Medications for Chronic Spasticity
What is Chronic Spasticity: Spasticity is stiff or rigid muscles with exaggerated, deep tendon reflexes (for example, a knee-jerk reflex). The condition can interfere with walking, movement, or speech.
Medications to treat Chronic Spasticity
The following list of medications are in some way related to, or used in the treatment of this condition.
| Drug name | Rx / OTC | Pregnancy | CSA | Alcohol | Reviews | Rating | Popularity |
|---|---|---|---|---|---|---|---|
| baclofen | Rx | C | N | X | 14 reviews | ||
|
Generic name: baclofen systemic Brand names: Lioresal, Gablofen, Lioresal Intrathecal, Kemstro … Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information |
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| Lioresal | Rx | C | N | X | 1 review | ||
|
Generic name: baclofen systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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| Dantrium | Rx | C | N | X | 1 review | Add | |
|
Generic name: dantrolene systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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| Gablofen | Rx | C | N | X | 2 reviews | ||
|
Generic name: baclofen systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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| Botox | Rx | C | N | 2 reviews | |||
|
Generic name: onabotulinumtoxinA systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information |
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| dantrolene | Rx | C | N | X | 2 reviews | ||
|
Generic name: dantrolene systemic Brand names: Dantrium, Revonto, Dantrium Intravenous Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information |
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| Lioresal Intrathecal | Rx | C | N | X | 2 reviews | ||
|
Generic name: baclofen systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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| Kemstro | Rx | C | N | X | Add review | Add | |
|
Generic name: baclofen systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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| Revonto | Rx | C | N | X | Add review | Add | |
|
Generic name: dantrolene systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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| Dantrium Intravenous | Rx | C | N | X | Add review | Add | |
|
Generic name: dantrolene systemic Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: Prescribing Information |
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| onabotulinumtoxinA | Rx | C | N | 2 reviews | |||
|
Generic name: onabotulinumtoxinA systemic Brand name: Botox Drug class: skeletal muscle relaxants For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, AHFS DI Monograph |
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Legend
| Off Label | This medication may not be approved by the FDA for the treatment of this condition. |
| Prescription Only / Over the Counter | |
|---|---|
| Rx | Prescription Only |
| OTC | Over the Counter |
| Rx/OTC | Prescription or Over the Counter |
| Pregnancy | |
|---|---|
| A | Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). |
| B | Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. |
| C | Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
| D | There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks. |
| X | Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits. |
| N | FDA has not classified the drug. |
| Controlled Substances Act Schedule | |
|---|---|
| N | Is not subject to the Controlled Substances Act. |
| 1 | Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
| 2 | Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
| 3 | Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
| 4 | Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
| 5 | Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
| Alcohol | |
|---|---|
| X | Interacts with Alcohol. |
