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User Reviews for Cymbalta to treat Chronic Pain (Page 5)

Cymbalta has an average rating of 5.9 out of 10 from a total of 141 ratings for the treatment of Chronic Pain. 52% of those users who reviewed Cymbalta reported a positive effect, while 33% reported a negative effect.

Cymbalta Rating Summary

5.9/10 average rating

141 ratings from 147 user reviews.

Compare all 50 medications used in the treatment of Chronic Pain.


Reviews for Cymbalta

HHgirl August 6, 2015

“I have been taking Cymbalta for joint & muscle pain due to hemochromatosis for about 6 weeks now and it has made a huge difference, and I find that I have almost no side effects. For the first week or so the side effects were terrible, but they eased up after that.”

9 / 10
Marcia64 · Taken for 1 to 6 months May 5, 2013

“I was prescribed Cymbalta for a combination of chronic pain from osteoarthritis and major depressive disorder with melancholia. I started with 30mg for the first two weeks, but had to stop taking my daily 1200 to 1800mg of ibuprofen and also quit drinking. For depression, it was amazing. I felt relief from my despondency within a handful of days, and that has continued through this, my third month. I had my dose increased to 60mg to try and get relief from the chronic pain, but it has not been effective for me in addressing that - thus my rating. For depression, I give it a 10, but for pain (my experience) I have to give it at best, a 3. After consulting with my doctor, he said I could resume taking ibuprofen at a much lower dose.”

7 / 10
addy1234 May 24, 2015

“Instead of helping my headaches, cymbalta made them worse. With each dose increase, the severity of the pain increased, and so did my weight. In the year that I was on cymbalta, I gained sixty pounds. When I passed my pregnancy weight at nine months, I had finally had enough and took myself off. Never again!”

1 / 10

Frequently asked questions

MtRose July 16, 2015

“First placed on medication for severe arthritis of one hip. Helped with pain at the lower dose however eventually I needed an increased dose. The increased dose increased my nausea, weird dreams, itchy skin and twitching. My blood pressure also increased. I began to stumble and fall while walking slowly. My nerves seemed to cause me to tremble internally. Currently I am tired all the time however I can not stay asleep at night. Last year I tried to get off the medication however I had severe withdrawal. I had trouble standing up, I was so dizzy and my stomach was upset. I will soon be getting a hip replacement since the side effects decrease your quality of life. I am withdrawing from this medication prior to surgery.”

8 / 10
Adria August 18, 2018

“I was prescribed cymbalta yesterday and after taking only one pill I became incoherent. Thank goodness I was safe at home. I begin accusing my husband of things and spoke of things that made no sense. It was awful. I suffered some type of psychosis. I didn't recognize my husband and so forth. I even tried to call cops because I was scared of my family. It wore off after several hours . Very bad experience”

1 / 10
abnermalchik · Taken for 1 to 6 months August 11, 2015

“Was given 30mg cymbalta for pain in hip as well as depression due to chronic pain. It's been 2months, after about 3weeks of many side affects, diarrhea, nausea, headache, the pharmacy told me to stick with it, they will pass. They have except I've gained about 5lbs. The depression is better, the pain isn't any better, in fact seems to be getting worse. I don't think the cymbalta is making the pain worse, I think my hip is just getting worse. But not happy about the weight gain since I was fighting my weight before I took it. And being heavier can't be good for a bad hip.”

1 / 10
JuicyK81 July 11, 2017

“I have not actually taken this yet. My prescription will be ready by tomorrow. I'm scared, depressed, hopeful and in pain.... I hope I have good stories to share like the positive comments on here. I worry I'm going to be like the others.”

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Jenn Claus · Taken for 1 to 6 months January 30, 2015

“I was placed on Cymbalta for chronic pain as a result from injuries sustained in a head on car accident right before my 19th birthday that also caused 2 very rare recessive gene's to activate (hemiplegic migraines (neurological migraines) and Raynauds disease (circulation disorder) in my lower leg's and feet). At first the pain control was unbelievable. However, 2-3 months into my treatment I began having psychological repercussions where I felt like all my emotions were trapped inside my head. Although I felt angry, sad, happy, etc, I was unable to exhibit those emotions. Cymbalta was discontinued. My head injury was suspected to be the issue as to why I had the adverse reactions I did because my brain didn't function or process normally.”

1 / 10
Gintech · Taken for 6 months to 1 year March 14, 2013

“I can't take NSAIDS anymore, so tried Cymbalta. Worked great for my pain and my depression. HOWEVER, I had to stop it because of horrible side effects. The worst headaches I have ever had, dizziness, and eventually mood changes. I took it for about 7 months total, the last 2 months was tapering off. My Doctor had a patient end up hospitalized when they rushed the taper. ”

8 / 10
Chollymike · Taken for 5 to 10 years January 2, 2013

“I have chronic nerve pain and RSD as a result of a failed multi-level cervical fusion. I was on narcotics for 2 - 3 years. I had an implanted pulse generator placed in my low back with the leads running up my spine to the area in my neck affected by the surgery. This enabled me to get off the narcotics, but I still have trouble with the Reflex Sympathetic Dystrophy (RSD). About 5 years ago, my doctor put me on Cymbalta. I now take 60mg each morning.There has been a marked difference in my pain level as a result. I have learned to regulate my activity as well to help keep the pain down. I still have moderate bouts of depression. So far, nothing has a lasting effect on that.”

5 / 10
MsBunky · Taken for 2 to 5 years October 10, 2012

“I have been using Cymbalta for several years now as part of my treatment plan for Chronic Pain. My pain is related to having Fibromyalgia, osteoarthritis in my hips, spine, knees and neck, impingement in the hips as well, and trigger points throughout my body. After trying several other medications, and gaining some amount of weight, my doctor wrote the prescription and I started at 30mg for the day. I now take 60mg in the morning and 60mg at night and it makes a huge difference in maintaining my pain levels. I use it now as part of my daily "medicine cocktail" and hope to continue for a long time still to come!”

8 / 10
Meg444 January 8, 2021

“Horrible Experience! Two hours after I took Cymbalta, out of no where my heart started beating so fast I thought I was having a heart attack. I couldn’t breathe. My chest and arms started burning. Heat washed over me. I had no clue what was going on. Then I remembered the Cymbalta. I panicked and ran to the bathroom to try and throw it up. It was too late. I thought it was so bad for me. I had never had a panic attack in my life. Not once. I laid on the bed and tried to control my breathing. 6 hours of panic attacks and a trip to the ER finally stopped them. Since then, I have had many more panic attacks. After one pill of Cymbalta, things that never bothered me before.. like Epinephrin in the dentist chair are suddenly causing panic attacks. This morning I woke up to a panic attack yet its been 9 months since I took it! It would seem, that Cymbalta gave me a panic disorder. I wish I had never taken it.”

1 / 10
Philly Dog August 31, 2015

“Was taking this along with 450mg of Lyrica a day and 150mg of Tramadol a day. Nothing helped with pain but I went into such a depression that I could no longer even go out into public. I slowly weened myself off of all of it. I have pain but at least I can go out into the public.”

2 / 10
Karen H · Taken for less than 1 month December 10, 2015

“I just started on Cymbalta for excruciating nerve pain behind my right ear. This nerve pain is due to nerve damage from Shingles, PHN. I have to say that I am quite happy with the results so far. It seemed to zap the pain in about an hour from taking my first one. It seems to wear off by the next morning so I am going to try to up it to twice a day, hopefully I will not have trouble sleeping.”

7 / 10
mishiegov April 29, 2018

“I was on Cymbalta for nearly 4 years. I was on the 60mg and just after I turned 40 I began the drug not realizing I was heading for the most horrific experience of my life. After stopping it I had it all... the vomiting, nausea, headaches (migraines ), insomnia, brain zaps, nightmares , fever, loss of appetite... flu . It all came gushing at once. It was 9 days of hell so far but each day it’s getting better. I have never craved to go back on it and threw it all down the sink. No doctor helped me go off it. I made the choice. It was the best decision. I had attributed my night sweats and hot flushes and weight gain to me turning 40 even though the doctors had done the tests and it said I was not premenopausal. To think I decided to stop it because I couldn’t deal with the weight gain even though I had tried , Yoga, meditation, exercise, eating healthy. I gained about 18 pounds. Please think twice before going on this drug. The coming off doesn’t outweigh the lesser pain.”

4 / 10
Anonymous · Taken for 2 to 5 years May 19, 2014

“I have been taking Cymbalta for about 2 years. I can tell a major difference with an over all improvement and/or tolerance level of pain; I can ,as well, tell that it seems to improve the efficacy of two other medications I am given (morphine and tramadol) Or prescribed, as compared to when I (have done one or two trial periods purposefully x1 and accidentally) missed 4-7 days of not taking the Cymbalta.”

7 / 10
AJC1970 · Taken for less than 1 month January 19, 2017

“I was given Cymbalta in October to help with chronic back pain from a spinal fusion surgery due to no one catching a 33 degree scoliosis curve which was also affecting my breathing. My mother passed in September, so my PAIN SPECIALIST decided I needed something for anxiety/depression AND pain..ya think? So he told me to take it for a few weeks and tell him if I like it, and if I think it helps. Well, no mood lifting, no pain relief. Luckily I had no side effects to speak of, so I am sorry for those of us that doctors just hand meds to without explaining anything. Yes, he just prescribed them, and said "They should help." NO warnings, then we get the effects and they look at us like we are crazy. He tried to give me Cymbalta a second time!”

1 / 10
Anonymous · Taken for 1 to 2 years October 18, 2015

“Have had pain all my life, some is from fibromyalgia. Cymbalta worked well for pain such as the electrical zapping sensations. However, it is much too expensive and was not very effective for anxiety or depression.”

7 / 10
Anonymous · Taken for less than 1 month September 19, 2012

“I have fibromyalgia - panic disorder, bi-polar & ADHD -- I did not find Cymbalta to be any relief at all (included in my daily medication) if anything I was throwing up and feeling worse!! For those of you that it worked I am glad you no longer suffer as much. For me I still have to find the right pain medicine.”

Artist · Taken for 1 to 6 months April 14, 2018

“My MD prescribed Cymbalta for me for arthritic pain and depression due to multiple sleep disorders. I need knee, arm and hand surgeries as well. Cymbalta is not helping. I started with 20mg. Horrific nausea. Waited 48 hours, re-started with 10 mg as I separated 20 mg capsules into two doses. Took the 10mg doses three more nights. The nausea has not gone away. Tonight after missing yesterday's 10mg dose, the nausea has lifted a tiny bit. Also I have had trouble with urination and that apparently is another side effect. I will not take this again. Today I researched this med. Seattle Times April 8, 2018 has run a story condemning pharmaceutical companies for doing no research regarding side effects and helping people stop anti-depressants. No thanks, I am focusing back on art, exercise, diet, and maintaining friendships.”

1 / 10
Nick · Taken for 1 to 6 months March 8, 2018

“Cymbalta was prescribed to me for neuropathy pain - it didn't work! Instead I was cursed with the following side effects: gained 28 pounds in 2 months, lethargy, gynocomasty (breasts for men), sky high cholesterol and a severely damaged metabolism, impotence and near sterility. I can ravage the male body. Avoid this drug at all costs - IT IS NOT A CURE ALL.”

1 / 10
Tnouche February 2, 2017

“I started taking cymbalta for chronic pain about a week ago.I give it a 9 that s how good it is for my chronic lower back pain no tramadol needed”

9 / 10
Poggy · Taken for 1 to 6 months November 23, 2019

“I feel this has helped my back pain but possible side effect are loose bowels loss of appetite and lost weight. Not sure if should continue”

6 / 10
scoz July 18, 2016

“I started taking Cymbalta one month ago and saw positive results almost immediately. I was injured in a rear end collision 18 years ago”

9 / 10
Beau58 · Taken for 1 to 6 months October 10, 2019

“I can't even tell I'm taking anything, and I am taking 60 mg doses”

1 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.