, and shattered tibia plate on left leg. I just got Zanaflex TODAY! I am already knowing this medicine is going to work.”

8 / 10
Hailan · Taken for less than 1 month May 3, 2019

For Muscle Spasm: “I just started on zanaflex and I've never experienced such an effective muscle relaxer. I have MS and get really painful spasms and cramps. Have been on Baclofen for years (which hasn't been particularly helpful) and have also tried flexeril and skelaxin, which also did nothing. After taking the zanaflex, I actually felt my muscles relaxing (imagine that!) and could feel blood moving/tingling through my system. Was wonderful. The only problem is that, as others have said, it makes you REALLY drowsy, so I can't take the recommended 4mg dose 3x a day. I'm taking a quarter tablet twice in the daytime and then a full tablet late in the evening when I'm winding down for bed. I will also note that I had been assuming that the occasional slurred speech I was experiencing was a sign of my worsening MS, and now I'm reading reviews showing that Baclofen sometimes does that (!). So, I'm eager to get off that for a bit and see if this might be a better option for me long-term.”

9 / 10
crazydude81 · Taken for less than 1 month October 19, 2018

For Muscle Spasm: “It works well to relieve pain, but at the cost of an astronomical exhaustion. This drug makes me so tired that walking to the fridge is a tremendous task. I could sleep on the floor. Probably the most effective muscle relaxer I've taken, but my quality of life - even 24 hours later - is nil.”

6 / 10
Lindsey · Taken for 1 to 2 years September 6, 2018

For Muscle Spasm: “It is very effective as a muscle relaxer for me”

10 / 10
CaDomino · Taken for 6 months to 1 year August 25, 2018

For Muscle Spasm: “I have severe muscle spasms in my neck. My doctor prescribed this when I was in her office in total agony. It was like heaven. I take 4mg tabs, but I can't do 3x a day, so I break one in half if needed, but I feel so good when I wake up. This drug has made a world of difference in my life.”

10 / 10
Tater · Taken for 1 to 2 years August 10, 2018

For Muscle Spasm: “I've been on this medication for about a year now I'm prescribed 4mg three times a day. I can't take the whole 4mg during the day or else I'll be to sedated so I break it in half. It has worked well for me especially when I can't sleep and I take a whole dose. I try not to take it everyday so I keep a low tolerance to it. I have fibromyalgia along with other health issues.”

6 / 10
Kelz · Taken for 1 to 6 months June 13, 2018

For Muscle Spasm: “For fibromyalgia muscle pain and knots. Taking 2mg at night, helps somewhat.”

6 / 10
Gina Hicks October 20, 2017

For Muscle Spasm: “Zanaflex has been wonderful for me!!”

10 / 10
Old Grandma · Taken for 6 months to 1 year October 15, 2017

For Muscle Spasm: “I am a retired nurse and was in a near fatal MVA several years ago putting an end to my career of nursing. I broke many bones and had to have some bones pieced together with screws and steel plates. My overall health is good but mobility issues were a problem as I had gained a lot of weight because of my activity level was severely decreased. I became severely depressed, couldn't sleep because the pain was so severe and only worsened as time went by. I couldn't use my hands at times because the spasms would be so bad that I at times was dropping items of whatever I was holding in my hands. My legs cramped so bad at night that it was almost impossible to get adequate sleep, My doctor started me then on Zanaflex. It has helped tremendously .”

Mama Dawn · Taken for 5 to 10 years October 8, 2017

For Muscle Spasm: “This medication helps me tremendously with muscle spasms.”

10 / 10
PastorCindy · Taken for 10 years or more July 27, 2017

For Muscle Spasm: “I have been taking Tizanadine for 10 yrs. for severe muscle spasticity in neck and back due to RSD/CRPS, plus spinal stenosis, bulging discs, and previous car accident neck and spine injuries. Dose: 4 mg, 3 daily, usually 4 mg in the morning and 8 mg at night. I have found it very helpful. At first, it was very sedating, but not after a year or so. It does help me sleep. Works best with the help of pain meds and Baclofen cream. I had a serious drug interaction with SSRI antidepressants (particularly Luvox): actually passed out in my soup at a restaurant the first time I took them together. Hope this helps.”

GgGi June 18, 2017

For Muscle Spasm: “Strained my rotator cuff, MD acute care practice prescribed 4mg. I asked both doctor and pharmacist if it was okay to take with Allegra D. Both said yes. Luckily I was safe at home. It was scary how sedated I was. I had set an alarm for an appointment 2hours after taking mess. I got out of bed and could hardly make it to the restroom. Needless to say I cancelled the appointment. Next time I took the Medicines separately and broke the 4 mg table into 1mg. I'm no lightweight but this was too strong for me.”

10 / 10
Anonymous4863 April 22, 2017

For Cluster Headaches: “I have suffered from daily migraines for over 20 years. Have tried many medicines through the years and this has really decreased the number I have. Went from daily to once every couple of weeks or so. I take 4 mg at bedtime every night and immitrex when I feel one coming on.”

9 / 10
OodlesOPoodles · Taken for 1 to 6 months March 25, 2017

For Cluster Headaches: “Absolutely love this medication. I suffer from chronic migraines and daily headaches. I take 4mg of Zanaflex at breakfast, 2mg at lunch, and 4mg at bedtime. I'll take 6mg during a migraine attack and it helps tremendously with the pain, helps me sleep, and actually helps with the nausea. Zanaflex made me very drowsy at first and still does taken at doses of 4mg. Overall, incredibly helpful drug!”

9 / 10
PharmasBitch · Taken for less than 1 month December 23, 2016

For Muscle Spasm: “Did not put me to sleep or help with pain. In fact it caused anxiety and made pain worse. I was on 4mg. at night for three days. Quit after that. Don't really know why I was put on it because did not have neck or back pain. I have intractable headache. I personally don't believe in off label uses for pharmaceuticals.”

1 / 10
Joshua Tree · Taken for 1 to 2 years October 5, 2016

For Muscle Spasm: “I just had L5-S1 Lumbar Herniated Disc Surgery.. 3 weeks after the surgery, I started leaning to the left due to fluid infection surrounding the disc.. My Dr gave me Oxycodone and Tizanidine for the excruciating pain.. Tizanidine / Zanaflex is definitely a 10 when it come to Sciatica and Spasms! Only lasts 3-4 hours, but it works best when combined with pain meds.. Hope y'all find this helpful..”

10 / 10
Samson80 September 17, 2016

For Muscle Spasm: “I have been on xanaflex 4mg 3x a day that I take at night ti help me sleep. It helps the muscle spasms in my legs and allows me to sleep. The only problem I have is that it only lasts 4 hours and then I wake up. Works best if you take thr xanaflex, wait 30 minutes and then eat something and the xanaflex will work that much better.”

6 / 10
booltr2 January 31, 2016

For Muscle Spasm: “Well, I really am satisfied w/this medicine. I take it combo w/my pain medication. I was in a car accident two years ago and aside from the pain meds helping me w/pain, this is what actually allows the muscles themselves able to relax so I can sleep better. The one I really can't stand is 'flexeril". I don't what the deal is w/that because of anything, it makes ALL of my extremeties "jump" restless leg, but restless EVERYWHERE...(the legs too). The big problem is actually I got a new pain dr., but he only believes in one muscle relaxer and that's baclofen, which does ansolutely NOTHING. His intern told me that I could take two at a time, and still nothing. ”

9 / 10
MonkeyTech January 5, 2016

For Muscle Spasm: “I have been taking zanaflex for about 2 years. The best thing about this medicine is it helps me sleep and for me there is no grogginess in the morning. I'm totally alert. Not like with other muscle relaxants. However the medicine usually last about 3-4 hours so it's quite common to wake up in the middle of the night. I give it an 8 because it does work really well for me however I wish the effects would last a little longer to get a full nights rest and also because I can't take it in the day because it knocks me out.....cold.”

8 / 10
egg plant · Taken for 5 to 10 years April 22, 2015

For Muscle Spasm: “I've been on these for about 8 years. They work good on low back pain, DJD and bulging disc on my neck. Along with other pain killers it works good, but don't drive while on them. They do make you sleepy fast and also they tend to lower your blood pressure and you will get dizzy standing up. You can get a good night sleep on them. I take one 4 mg 2 times a day.”

9 / 10
NicoleLynn615 · Taken for 1 to 6 months April 18, 2015

For Muscle Spasm: “I take this along with Baclofen to try and calm the tone and muscle spasms. Since adding the Xanaflex my muscle spasms don't last as long. However they do still occur quite frequently.”

3 / 10
loripnyl April 16, 2015

For Muscle Spasm: “So far so good.”

9 / 10