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Zanaflex User Reviews & Ratings (Page 4)

Zanaflex has an average rating of 7.6 out of 10 from a total of 116 reviews on Drugs.com. 67% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Zanaflex

Commonly mentioned side effects
  • Kt1...
  • Taken for less than 1 month
  • February 24, 2025

For Muscle Spasm "I was prescribed Zanaflex for muscle tightness in my neck due to DDD. I only took the medication a few times at night as directed. I can lay down and actually feel the medication start to relax my muscles, it also helps me get comfortable and get a good night's sleep. No crazy side effects."

9 / 10
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1 Report
  • LG7...
  • Taken for 6 months to 1 year
  • July 18, 2023

For Muscle Spasm "I took Zanaflex 4mg about a year ago, and it was giving me hallucinations and then knocking me out. I stopped taking it. My muscle spasms are getting worse and they had me on Flexeril, but it did nothing at all. So now I'm going to be starting on 2mg Zanaflex to see if a lower dose has fewer scary side effects."

8 / 10
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6 Report
  • Zor...
  • Taken for 2 to 5 years
  • July 14, 2021

For Muscle Spasm "I used Zanaflex for years, but with a pain pill, and the combo helped with back and neck pain. It does drop the blood pressure till you get used to it. So, never take more than one. Don't drive on them."

9 / 10
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6 Report

Frequently asked questions

  • Ell...
  • Taken for 2 to 5 years
  • April 2, 2022

For Muscle Spasm "I have thoracic kyphosis starting, on top of needing a hip replacement, so my spasms are unreal to the point where I cannot breathe. Zanaflex is absolutely astounding in helping me break the spasms. Zanaflex knocks me out, though, so I cannot work or drive when taking it."

10 / 10
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5 Report
  • Hur...
  • Taken for less than 1 month
  • January 10, 2022

For Muscle Spasm "It helped me sleep, but it made me dizzy and my thinking was off. It also made me nauseated. I was hurting so bad I actually took it four times in about 48 hours, even with the nausea. I was still feeling really off 36 hours after the last dose and would not have trusted my judgment at work. My brain not feeling right was much more concerning to me than the nausea. I have taken Flexeril in the past, but I have never felt like this."

2 / 10
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5 Report

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  • But...
  • Taken for less than 1 month
  • August 22, 2022

For Muscle Spasm "I developed some symptoms and found out I was in premenopause. One of those symptoms was terrible muscle tension. My doctor prescribed me tizanidine 4 mg twice a day for two weeks. It helped a lot, but it made me so sleepy. I couldn't take it any longer than two weeks because I also take psychiatric medication and it interferes. I got hormones from my ob/gyn to help with everything."

8 / 10
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4 Report
  • Pha...
  • Taken for less than 1 month
  • December 23, 2016

For Muscle Spasm "Did not put me to sleep or help with pain. In fact, it caused anxiety and made pain worse. I was on 4 mg at night for three days. Quit after that. Don't really know why I was put on it because I did not have neck or back pain. I have intractable headache. I personally don't believe in off-label uses for pharmaceuticals."

1 / 10
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36 Report
  • Pai...
  • Taken for less than 1 month
  • May 15, 2022

For Muscle Spasm "I've been on Zanaflex for about 2 weeks. I have a herniated disk. This helps a bit. I just wish that the side effect wasn't drowsy. I can only take it when I'm at home, which defeats the purpose, I need it during the day. Other than that, it's fine. Makes me sleep so well."

6 / 10
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3 Report
  • Ord...
  • Taken for 1 to 2 years
  • January 1, 2013

For Muscle Spasm "I found that this medicine managed the muscle spasms associated with the three herniated discs in the lumbar region of my back"

9 / 10
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113 Report
  • Che...
  • July 8, 2019

For Muscle Spasm "Tried Zanaflex today for the first time. It works really good. Took the pain away. But it made me sleep for 10 hours, so I won't be taking it anymore."

8 / 10
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52 Report
  • Anonymous
  • February 12, 2015

For Muscle Spasm "Prescribed after 4th lumbar fusion fail. Helps with sleeping in a painful condition"

6 / 10
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80 Report
  • dhb...
  • January 27, 2013

For Muscle Spasm "I have had very positive results with this medicine. I have MS and this helps reduce problems."

9 / 10
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82 Report
  • Lin...
  • Taken for 1 to 2 years
  • September 6, 2018

For Muscle Spasm "It is very effective as a muscle relaxer for me."

10 / 10
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46 Report
  • Hic...
  • Taken for less than 1 month
  • June 27, 2020

For Muscle Spasm "I took Zanaflex for not even a week. It worked so good, I thought I’d found the answer for my pain! But then it stopped working for me! Any ideas?"

10 / 10
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36 Report
  • Ga ...
  • Taken for 2 to 5 years
  • April 18, 2014

For Muscle Spasm "Zanaflex works great to relieve my lower back pain. However, it seems to keep me awake instead of helping me sleep. I rest well but just do not fall asleep."

9 / 10
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70 Report
  • Haz...
  • Taken for less than 1 month
  • April 23, 2021

For Muscle Spasm "Doesn’t help my lower back pain at all. Take 4 mg every 8 hours, cannot tell any difference."

1 / 10
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27 Report
  • ang...
  • April 2, 2008

For Muscle Spasm "This is the first one I found that works. I've been on a lot of muscle relaxers."

10 / 10
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93 Report
  • Kad...
  • May 15, 2008

For Muscle Spasm "I am now taking Zanaflex. I was on Soma for 6 years and this is the best I have felt in a long time. I have postoperative nerve damage and RSD and take a lot of pain medication."

7 / 10
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79 Report
  • Sup...
  • May 10, 2011

For Muscle Spasm "Make sure that you do not do anything where you need your balance. This medicine causes dizziness."

4 / 10
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63 Report
  • Mp3...
  • July 31, 2014

For Muscle Spasm "I take this for my spina bifida. Helps so much!"

10 / 10
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58 Report
  • cra...
  • February 18, 2013

For Muscle Spasm "This medicine helped for fibromyalgia but caused hallucinations and fatigue."

8 / 10
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75 Report
  • Mam...
  • Taken for 5 to 10 years
  • October 8, 2017

For Muscle Spasm "This medication helps me tremendously with muscle spasms."

10 / 10
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38 Report
  • Anonymous
  • May 13, 2008

For Muscle Spasm "Switched from Soma after 4 years, love this new drug, no feeling loopy, can manage my day and feel great."

9 / 10
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65 Report
  • Nic...
  • Taken for 1 to 6 months
  • April 18, 2015

For Muscle Spasm "I take this along with Baclofen to try and calm the tone and muscle spasms. Since adding the Zanaflex, my muscle spasms don't last as long. However, they do still occur quite frequently."

3 / 10
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53 Report
  • Itc...
  • March 9, 2011

For Muscle Spasm "Great medicine. I have herniated discs and take it with Percocet, and am able to relax."

9 / 10
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55 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.