Diclofenac Interactions
There are 444 drugs known to interact with diclofenac, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 97 are major, 330 are moderate, and 17 are minor.
- View all 444 medications that may interact with diclofenac
- View diclofenac alcohol/food interactions (2)
- View diclofenac disease interactions (11)
Most frequently checked interactions
View interaction reports for diclofenac and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Ozempic (semaglutide)
- Paracetamol (acetaminophen)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Diclofenac alcohol/food interactions
There are 2 alcohol/food interactions with diclofenac.
Diclofenac disease interactions
There are 11 disease interactions with diclofenac which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- porphyria
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about diclofenac
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- Compare alternatives
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- Reviews (695)
- Drug images
- Latest FDA alerts (11)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Qulipta
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Taltz
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Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
