Medications for Aseptic Necrosis

Other names: Avascular Necrosis; AVN; Ischemic bone necrosis; Osteonecrosis

Aseptic necrosis is bone death caused by poor blood supply to the area. It is most common in the hip, knee, and shoulder.

Drugs used to treat Aseptic Necrosis

The following list of medications are in some way related to or used in the treatment of this condition.

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Brands and Generics

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Rx and OTC

Drug name	Rating	Reviews	Rx/OTC	Pregnancy	CSA	Alcohol
ibuprofen	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Brand names: Advil, Motrin, A-G Profen, Addaprin, Genpril, Nuprin, Proprinal, Midol IB, Motrin IB, IBU-200 …show all Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

alendronate Off-label	Rate	Add review	Rx	C	N
Generic name: alendronate systemic Brand names: Fosamax, Binosto Drug class: bisphosphonates For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

aspirin	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Brand names: Bayer Aspirin, Easprin, Arthritis Pain, Ecotrin, Entercote, Halfprin, Aspergum, Aspiritab, Ecpirin, Genacote, Norwich Aspirin, Vazalore, Aspirtab, Bayer Aspirin Extra Strength Plus …show all Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

diclofenac	0.0	1 review for diclofenac to treat Aseptic Necrosis	Rx	D	N	X
Generic name: diclofenac systemic Brand names: Voltaren, Cataflam Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

naproxen Off-label	Rate	Add review	Rx/OTC	C	N	X
Generic name: naproxen systemic Brand names: Aleve, Naprosyn, All Day Relief, Anaprox, Anaprox-DS, Flanax Pain Reliever, Aflaxen, All Day Pain Relief, EC-Naprosyn, Midol Extended Relief, Naprelan …show all Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

Voltaren	Rate	Add review	Rx	D	N	X
Generic name: diclofenac systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Fosamax Off-label	Rate	Add review	Rx	C	N
Generic name: alendronate systemic Drug class: bisphosphonates For consumers: dosage, interactions, side effects For professionals: Prescribing Information Off-label: Yes

Advil	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Bayer Aspirin	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Aleve Off-label	Rate	Add review	Rx/OTC	C	N	X
Generic name: naproxen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects Off-label: Yes

Cataflam	Rate	Add review	Rx	D	N	X
Generic name: diclofenac systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Easprin	Rate	Add review	Rx	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Arthritis Pain	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Motrin	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Ecotrin	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Entercote	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Halfprin	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

A-G Profen	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects

Addaprin	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects

Aspergum	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Aspiritab	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Ecpirin	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Genacote	Rate	Add review	Rx/OTC	N	N	X
Generic name: aspirin systemic Drug class: salicylates, platelet aggregation inhibitors For consumers: dosage, interactions, side effects

Genpril	Rate	Add review	Rx/OTC	C	N	X
Generic name: ibuprofen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects

Naprosyn Off-label	Rate	Add review	Rx/OTC	C	N	X
Generic name: naproxen systemic Drug class: Nonsteroidal anti-inflammatory drugs For consumers: dosage, interactions, side effects For professionals: Prescribing Information Off-label: Yes

Frequently asked questions

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Rating	For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity	Activity is based on recent site visitor activity relative to other medications in the list.
Rx	Prescription only.
OTC	Over-the-counter.
Rx/OTC	Prescription or Over-the-counter.
Off-label	This medication may not be approved by the FDA for the treatment of this condition.
EUA	An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access	Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.

Pregnancy Category
A	Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B	Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C	Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D	There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X	Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N	FDA has not classified the drug.

Controlled Substances Act (CSA) Schedule
M	The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U	CSA Schedule is unknown.
N	Is not subject to the Controlled Substances Act.
1	Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2	Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3	Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4	Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5	Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Alcohol
X	Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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