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Medications for Chronic Pain

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
oxycodone 5.9 654 reviews for oxycodone to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Brand names:
OxyContin, Roxicodone, Oxyfast, Xtampza ER, Dazidox, ETH-Oxydose, Oxaydo, Oxydose, RoxyBond
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
tramadol 5.9 270 reviews for tramadol to treat Chronic Pain Rx C 4 X
Generic name:
tramadol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dilaudid 8.3 76 reviews for Dilaudid to treat Chronic Pain Rx C 2 X
Generic name:
hydromorphone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cymbalta 5.8 200 reviews for Cymbalta to treat Chronic Pain Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
OxyContin 7.9 98 reviews for OxyContin to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetaminophen / oxycodone 5.4 426 reviews for acetaminophen / oxycodone to treat Chronic Pain Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Brand names:
Percocet, Primlev, Nalocet, Xolox, Prolate
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Roxicodone 8.8 40 reviews for Roxicodone to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Percocet 7.9 47 reviews for Percocet to treat Chronic Pain Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
duloxetine 5.8 239 reviews for duloxetine to treat Chronic Pain Rx C N X
Generic name:
duloxetine systemic
Brand names:
Cymbalta, Irenka
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
hydromorphone 7.9 142 reviews for hydromorphone to treat Chronic Pain Rx C 2 X
Generic name:
hydromorphone systemic
Brand name:
Dilaudid
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
buprenorphine 5.4 510 reviews for buprenorphine to treat Chronic Pain Rx C 3 X
Generic name:
buprenorphine systemic
Brand names:
Butrans, Belbuca, Buprenex
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
methadone 8.6 174 reviews for methadone to treat Chronic Pain Rx C 2 X
Generic name:
methadone systemic
Brand names:
Methadone Diskets, Methadose
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
morphine 7.0 191 reviews for morphine to treat Chronic Pain Rx C 2 X
Generic name:
morphine systemic
Brand names:
MS Contin, Kadian, Infumorph, Astramorph PF, Duramorph, Duramorph PF
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Butrans 6.0 154 reviews for Butrans to treat Chronic Pain Rx C 3 X
Generic name:
buprenorphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
MS Contin 7.7 52 reviews for MS Contin to treat Chronic Pain Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
fentanyl 7.6 190 reviews for fentanyl to treat Chronic Pain Rx C 2 X
Generic name:
fentanyl systemic
Brand names:
Duragesic, Fentora, Actiq, Lazanda, Subsys
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Duragesic 8.6 29 reviews for Duragesic to treat Chronic Pain Rx C 2 X
Generic name:
fentanyl systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
gabapentin Rate Add review Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Kadian 7.9 19 reviews for Kadian to treat Chronic Pain Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oxyfast 9.7 3 reviews for Oxyfast to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
acetaminophen 5.0 1 review for acetaminophen to treat Chronic Pain Rx/OTC C N X
Generic name:
acetaminophen systemic
Drug class:
miscellaneous analgesics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Belbuca 4.5 226 reviews for Belbuca to treat Chronic Pain Rx C 3 X
Generic name:
buprenorphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ibuprofen 6.0 3 reviews for ibuprofen to treat Chronic Pain Rx/OTC C N X
Generic name:
ibuprofen systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xtampza ER 3.9 145 reviews for Xtampza ER to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Buprenex 10 1 review for Buprenex to treat Chronic Pain Rx C 3 X
Generic name:
buprenorphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Irenka Rate Add review Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
amitriptyline 7.5 2 reviews for amitriptyline to treat Chronic Pain Rx C N X
Generic name:
amitriptyline systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
celecoxib Rate Add review Rx C N
Generic name:
celecoxib systemic
Drug class:
cox-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Fentora 9.3 3 reviews for Fentora to treat Chronic Pain Rx C 2 X
Generic name:
fentanyl systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocodone 7.7 3 reviews for hydrocodone to treat Chronic Pain Rx C 2 X
Generic name:
hydrocodone systemic
Drug class:
Opioids (narcotic analgesics), antitussives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Methadone Diskets 9.6 10 reviews for Methadone Diskets to treat Chronic Pain Rx C 2 X
Generic name:
methadone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
naloxone / pentazocine 8.3 11 reviews for naloxone / pentazocine to treat Chronic Pain Rx C 4 X
Generic name:
naloxone / pentazocine systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
pregabalin 8.5 2 reviews for pregabalin to treat Chronic Pain Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dazidox 3.2 10 reviews for Dazidox to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
diclofenac Rate Add review Rx D N X
Generic name:
diclofenac systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ETH-Oxydose Rate Add review Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
Infumorph 9.0 2 reviews for Infumorph to treat Chronic Pain Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Methadose 8.8 10 reviews for Methadose to treat Chronic Pain Rx C 2 X
Generic name:
methadone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
naproxen 8.7 3 reviews for naproxen to treat Chronic Pain Rx/OTC C N X
Generic name:
naproxen systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Primlev 9.0 2 reviews for Primlev to treat Chronic Pain Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ziconotide 4.5 13 reviews for ziconotide to treat Chronic Pain Rx C N X
Generic name:
ziconotide systemic
Brand name:
Prialt
Drug class:
miscellaneous analgesics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Actiq 8.0 1 review for Actiq to treat Chronic Pain Rx C 2 X
Generic name:
fentanyl systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Astramorph PF Rate Add review Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Duramorph 2.5 2 reviews for Duramorph to treat Chronic Pain Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lazanda Rate Add review Rx C 2 X
Generic name:
fentanyl systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Nalocet 6.5 2 reviews for Nalocet to treat Chronic Pain Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oxaydo 4.1 15 reviews for Oxaydo to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oxydose 8.0 1 review for Oxydose to treat Chronic Pain Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
Prialt 4.3 11 reviews for Prialt to treat Chronic Pain Rx C N X
Generic name:
ziconotide systemic
Drug class:
miscellaneous analgesics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
RoxyBond Rate Add review Rx N 2 X
Generic name:
oxycodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Subsys 8.2 6 reviews for Subsys to treat Chronic Pain Rx C 2 X
Generic name:
fentanyl systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xolox Rate Add review Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
codeine 10 1 review for codeine to treat Chronic Pain Rx C 2 X
Generic name:
codeine systemic
Drug class:
Opioids (narcotic analgesics), antitussives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Duramorph PF Rate Add review Rx C 2 X
Generic name:
morphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
nortriptyline Rate Add review Rx N N X
Generic name:
nortriptyline systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Prolate 7.5 2 reviews for Prolate to treat Chronic Pain Rx C 2 X
Generic name:
acetaminophen / oxycodone systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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