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User Reviews for Cymbalta to treat Chronic Pain (Page 3)

Cymbalta has an average rating of 5.9 out of 10 from a total of 141 ratings for the treatment of Chronic Pain. 52% of those users who reviewed Cymbalta reported a positive effect, while 33% reported a negative effect.

Cymbalta Rating Summary

5.9/10 average rating

141 ratings from 147 user reviews.

Compare all 50 medications used in the treatment of Chronic Pain.


Reviews for Cymbalta

AGnn · Taken for 2 to 5 years May 6, 2015

“While this med is fairly effective in the treatment of chronic pain, unless you plan to stay on it for the rest of your life you should not even consider taking it. Discontinuation of this medication has to be done under the supervision of a physician and the withdrawal is horrific, leaving one unable to function in a normal capacity for weeks, or even months. Most doctors don't mention this. Some aren't even aware of it. I urge you to be cautious in your decision to take Cymbalta. Google "Cymbalta withdrawal" first!”

5 / 10
PainOnMyNerves · Taken for 1 to 2 years January 24, 2018

“I was prescribed Cymbalta 90mg for nerve pain. Previously, I tried gabapentin, & Lyrica with significant side effects. However, with the Cymbalta, I noticed a huge difference within 24 hours after I started taking it. I did recently miss a couple days, and there is a noticeable withdrawal, mostly headaches. After missing the couple days, it has taken longer this time to kick back in. This tiny little pill has actually allowed me to lower my pain meds significantly and is treating my depression. I was able to stop both Prozac and Fentanyl (75mcg/48hrs). I do think, because of the possible withdrawal symptoms that one should first try gabapentin or Lyrica. For me, Cymbalta was a life changer; my miracle medicine!”

10 / 10
Pyj May 27, 2018

“I was taking amitriptyline for chronic pelvic pain for 6 years and was frustrated with the morning fatigue and weight gain. It did well to control the pain but was becoming less effective. The gynae changed me to duloxetine to hopefully spark some energy. The first two month later were awful. My pain returned and I felt like I had a sleeping sickness. I was irritable and nauseated all the time. Pain was decreasing slowly but I had to rely on strong pain killers. Two months in, I woke up one morning with no pain, feeling good. This feeling came more frequently over the next month until it was daily. The changes compared to amitriptyline are that I’m losing a bit of weight and the pain management is better. My memory is also improved. It seems to be helping more with the depression from the loss of my partner to cancer. I feel generally happier. Sleep problems are worse.”

8 / 10

Frequently asked questions

FibroC April 22, 2019

“I was prescribed Cymbalta for fibromyalgia and depression. I was taking it for over 3 years but I developed a tolerance for it because it stopped working. While I was on it, it worked really well. It took some time to take effect, like 15 days, but when it did it worked very well. I was able to continue working 50 hour weeks. The only horrible thing was when it finally stopped working so I had to resign from my job and subsequently lost my health insurance. I couldn't afford the Rx so I stopped taking it cold turkey. The side effects were horrendous! I was shaking, nauseous, had really bad headaches, dizzy. I finally had to borrow money to get the med back and then weaned off slowly.”

6 / 10
CissiePa · Taken for 1 to 6 months February 19, 2018

“I have had fibromyalgia for 30. yrs. My M.D was supportive, - resorted to hydrocodone. It worked, but I hated taking opiates. Then my husband died. My doctor upped my hydrocodone to 4, 10mg a day. My Fibro was worse. Went to a pain clinic. Awful. I went to a psychiatrist. He put me on a low dose of xanax, for crying nightly. Still Pain! I returned to the psychiatrist. I was on Cymbalta, 60 mg., for depression, but still had Fibro without opiates. Psychiatrist told me to take 60 more mg of Cymbalta. Next day I was a new person! No pain, wonderful mood.Everyone is different. I am off opiates, and down to 0.5 xanax.”

10 / 10
Marsey · Taken for less than 1 month March 9, 2018

“I'v been on Palexia SR 100mg and Pristiq 50mg for more than 2yrs for Chronic pain. Kept me functional, able to work etc. Told Dr I wanted to go off Pristiq, weaned off over 3 wks no problems. After 2 months my pain increased to unbearable even still taking Palexia. Revisited Dr about pain, Dr suggested Cymbalta 30mg. I read all the horror reviews, but needed to try something. Right from 2nd day, my pain s reduced by 60+%. No side effects. I can move like I have not moved in months. Amazing.”

10 / 10
JeanT October 12, 2014

“Cymbalta has helped enough for me to justify taking it for both chronic pain and dysthymia but do not stop it suddenly! I ran into a doctor vs Insurance problem and went cold turkey for a week and thought I would die. Wean very slowly. If you stop this medicine or stop down to a SSRI then eliminate that. It was the most horrible thing I had ever experienced. It has helped me though.”

7 / 10

More FAQ

DoctorA49 · Taken for less than 1 month August 29, 2019

“I have chronic pain from degenerative arthritis LS spine. Also have had 2 surgeries for spinal stenosis and foraminal stenosis. I tried Cymbalta about year ago and it did diminish the pain but side effects forced me to stop. I had severe insomnia and after two weeks of only sleeping 2 hours a night was coming apart. Also very difficult voiding my bladder and caused impotence at the same time. Tapered off and had auditory hallucinations like light saber sounds. If I could have tolerated the side effects would have continued since it did help the pain.”

8 / 10
Merytle May 22, 2014

“Cymbalta has given me such great relief from pain for many years. Unfortunately I fall in the 1% of severe side effects. I've had no need for narcotics except for acute pain for migraines or injuries during this time. Unfortunately I have put on so much weight and my liver is enlarged and enzymes are high due to taking this medicine. Even with years of intense exercising 3-5 days a week I was unable to lose any significant weight. I must now stop taking it and I don't know of anything else that will give me this relief. Still highly recommend this for others who are most likely not going to have this trouble. But be aware just in case you fall in the 1% also. Especially if taking other medicines.”

8 / 10
deba114620 June 18, 2016

“i was skeptical. Other meds had not worked for pain. The pain from spinal stenosis and other arthritis and nerve pain was decreased the day after I started taking it. The effectiveness diminished after a month so the dose was increased and it is working well . I have decreased other pain meds, can walk better and am able to do much more”

9 / 10
LJnDC · Taken for 1 to 6 months January 12, 2017

“I was prescribed Cymbalta 20mg @1/day, first thing in the morning for severe sciatic pain. After about 3 days I experienced considerable relief in my pain and stays away until around 8-8:30 PM. What I don't like is the constant sweating. I can be sitting still and start to sweat. It's all facial sweating and it can last for hours. I spoke with my doctor about it and she prescribed Wellbutrin to be taken with the Cymbalta. I tried it for a few days and that gave me diarrhea so I opted to deal with the sweats. Other side effect is muscle or involuntary jerking. Especially when I'm lying still in bed. I just wish big pharma could invent a pill that doesn't have so many side effects and just do what it's designed to do.”

8 / 10
austmanice · Taken for less than 1 month August 14, 2017

“I have had three back surgeries the latest was back fusion I now suffer from nerve pain especially in my right thigh and knee At times I can hardly walk due to the pain and weakness in my leg Xrays and MRI show the fusion is in the correct position but the Specialist have said I may always have this nerve pain They prescribed Cymbalta and oh what a calamity I only took this medication for 3 days and that was 3 too many I was not warned about possible side effects these are numerous Massive increase in pain Massive increase in weakness in the leg (had to use a walker) Chest pain Headaches Nausea Stomach pain Mood swings like anger suicidal thoughts Nightmares Hot and cold flushes Sweating for no reason list goes on”

2 / 10
6 weeks - Cymbalta · Taken for 1 to 6 months January 2, 2017

“It works in subtle ways. It was supposed to help with RA pain but it has actually helped my outlook on my daily life as well. I feel hope and have extra energy. This relief of pain has helped me be able to draw better boundaries around situations I was allowing to happen in my life. The side effects are mild. I also like that I am not gaining weight. Subtle changes, but works great and in ways I did not expect. It has not taken away my RA pain, but has muted it a bit.”

8 / 10
Kimmy1975 March 17, 2016

“I thankfully have never had depression! However I have chronic severe pain(ankylosing spondylitis) I tried cymbalta in my mid 30's... YES it made me EXTREMELY nauseous and I got headaches... But only for the first week! I felt like it gave me my life back.. But it was short lived and only took it for 6months because I ended up getting immuned to it. at 60mg /day It did nothing for pain! I went back on it at 39 after many failed attempts of other meds! But this time I also take dalaulid with it for break through pain (usually only need once but sometimes twice a day!!) I've been back on cymbalta for almost 2years now and feel like I have my life back! I'm able to work(I'm a waitress) and drive and LIVE life!”

9 / 10
Grandma Pat · Taken for 1 to 6 months September 30, 2019

“I was prescribed Cymbalta at 20 mg for pain following hip replacement. It didn’t help with pain, but I was sleeping so well that I kept taking it. Then the nightmares started and kept getting worse. I finally stopped taking the drug on my own after 4 months. The nightmares have stopped. But, surprisingly, my blood sugar which has been steadily climbing toward 200 is now back near 100. No change to anything else. I can only attribute this to the discontinuation of Cymbalta. And I feel much better.”

5 / 10
Twister2001 September 14, 2015

“My doctor put me on Cymbalta for chronic pain with Fribro/Arthritis/Bursitis/Bulging discs. I have been taking it for a week now and cant seem to shake some of the side effects. My pain is almost completely gone and I am so thankful for that. However, my eyes are so dilated all the time that everything is blurry and I practically live in a cave. In the 6 days I have been taking it I have lost almost 10 lbs, I am not sleeping (though they say this will get better) and during the day I am having so tired it takes everything in me to stay awake at work. My reflexes are lacking as well: I am dropping things, losing my balance and my reaction time when driving is a little sketchy. But all that aside, my pain is gone :)”

7 / 10
Anonymous · Taken for 2 to 5 years December 23, 2014

“I had blissfully forgotten how much pain I had been living with before taking Cymbalta, until I ran out unexpectedly. Pretty short half-life. The pain was debilitating and constant; much worse were the very unpleasant withdrawal symptoms which took hold very quickly - won't list them as they probably were related to my brain trauma. Obviously it's best not to run out, but if so, be aware of the withdrawal symptoms and pain returning. The good news is that all that unpleasantness is gone relatively quickly: 2-3 days. Another point: not covered by my insurance, and I take 90mg/day ($$$), but my G.P. spoke to Lilley (manufacturer) who agreed to provide me with 6 months worth at a time - gratis! Worth checking into.”

10 / 10
Alley 267 · Taken for 1 to 6 months March 4, 2017

“I was in an accident 3 months ago. I had extreme pain and finally I found a doctor who listened to me. After my accident and my lower buttocks legs and heels I could hardly move not including all the neck problems I had the first wee.k I felt some flu symptoms however one day I woke up and I have to say it made me 75% better I just got increased from 30 to 60 it seems like I might have some of the side effects. I first had my body a little flu like feeling, in my mind a little foggy, however if you're really taking this for nerve pain I would suggest this to anyone it has helped me more than anything. Starting next month I'm going to wean off of the narcotic pain pill I've taken 3 months all the bad reviews on most scared me from me but I tried”

10 / 10
John January 13, 2021

“I have Primary Progressive Multiple Sclerosis. I was prescribed Cymbalta for nerve pain. I was told it could cause diarrhea! I started on 30 mg per day, then after 2 weeks increased to 60mg per day. I have never experienced side effects from a medication as dangerous and scary then the ones I had while on Cymbalta. After a week of taking 60mg, I began having terrible stomach pain. A couple days later, my feet started to feel ice cold, but they were warm to the touch. I then began having trouble urinating, double vision, ringing in my ears, dizziness & severe headaches. I literally thought I was dying and close to death. My wife had looked up the possible side effects of Cymbalta I immediately called the prescribing doctor and he informed me to STOP CYMBALTA IMMEDIATELY!! I was instructed NOT TO STOP COLD TURKEY or else I could risk having life long damage from the side effects.”

1 / 10
Belva Watkins July 13, 2014

“The first pill very strong so waited till in bed and when the severe pain from shingles hit I took 2nd pill..instant relief. I was so glad I had the medicine and still have the bottle of pills as I never needed another. One pill got me through the worst pain I had with shingles. I would not have a need for any now but saved in case shingles returned. I think it a tad bit too strong for most pain that could be treated with a lessor degree of strength. 2 pills used out of whole bottle. It was expensive but actually just one pill did the job.”

10 / 10
rustyspur · Taken for 1 to 6 months October 28, 2013

“My rheumatologist had me on a very high dosage, so much that I had to pay for two seperate scripts at the pharmacy. I guess so many people do have a positive response to this med, my doctor thought increasing the med mg would result in symptom improvement, however that wasn't the case. I hated (that's a strong word for me) Cymbalta. I was told I acted like another person while on it and not in a good way. Even though I strictly followed my pharmacist and doctors directions when tapering off if this med, I still had severe withdrawal during and after reducing the mg. I even called the doctor and pharmacy because I was so concerned; I all but went to the emergency room in the beginning stages since I had never had withdrawal symptoms before.”

1 / 10
Ogr January 9, 2021

“Horrific, didn’t fix of my Post Vasectomy pain, and while on it didn’t care about anything, like making sure the kids were fed or care about stopping for red lights or getting to work on time. But the Doctor liked me being on it because I was tired all the time and slept lots, was more docile and didn’t complain about the pain. Just try it and watch your life go down the toilet. Would be good if I was in nursing home at the end of my life but I still have a life to live (only 50 years old).”

1 / 10
Felicia · Taken for 1 to 6 months February 24, 2021

“Medical Issues: chronic, back, muscle, joint, anxiety, PTSD and mild depression. I was on tramadol for 12 years. I was assaulted and strangled May 2020, which left me with the feeling of losing myself. Doc put me on klonopin which semi worked, I went back and told him I didn't feel "complete" He put me on Cymbalta. Getting off of it sucked. The first week I had problems sleeping. Also felt a sense of euphoria at first, relaxed like nothing in the world would bother me. I still have loss of appetite since starting Cymbalta, and weight loss. I don't get nearly as much deep sleep as I used to. I wake up randomly at 3 or 4 in the morning. 4 weeks in, this has helped my mood so much, I'm on a level playing field now as far as anxiety goes. So far, it's been a God send for my mental health and physically I wish for less pain, but it's better. I've noticed a difference with standing longer and less tossing and turning.”

8 / 10
Tough_it_up February 18, 2014

“I've been on Cmybalta for about one month. 1st week on 30mg and 2nd week on 60mg. Only side effect for the first 2 weeks was lucid dreams and insomnia. I have really bad nerve problem in the upper and lower back which causes a lot of stress to my shoulder trapezius and chest muscle. Cymbalta helps me manage the upper back, shoulder, trapezius and chest pain well enough, but nothing for the lower back. I noticed the pain reduction in the 2nd week. It's not a miracle pill but it sure helps.”

8 / 10
Losinghope007 November 10, 2015

“I have had fibro, Depression, anxiety, chronic horrible pain. Cymbalta does nothing at all. I don't even know why I take it. If you stop it's worse than stopping anything else I have ever tried to except maybe Xanax. I am so happy for all you that it works for. Life is depressing and miserable. Pain meds were the only thing that has helped for pain but I have been on them so long I want to try something else. So sick of people who think pain meds cause the problem. Of course I am on a higher dose than someone who just started. It's been ten years. I wish cymbalta helped as much as you guys.”

1 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.